Diagnostic value of serum chromogranin-A combined with MIBG scintigraphy in patients with adrenal incidentalomas

Quarterly Journal of Nuclear Medicine and Molecular Imaging

Volumn 52, Issue 1, 2008, Pages 84-88

  Giovanella, Luca ^a,b   Ceriani, L ^a   Balerna, M ^b   Keller, F ^b   Taborelli, M ^a   Marone, C ^c   Ferone, D ^d  

^a ONCOLOGY INSTITUTE OF SOUTHERN SWITZERLAND   (Switzerland)

^b Clinical Chemistry and Immunochemistry   (Switzerland)

^c Nephrology Regional Hospital   (Switzerland)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

Adrenal gland neoplasms; Catecholamines; Chromogranin A; Iodine; M iodobenzyl guanidine; Pheochromocytoma; Scintigraphy

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 123; CHROMOGRANIN A; CORTICOSTEROID;

ADRENAL INCIDENTALOMA; ADRENAL SCINTISCANNING; ADRENALECTOMY; ADULT; AGED; ARTICLE; CHROMAFFIN SYSTEM; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNORADIOMETRIC ASSAY; LAPAROSCOPIC SURGERY; MALE; PHEOCHROMOCYTOMA; PROTEIN BLOOD LEVEL; STEROIDOGENESIS; SYMPTOMATOLOGY;

3-IODOBENZYLGUANIDINE; ADOLESCENT; ADRENAL GLAND NEOPLASMS; ADULT; AGED; CHROMOGRANIN A; FEMALE; HUMANS; INCIDENTAL FINDINGS; MALE; MIDDLE AGED; PHEOCHROMOCYTOMA; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TUMOR MARKERS, BIOLOGICAL;

EID: 40449091072     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Kloos RT, Gross MD, Francis IR, Korobkin M, Shapiro B. Incidentally discovered adrenal masses. Endocr Rev 1995;16:460-84.
2. Plouin PF, Gimenez-Roqueplo AP, La Batide Alanore A, Salenave S, Duclos JM. Recent progress in the diagnosis, prognostic evaluation and treatment of pheochromocytoma. Rev Med Interne 2000;21:1075-85.
3. Baguet JP, Hammer L, Mazzuco TL, Chabre O, Mallion JM, Sturm N et al. Circumstances of discovery of phaeochromocytoma: a retrospective study of 41 patients. Eur J Endocrinol 2004;150:681-6.
4. NIH state-of-the science statement on management of the clinically inapparent adrenal mass ("incidentaloma"). NIH Consens State Sci Statements 2002;19:1-25.
5. Lenders JW, Eisenhofer G, Mannelli M, Pacak K. Phaeochromocytoma. Lancet 2005;366:665-75.
6. Gopan T, Remer E, Hamrahnian AH. Evaluating and managing adrenal incidentaloma. Cleve Clin j Med 2006;73:561-8.
7. Lenders JW, Pacak K, Walther MM, Linehan WM, Mannelli M, Friberg P et al. Biochemical diagnosis of pheochromocytoma: which test is the best? JAMA 2002;287:1427-34.
8. Sawka AM, Jaeschke R, Singh RJ, Young WE A comparison of biochemical tests for pheochromocytorna: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endorinol Metab 2003;88:553-8.
9. Lundberg GD. How clinicians should use the diagnostic laboratory in changing medical word. Clin Chim Acta 1999;280:3-11.
10. Eisenhofer G, Lenders JW, Goldstein DS, Mannelli M, Cszako G, Walther MM et al. Pheochromocytoma catecholamine phenotypes and prediction of tumor size and location by use of plasma free metanephrines. Clin Chem 2005;51:735-44.
11. Witteles RM, Kaplan EL, Roizen ME Sensitivity of diagnostic and localization tests for pheochromocytorna in clinical practice. Arch Intern Med 2000;160:2521-4.
12. Stridsberg M, Husebye ES. Chromogranin A and chromogranin B are sensitive circulating markers for phaeochromocytoma. Eur J Endocrinol 1997;136:67-73.
13. Tommasetti P, Mighori M, Simoni P, CAsadei R, De Iasio R, Corinaldesi R et al. Diagnostic value of plasma chromogranin A in neuroendocrine tumours. Eur J Gastroenterol Hepatol 2001;13:55-8.
14. Peracchi M, Conte D, Gebbia C, Penati C, Pizzinelli S, Arosio M et al. Plasma chromogranin A in patients with sporadic gastro-enteropancreatic neuroendocrine tumours or multiple endocrine neoplasia type 1. Eur J Endocrinol 2003;148:39-43.
15. Giovanella L, La Rosa S, Ceriani L, Uccella S, Garancini S. Chromogranin A as serum marker of neuroendocrine tumors: comparison with neuron-specific enolase and correlation with immunohistochemical findings. Int J Biol Markers 1999; 14:160-6.
16. Nobels FRE, Kwekkeboom DJ, Bouillon R, Lamberts SW. Chromogranin A: its clinical value as markers of neuroendocrine tumours. Eur J Clin Invest Endocrinol 1998;28:431-40.
17. Nobels FR, Kwekkeboom DJ, Coopmans W, Scheorimakers CH, Lindemans J, de Herder WW et al. Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuronspecific enolase and the alpha-subunit of glycoprotein hormones. J Clin Endocrinol Metab 1997;82:2622-8.
18. Giovanella L, Ceriani L. Serum chromogranin A immunoradiometric assay in the diagnosis of pheochromocytoma. Int J Biol Markers 2002;17:130-4.
19. Cotesta D, Caliumi C, Alo P, Petramala L, Reale MG, Masciangelo R et al. High plasma levels of human chromogranin A and adrenomedullin in patients with pheochromocytorna. Tumori 2005;91:53-8.
20. d'Herbomez M, Gouze V, Huglo D, Nocaudie M, Pattou F, Proye C et al. Chromogranin A assay and (131)I-MIBG scintigraphy for diagnosis and follow-up of pheochromocytoma. J Nucl Med 2001;42:993-7.
21. Grossrubatscher E, Dalino P, Vignati F, Gambacorta M, Pugliese R, Boniardi M et al. The role of chromogranin A in the management of patients with phaeochromocytonia. Clin Endocrinol 2006;65:287-93.
22. Giovanella L. Serum chromogranin A assay in differential diagnosis of incidentally discovered adrenal masses. Anticancer Res 2005;25:1547-50.
23. 123I-MIBG scan. Q J Nucl Med Mol Imaging 2006;50:344-7.
24. Degorce F, Goumon Y, Jacquemart L, Vidaud C, Bellanger L, Pons-Anicet D et al. A new human chromogranin A (CgA) immunoradiometric assay involving monoclonal antibodies raised against the unprocessed central domain (145-245). Br J Cancer 1999;79:65-71.
25. Unger N, Pitt C, Lopez Schmidt I, Walz MK, Schmid KW, Philipp T et al. Diagnostic value of various biochemical parameters for the diagnosis of pheochromocytoma in patients with adrenal mass. Eur J Endocrinol 2006;154:409-17.
26. Kasperlik-Zeluska AA, Roslonowska E, SLowinska-Srzednicka J, Migdalska B, Jeske W, Makowska A et al. Incidentally discovered adrenal mass (incidentaloma): investigation and management of 208 patients. Clin Endocrinol 1997;46:29-37.
27. Mantero F, Masini AM, Opocher G, Giovagnetti M, Arnaldi G. Adrenal incidentaloma: an overview of hormonal data from the National Italian Study Group. Horm. Res 1997;47:284-9.