Vascular Endothelial Growth Factor (VEGF) receptor antibody bevacizumab (Avastin) induces regression of renal cell carcinoma in an adolescent resulting in residual tumorectomy

Pediatric Blood and Cancer

Volumn 50, Issue 4, 2008, Pages 903-904

  Joshi, Divya Devi ^a   Banerjee, Tarit ^a  

^a MARSHFIELD CLINIC   (United States)

Author keywords

Anti angiogenesis; Rare tumor; Renal tumor; Tumor regression

Indexed keywords

BEVACIZUMAB; INTERLEUKIN 2; IRON;

ADOLESCENT; AMENORRHEA; ARTICLE; CANCER IMMUNOTHERAPY; CANCER REGRESSION; CANCER SURGERY; CASE REPORT; DRUG MEGADOSE; DRUG WITHDRAWAL; FEMALE; HUMAN; INOPERABLE CANCER; KIDNEY CARCINOMA; LYMPHADENOPATHY; NEPHRECTOMY; PRIORITY JOURNAL; PROTEINURIA;

ADOLESCENT; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; CARCINOMA, RENAL CELL; FEMALE; HUMANS; INTERLEUKIN-2; KIDNEY NEOPLASMS; LYMPHATIC METASTASIS; NEOPLASM, RESIDUAL; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR;

EID: 40449126434     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.21243     Document Type: Article

References (11)

1. Indolfi P, Terenziani M, Casale F, et al. Renal cell carcinoma in children: A clinicopathologic study. J Clin Oncol 2003;21:530-535.
2. Motzer R, Bander N, Nanus D. Renal cell carcinoma. NEJM 1996;335.
3. Cook A, Lorenzo A, Salle J, et al. Pediatric renal cell carcinoma: Single institution 25-year case series and initial experience with partial nephrectomy. J Urol 2006;175:1456-1460.
4. Estrada C, Suthar A, Eaton S, et al. Renal cell carcinoma: Children's hospital of Boston experience. Urology 2006;66.
5. Tsai H, Chin T, Chang J, et al. Renal cell carcinoma in children and young adults. J Chin Med Assoc 2006;69 240-244.
6. Bukowski R. Cytokine combinations: Therapeutic use in patients with advanced renal cell carcinoma. Semin Oncol 2000;27:204-212.
7. Abubakr Y, Chou T, Redman B. Spontaneous remission of renal cell carcinoma: A case report and immunological correlates. J Urol 1994;152:156-157.
8. Lawrentschuk N, Davis I, Bolton D, Positron emission tomography, immuno-Pet and radioimmunotherapy in renal cell carcinoma: A developing diagnostic and therapeutic relationship. BJU Int 2006;97:916-922.
9. Yang J, Haworth L, Sherry R, et al. A randomized trial of Bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. NEJM 2003;349.
10. Canfield S, Kamat A, Sanchez-Ortiz R, et al. Renal cell carcinoma with nodal metastases in the absence of distant metastatic disease: The impact of aggressive surgical resection on patient outcome. J Urol 2006;175:864-869.
11. Coppin C, Porzsolt F, Awa A, et al. Immunotherapy for advanced renal cell cancer. Cochrane Database Syst Rev 2005;4.