Growth inhibition and G1 cell cycle arrest mediated by 25-methoxyhispidol A, a novel triterpenoid, isolated from the fruit of Poncirus trifoliata in human hepatocellular carcinoma cells

Planta Medica

Volumn 74, Issue 2, 2008, Pages 151-155

  Hong, Ji Young ^a   Min, Hye Young ^a   Guang, Hua Xu ^b   Lee, Jong Gu ^b   Lee, Seung Ho ^b   Young, Shik Kim ^c   Sam, Sik Kang ^c   Sang, Kook Lee ^a  

^a Ewha Womans University   (South Korea)

^b Yeungnam University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

25 methoxyhispidol A; Cell growth inhibition; Poncirus trifoliata (L.) Raf.; Rutaceae; SK HEP 1 cells

Indexed keywords

25 METHOXYHISPIDOL A; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; RETINOBLASTOMA PROTEIN; TRITERPENOID; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CARCINOMA CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; DRUG ISOLATION; FLOW CYTOMETRY; FRUIT; GROWTH INHIBITION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PROTEIN PHOSPHORYLATION; TRIFOLIATE ORANGE;

ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; FRUIT; HUMANS; LIVER NEOPLASMS; PLANT COMPONENTS; PLANT EXTRACTS; PONCIRUS; TRITERPENES;

PONCIRUS TRIFOLIATA; RUTACEAE;

EID: 40449137626     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1034286     Document Type: Article

References (15)