Capillary blood cell velocity in periulcerous regions of the lower leg measured by laser Doppler anemometry

Skin Research and Technology

Volumn 10, Issue 3, 2004, Pages 174-177

  Stücker, Markus ^a   Huntermann, Christina ^a   Bechara, Falk Georges ^a   Hoffmann, Klaus ^a   Altmeyer, Peter ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Blood flow; Capillary venous; Doppler; Laser; Leg ulcer; Microcirculation

Indexed keywords

PENTOXIFYLLINE; PROSTAGLANDIN E1; PROSTAVASIN;

ADULT; AGED; ANEMOMETRY; ARTICLE; BLOOD FLOW VELOCITY; CAPILLARY DENSITY; CAPILLARY FLOW; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ERYTHROCYTE KINETICS; FEMALE; HUMAN; HYPEREMIA; LEG ULCER; MALE; MICROCIRCULATION; QUANTITATIVE ANALYSIS; REST; SKIN ULCER; STATISTICAL SIGNIFICANCE; TRANSCUTANEOUS OXYGEN MONITORING;

AGED; AGED, 80 AND OVER; ALPROSTADIL; BLOOD FLOW VELOCITY; CAPILLARIES; CASE-CONTROL STUDIES; ERYTHROCYTES; FEMALE; HUMANS; LASER-DOPPLER FLOWMETRY; LEG; LEG ULCER; MALE; MIDDLE AGED; OXYGEN; PARTIAL PRESSURE; PENTOXIFYLLINE; VARICOSE ULCER;

EID: 4043179764     PISSN: 0909752X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0846.2004.00064.x     Document Type: Article

References (20)

1. Jünger M, Hahn M, Klyscz T, Steins A. Role of microangiopathy in the developement of venous leg ulcers. In: Messmer K, ed. Microcirculation in chronic venous insufficiency. Progress in applied microcirculation, Vol. 3. Basel: Karger, 1999: 180-193.
2. Bollinger A, Hoffmann U, Franzeck UK. Microvascular changes in arterial occlusive disease: target for pharmacotherapy. Vasc Med 1996; 1: 50-54.
3. Jull A, Waters J, Arroll B. Pentoxifylline for treatment of venous leg ulcers: a systematic review. Lancet 2002; 359: 1550-1554.
4. Colgan MP, Dormandy JA, Jones PW, Schraibman IG, Shanik DG, Young RAL. Oxpentifylline treatement of venous ulcers of the leg. BML 1990; 300: 972-975.
5. Thum J, Caspary L, Creutzig A, Alexander K. Intra-arterial and intravenous administration of prostaglandin E1 cause different changes to skin microcirculation in patients with peripheral arterial occlusive disease. VASA 1998; 27: 100-105.
6. Alt E. Development of radioligand assay for quantifying specific prostaglandin E1 binding in ischemic ulcers. Acta Med Austriaca 2000; 27: 152-155.
7. Bollinger A, Fagrell B. Clinical capillaroscopy. Toronto: Hogrefe and Huber Publishers, 1990.
8. Stücker M, Baier V, Reuther T, Hoffmann K, Kellam K, Altmeyer P. Capillary blood cell velocity in human skin capillaries located perpendicularly to the skin surface: measured by a new laser Doppler anemometer. Microvasc Res 1996; 52: 188-192.
9. Stücker M, Herde M, Baier V, Hoffmann K, Altmeyer P. Klinische Provokationsmanöver mit dem Laser Doppler Anemometer. Phlebologie 1998; 27: 152-158.
10. Johansson K, Jakobsson A, Lindahl K, Lindhagen J, Lundgren O, Nilsson GE. Influence of fibre diameter and probe geometry on the measuring depth of laser Doppler flowmetry in the gastrointestinal application. Int J Microcirc: Clin Exp 1991; 10: 219-229.
11. Fagrell B. Advances in microcirculation network evaluation: an update. Int J Microcirc Clin Exp 1995; 15 (Suppl. 1): 34-40.
12. Bollinger A, Hoffmann U, Franzeck UK. Evaluation of flux motion in man by the laser Doppler technique. Blood Vessels 1991; 28: 21-26.
13. Rooke TW. The use of transcutaneous oximetry in the noninvasive vascular laboratory. Int Angiol 1992; 11: 36-40.
14. Stücker M, Falkenberg M, Reuther T, Altmeyer P, Lübbers DW. Local oxygen content in the skin is increased in chronic venous incompetence. Microvasc Res 2000; 59: 99-106.
15. Acciavatti A, Laghi Pasini F, Capecchi PL, Messa GL, Lazzerini PE, De Giorgi L, Acampa M, Di Perri T. Effects of alprostadil on blood rheology and nucleoside metabolism in patients affected with lower limb chronic ischemia. Clin Hemorheol Microcirc 2001; 24: 49-57.
16. Bandiera G, Forletta M, Di paola FM, Cirielli C. PGE 1 short term therapy in critical lower limb ischemia. Int Angiology 2003; 22: 58-63.
17. 1 treatment of severe skin ischemia in patients with peripheral arterial insufficiency-the effect on skin microcirculation. VASA 1986; 15: 56-60.
18. Marchesi S, Pasqualini L, Lombardini R, Vaudo G, Lipattelli G, Pirro M, Schillaci G, Mannarino E. Prostaglandin E1 improves endothelial function in critical limb ischemia. J Cardiovasc Pharmacol 2003; 41: 249-253.
19. 2. New York: Thieme-Stratton, 1981.
20. De Sanctis MT, Belcaro G, Cesarone MR, Ippolito E, Nicolaides AN, Incandela L, Geroulakos G. Treatment of venous ulcers with pentoxifylline: a 12-month, double-blind, placebo controlled trial. Microcirculation and healing. Angiology 2002; 53 (Suppl. 1): 49-51.