The -590CC genotype in the IL4 gene as a strong predictive factor for the development of hypothyroidism in Hashimoto disease

Clinical Chemistry

Volumn 54, Issue 3, 2008, Pages 621-623

  Nanba, Takashi ^a   Watanabe, Mikio ^a   Akamizu, Takashi ^b   Iwatani, Yoshinori ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4; LEVOTHYROXINE;

CYTOKINE PRODUCTION; DISEASE SEVERITY; DNA POLYMORPHISM; GENETIC ANALYSIS; GENOTYPE; HASHIMOTO DISEASE; HUMAN; HYPOTHYROIDISM; IMMUNOREGULATION; INFLAMMATION; LETTER; PREDICTION;

GENOTYPE; GRAVES DISEASE; HASHIMOTO DISEASE; HUMANS; HYPOTHYROIDISM; INTERLEUKIN-4; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS;

EID: 40449138705     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2007.099739     Document Type: Letter

References (5)

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5. Mitsuyasu H, Izuhara K, Mao XQ, Gao PS, Arinobu Y, Enomoto T, et al. Ile50Val variant of IL4Rα upregulates IgE synthesis and associates with atopic asthma. Nat Genet 1998;19:119-20.