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Volumn 44, Issue 4, 2008, Pages 486-487

QTc prolongation and/or oncology drug development: Who's in danger?

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; PACLITAXEL;

EID: 40449088851     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2008.01.013     Document Type: Note
Times cited : (4)

References (12)
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    • Food and Drug Administration International conference on harmonisation; Guidance on E14 - The clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs Fed Regist 70 2005 61134 61135
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    • Food and Drug Administration1
  • 2
    • 14544286345 scopus 로고    scopus 로고
    • Risks and benefits of phase 1 oncology trials, revisited
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    • Kurzrock, R.1    Benjamin, R.S.2
  • 3
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    • Trastuzumab-related cardiotoxicity: calling into question the concept of reversibility
    • M.L. Telli S.A. Hunt R.W. Carlson Trastuzumab-related cardiotoxicity: calling into question the concept of reversibility J Clin Oncol 25 2007 3525 3533
    • (2007) J Clin Oncol , vol.25 , pp. 3525-3533
    • Telli, M.L.1    Hunt, S.A.2    Carlson, R.W.3
  • 4
    • 0032209332 scopus 로고    scopus 로고
    • Paclitaxel and cardiotoxicity
    • E.A. Perez Paclitaxel and cardiotoxicity J Clin Oncol 16 1998 3481 3482
    • (1998) J Clin Oncol , vol.16 , pp. 3481-3482
    • Perez, E.A.1
  • 5
    • 40249094483 scopus 로고    scopus 로고
    • Drug-induced QTc interval prolongation: A proposal toward an efficient and safe anticancer drug development
    • G. Curigliano G. Spitaleri H. Fingert Drug-induced QTc interval prolongation: A proposal toward an efficient and safe anticancer drug development Eur J Cancer 44 2008 494 500
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  • 6
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    • Cardiac repolarization and the safety of new drugs defined by electrocardiography
    • J. Morganroth Cardiac repolarization and the safety of new drugs defined by electrocardiography Clin Pharmacol Ther 81 2007 108 113
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 108-113
    • Morganroth, J.1
  • 7
    • 44949177120 scopus 로고    scopus 로고
    • Risk management and eligibility criteria for QTc assessment in patients with advanced cancer
    • N. Sarapa X. Huang H. Fingert Risk management and eligibility criteria for QTc assessment in patients with advanced cancer Proc Amer Soc Clin Oncol 23 2005 203s (abstract 3047)
    • (2005) Proc Amer Soc Clin Oncol , vol.23 , pp. 203s
    • Sarapa, N.1    Huang, X.2    Fingert, H.3
  • 8
    • 0141576728 scopus 로고    scopus 로고
    • Baseline heart rate-corrected QT and eligibility for clinical trials in oncology
    • M. Varterasian M. Meyer H. Fingert Baseline heart rate-corrected QT and eligibility for clinical trials in oncology J Clin Oncol 21 2003 3378 3379
    • (2003) J Clin Oncol , vol.21 , pp. 3378-3379
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  • 9
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    • H. Fingert M. Varterasian Safety biomarkers and the clinical development of oncology therapeutics: Considerations for cardiovascular safety and risk management The AAPS Journal 8 2006 E89 E94
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    • Fingert, H.1    Varterasian, M.2
  • 10
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    • Cardiovascular safety profile of Combretastatin A4 phosphate in a single-dose phase I study in patients with advanced cancer
    • M.M. Cooney T. Radivoyevitch A. Dowlate Cardiovascular safety profile of Combretastatin A4 phosphate in a single-dose phase I study in patients with advanced cancer Clin Cancer Res 10 2004 96 100
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.