Canine anatomic phantom for preclinical dosimetry in internal emitter therapy

Journal of Nuclear Medicine

Volumn 49, Issue 3, 2008, Pages 446-452

  Padilla, Laura ^a   Lee, Choonsik ^a   Milner, Rowan ^b   Shahlaee, Amir ^c   Bolch, Wesley E ^a,b  

^a J Crayton Pruitt Family Department of Biomedical Engineering   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Canine phantom; NURBS models; Photon cross dose; Preclinical animal models; Radiation dosimetry

Indexed keywords

CONTRAST MEDIUM; RADIOPHARMACEUTICAL AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER PROGRAM; CONTROLLED STUDY; DOG; DOSE RESPONSE; DOSIMETRY; FLAME PHOTOMETRY; IMAGE QUALITY; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE;

ANIMALS; BODY BURDEN; COMPUTER SIMULATION; DOGS; DRUG EVALUATION, PRECLINICAL; MODELS, ANATOMIC; MODELS, BIOLOGICAL; PHANTOMS, IMAGING; RADIOMETRY; RADIOTHERAPY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RELATIVE BIOLOGICAL EFFECTIVENESS;

EID: 40449093971     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.046722     Document Type: Article

References (28)

1. Lindblad-Toh K, Wade CM, Mikkelsen TS, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 2005;438:803-819.
2. Starkey MP, Scase TJ, Mellersh CS, Murphy S. Dogs really are man's best friend: canine genomics has applications in veterinary and human medicine! Brief Funct Genomic Proteomic. 2005;4:112-128.
3. Vail DM, MacEwen EG. Spontaneously occurring tumors of companion animals as models for human cancer. Cancer Invest. 2000;18:781-792.
4. Khanna C, Lindblad-Toh K, Vail D, et al. The dog as a cancer model. Nat Biotechnol. 2006;24:1065-1066.
5. Hui TE, Fisher DR, Kuhn JA, et al. A mouse model for calculating cross-organ beta doses from yttrium-90-labeled immunoconjugates. Cancer. 1994;73:951-957.
6. Flynn AA, Green AJ, Pedley RB, Boxer GM, Boden R, Begent RH. A mouse model for calculating the absorbed beta-particle dose from (131)I- and (90)Y-labeled immunoconjugates, including a method for dealing with heterogeneity in kidney and tumor. Radiat Res. 2001;156:28-35.
7. Hindorf C, Ljungberg M, Strand SE. Evaluation of parameters influencing S values in mouse dosimetry. J Nucl Med. 2004;45:1960-1965.
8. Stabin MG, Peterson TE, Holburn GE, Emmons MA. Voxel-based mouse and rat models for internal dose calculations. J Nucl Med. 2006;47:655-659.
9. National Council on Radiation Protection and Measurements. Extrapolation of Radiation-Induced Cancer Risks from Nonhuman Experimental Systems. Bethesda, MD: National Council on Radiation Protection and Measurements; 2005. Report No. 150.
10. Sargan DR. IDID: inherited diseases in dogs - Web-based information for canine inherited disease genetics. Mamm Genome. 2004;15:503-506.
11. Patterson D. Companion animal medicine in the age of medical genetics. J Vet Intern Med. 2000;14:1-9.
12. Stabin MG. MIRDOSE: personal computer software for internal dose assessment in nuclear medicine. J Nucl Med. 1996;37:538-546.
13. Stabin MG, Sparks RB, Crowe E. OLINDA/EXM: the second-generation personal computer software for internal dose assessment in nuclear medicine. J Nucl Med. 2005;46:1023-1027.
14. Desrosiers MF, Avila MJ, Schauer DA, Coursey BM, Parks NJ. Experimental validation of radiopharmaceutical absorbed dose to mineralized bone tissue. Appl Radiat Isot. 1993;44:459-463.
15. Milner RJ, Dormehl IC, Louw WKA, Chaparro F, Kilian E. The biodistribution, pharmacokinetics, bone localization, and therapeutic effect of rhenium-188-HEDP in normal dogs and dogs with osteosarcoma of the appendicular skeleton [abstract]. Eur J Nucl Med. 1998;25:1109.
16. Louw WKA, Dormehl IC, Milner RJ, et al. Biodistribution of radiolabeled polymin-MP of different molecular sizes as a selective bone seeker for therapy in animal models [abstract]. Eur J Nucl Med. 1998;25:1167.
17. Milner RJ, Dormehl IC, Louw WKA, Kilian E. The biodistribution, pharmacokinetics, and bone localization of variously sized molecular radiolabeled polymin-MP in normal dogs and dogs with osteosarcoma of the appendicular skeleton [abstract]. Eur J Nucl Med. 1999;26:1120.
18. Stabin M. Nuclear medicine dosimetry. Phys Med Biol. 2006;51:R187-R202.
19. Cristy M, Eckerman KF. Specific Absorbed Fractions of Energy at Various Ages from Internal Photon Sources. Oak Ridge, TN: Oak Ridge National Laboratory; 1987. ORNL/TM-8381/volumes I-VII.
20. Segars WP. Development and Application of the New Dynamic NURBS-Based Cardiac-Torso (NCAT) Phantom [dissertation]. Chapel Hill, NC: University of North Carolina; 2001.
21. Segars WP, Lalush DS, Tsui BM. Modeling respiratory mechanics in the MCAT and spline-based MCAT phantom. IEEE Trans Nucl Sci. 2001;48:89-97.
22. Segars WP, Lalush DS, Tsui BMW. A realistic spline-based dynamic heart phantom. IEEE Trans Nucl Sci. 1999;46:503-506.
23. Segars WP, Tsui BM. Study of the efficacy of respiratory gating in myocardial SPECT using the new 4D NCAT phantom. IEEE Trans Nucl Sci. 2002;49:675-679.
24. International Commission on Radiological Protection. Basic Anatomical and Physiological Data for Use in Radiological Protection: Reference Values. Oxford, United Kingdom: Pergamon Press; 2002. Publication 89.
25. Miller ME. Anatomy of the Dog. Philadelphia, PA: W.B. Saunders Co.; 1993.
26. Kawrakow I. Accurate condensed history Monte Carlo simulation of electron transport. I. EGSnrc, the new EGS4 version. Med Phys. 2000;27:485-498.
27. Lee C, Lodwick D, Hasenauer D, Williams JL, Lee C, Bolch WE. Hybrid computational phantoms of the male and female newborn patient: whole-body models. Phys Med Biol. 2007;52:3309-3333.
28. Lee C, Lee C, Lodwick D, Bolch WE. NURBS-based 3-D anthropomorphic computational phantoms for radiation dosimetry applications. Radiat Prot Dosimetry. June 13, 2007 [Epub ahead of print].