Pretreatment frontal EEG and changes in suicidal ideation during SSRI treatment in major depressive disorder

Acta Psychiatrica Scandinavica

Volumn 117, Issue 4, 2008, Pages 271-276

  Iosifescu, D V ^a   Greenwald, S ^b   Devlin, P ^b   Perlis, R H ^a   Denninger, J W ^a   Alpert, J E ^a   Fava, M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Aspect Medical Systems Inc   (United States)

Author keywords

Major depressive disorder; Quantitative electroencephalography; Selective serotonin reuptake inhibitors; Suicidal ideation

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; ESCITALOPRAM; FLUOXETINE; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; VENLAFAXINE;

ADULT; ALPHA RHYTHM; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE EXACERBATION; DISEASE SEVERITY; ELECTROENCEPHALOGRAM; FEMALE; FRONTAL CORTEX; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; OPEN STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SUICIDAL IDEATION; THETA RHYTHM; TREATMENT DURATION;

ADOLESCENT; ADULT; BRAIN; DEPRESSIVE DISORDER, MAJOR; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; FEMALE; FRONTAL LOBE; FUNCTIONAL LATERALITY; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; ROC CURVE; SEROTONIN UPTAKE INHIBITORS; SEVERITY OF ILLNESS INDEX; SUICIDE, ATTEMPTED;

EID: 40449095126     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/j.1600-0447.2008.01156.x     Document Type: Article

References (31)

1. Healy D, Whitaker C. Antidepressants and suicide: risk-benefit conundrums J Psychiatry Neurosci 2003 28 : 331 337.
2. Khan A, Warner HA, Brown WA. Symptom reduction and suicide risk in patients treated with placebo in antidepressant clinical trials: an analysis of the Food and Drug Administration database. Arch Gen Psychiatry 2000 57 : 311 317.
3. Laughren TP. The scientific and ethical basis for placebo-controlled trials in depression and schizophrenia: an FDA perspective. Eur Psychiatry 2001 16 : 418 423.
4. Storosum JG, van Zwieten BJ, van den Brink W, Gersons BP, Broekmans AW. Suicide risk in placebo-controlled studies of major depression. Am J Psychiatry 2001 158 : 1271 1275.
5. FDA proposes new warnings about suicidal thinking, behavior in young adults who take antidepressant medications, May 2, 2007, http://www.fda.gov/bbs/ topics/NEWS/2007/NEW01624.html (accessed on 28 January 2008).
6. Søndergård L, Kvist K, Lopez AG, Andersen PK, Kessing LV. Temporal changes in suicide rates for persons treated and not treated with antidepressants in Denmark during 1995-1999. Acta Psychiatr Scand 2006 114 : 168 176.
7. Teicher MH, Glod CA, Cole JO. Antidepressant drugs and the emergence of suicidal tendencies. Drug Saf 1993 8 : 186 212.
8. Busch KA, Fawcett J, Jacobs DG. Clinical correlates of inpatient suicide. J Clin Psychiatry 2003 64 : 14 19.
9. Perlis RH, Beasley CM Jr., Wines JD Jr. et al. Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes. Psychother Psychosom 2007 76 : 40 46.
10. Oquendo MA, Currier D, Mann JJ. Prospective studies of suicidal behavior in major depressive and bipolar disorders: what is the evidence for predictive risk factors? Acta Psychiatr Scand 2006 114 : 151 158.
11. Tollefson GD, Rampey AH Jr., Beasley CM Jr., Enas GG, Potvin JH. Absence of a relationship between adverse events and suicidality during pharmacotherapy for depression. J Clin Psychopharmacol 1994 14 : 163 169.
12. Henriques JB, Davidson RJ. Regional brain electrical asymmetries discriminate between previously depressed and healthy control subjects. J Abnorm Psychol 1990 99 : 22 31.
13. Debener S, Beauducel A, Nessler D, Brocke B, Heilemann H, Kayser J. Is resting anterior EEG alpha asymmetry a trait marker for depression? Findings for healthy adults and clinically depressed patients. Neuropsychobiology 2000 41 : 31 37.
14. Davidson RJ. Anterior cerebral asymmetry and the nature of emotion. Brain Cogn 1992 20 : 125 151.
15. Pizzagalli DA, Nitschke JB, Oakes TR et al. Brain electrical tomography in depression: the importance of symptom severity, anxiety, and melancholic features. Biol Psychiatry 2002 52 : 73 85.
16. Bruder GE, Stewart JW, Tenke CE et al. Electroencephalographic and perceptual asymmetry differences between responders and nonresponders to an SSRI antidepressant. Biol Psychiatry 2001 49 : 416 425.
17. Graae F, Tenke C, Bruder G et al. Abnormality of EEG alpha asymmetry in female adolescent suicide attempters. Biol Psychiatry 1996 40 : 706 713.
18. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured clinical interview for DSM-IV Axis I disorders - Patient edition (SCID-I/P). New York, NY : Biometrics Research Department, New York State Psychiatric Institute, 1996.
19. Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967 6 : 278 296.
20. Guy W (ed). ECDEU Assessment Manual for Psychopharmacology, revised. US Dept Health, Education and Welfare publication (ADM) 76-338. Rockville, MD : National Institute of Mental Health, 1976 : 218 222.
21. Knott VJ, Lapierre YD. Computerized EEG correlates of depression and antidepressant treatment. Prog Neuropsychopharmacol Biol Psychiatry 1987 11 : 213 221.
22. Kwon JS, Youn T, Jung HY. Right hemisphere abnormalities in major depression: quantitative electroencephalographic findings before and after treatment. J Affect Disord 1996 40 : 169 173.
23. Pollock VE, Schneider LS. Quantitative, waking EEG research on depression. Biol Psychiatry 1990 27 : 757 780.
24. Kinsbourne M. The biological determinants of functional bisymmetry and asymmetry. In : Kinsbourne M, ed. Asymmetrical Functions of the Brain. Cambridge : University Press, 1978 : 3 13.
25. Davidson RJ. Anterior electrophysiological asymmetries, emotion, and depression: conceptual and methodological conundrums. Psychophysiology 1998 35 : 607 614.
26. Urry HL, Nitschke JB, Dolski I et al. Making a life worth living: neural correlates of well-being. Psychol Sci 2004 15 : 367 372.
27. Bruder GE, Fong R, Tenke CE et al. Regional brain asymmetries in major depression with or without an anxiety disorder: a quantitative electroencephalographic study. Biol Psychiatry 1997 41 : 939 948.
28. Keller J, Nitschke JB, Bhargava T et al. Neuropsychological differentiation of depression and anxiety. J Abnorm Psychol 2000 109 : 3 10.
29. Hunter AM, Leuchter AF, Morgan ML, Cook IA, DeBrota DJ, Potter WZ. Neurophysiologic correlates of side effects in normal subjects randomized to venlafaxine or placebo. Neuropsychopharmacology 2005 30 : 792 799.
30. Cook IA, Leuchter AF, Morgan M et al. Early changes in prefrontal activity characterize clinical responders to antidepressants. Neuropsychopharmacology 2002 27 : 120 131.
31. Jick H, Kaye JA, Jick SS. Antidepressants and the risk of suicidal behaviors. JAMA 2004 292 : 338 343.