Dicholine salt of succinic acid, a neuronal insulin sensitizer, ameliorates cognitive deficits in rodent models of normal aging, chronic cerebral hypoperfusion, and beta-amyloid peptide-(25-35)-induced amnesia

BMC Pharmacology

Volumn 8, Issue , 2008, Pages

  Storozheva, Zinaida I ^a   Proshin, Andrey T ^a   Sherstnev, Vladimir V ^a   Storozhevykh, Tatiana P ^b   Senilova, Yana E ^b   Persiyantseva, Nadezhda A ^b   Pinelis, Vsevolod G ^b   Semenova, Natalia A ^c   Zakharova, Elena I ^d   Pomytkin, Igor A ^e  

^a P K ANOKHIN INSTITUTE OF NORMAL PHYSIOLOGY   (Russian Federation)

^b Russian Academy of Medical Sciences   (Russian Federation)

^c SEMENOV INSTITUTE OF CHEMICAL PHYSICS   (Russian Federation)

^d INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

^e Biosignal Ltd   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE ACETYLTRANSFERASE; CREATINE; DICHOLINE SUCCINATE; INSULIN RECEPTOR; INSULIN SENSITIZING AGENT; N ACETYLASPARTIC ACID; SODIUM CHLORIDE; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); CHOLINE; DICOLIN; DRUG DERIVATIVE; INSULIN; PEPTIDE FRAGMENT; PIPECOLIC ACID DERIVATIVE; SUCCINIC ACID;

AGING; ALZHEIMER DISEASE; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENZYME ACTIVITY; LOCOMOTION; MALE; MAZE TEST; MOUSE; MULTIINFARCT DEMENTIA; NERVE CELL CULTURE; NONHUMAN; PASSIVE AVOIDANCE; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RAT; TREATMENT DURATION; ANIMAL; BRAIN CIRCULATION; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; METABOLISM; NERVE CELL; PHOSPHORYLATION; PSYCHOLOGICAL ASPECT;

AGING; AMNESIA; AMYLOID BETA-PROTEIN; ANIMALS; CEREBROVASCULAR CIRCULATION; CHOLINE; COGNITION DISORDERS; INSULIN; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; NEURONS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PIPECOLIC ACIDS; RECEPTOR, INSULIN; SUCCINIC ACID;

EID: 40449120590     PISSN: None     EISSN: 14712210     Source Type: Journal    
DOI: 10.1186/1471-2210-8-1     Document Type: Article

References (67)