Changes in the glutathione system of lung cell lines after treatment with hydrocortisone

Archives of Toxicology

Volumn 78, Issue 7, 2004, Pages 402-409

  Walther, Udo I ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Alveolar epithelial type II cells; ARDS; Glucocorticoids; Lung fibroblasts

Indexed keywords

ACETYLCYSTEINE; CYSTEINE; GLUCOCORTICOID; GLUTATHIONE; GLUTATHIONE REDUCTASE; HYDROCORTISONE;

ADULT RESPIRATORY DISTRESS SYNDROME; ANTIOXIDANT ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; ENZYME ACTIVITY; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL TYPE 2; LUNG FIBROBLAST; LUNG TOXICITY; PRIORITY JOURNAL; TREATMENT FAILURE;

EID: 4043179725     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-004-0557-0     Document Type: Article

References (39)

1. Ammon HPT, Müller PH, Eggstein M, Wintermantel C, Aigner B, Safayhi H, Stutzle M, Renn W (1992) Increase in glucose consumption by acetylcysteine during hyperglycemic clamp. A study with healthy volunteers. Drug Res 42:642-645
2. Baritussio A, Pettenazzo A, Benevento M, Alberti A, Gamba P (1992) Surfactant protein C is recycled from the alveoli to the lamellar bodies. Am J Physiol 263:L607-L611
3. Bernard GR, Luce JM, Sprung CL, Rinaldo JE, Tate RM, Sibbald WJ, Kariman K, Higgins S, Bradley R, Metz CA, Harris TR, Brigham KL (1987) High-dose corticoids in patients with the adult respiratory distress syndrome. N Engl J Med 317:1565-1570
4. Bernard GR, Wheeler AP, Arons MM, Morris PE, Paz HL, Russell JA, Wright PE, and the Antioxidant in ARDS Study Group (1997) A trial of antioxidants N-acetylcysteine and procysteine in ARDS. Chest 112:164-172
5. Bone R, Fisher C, Clemmer T, and the Methylprednisolone Severe Sepsis Study Group (1989) Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome. Chest 92:1032-1036
6. Bunnell E, Pacht ER (1993) Oxidized glutathione is increased in the alveolar fluid of patients with the adult respiratory distress syndrome. Am Rev Respir Dis 148:1174-1178
7. Burgunder JM, Varriale A, Lauterburg BH (1989) Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration. Eur J Clin Pharmacol 36:127-131
8. Cai J, Sun WM, Lu SC (1995) Hormonal and cell density regulation of hepatic y-glutamylcysteine synthetase gene expression. Mol Pharmacol 48:212-218
9. Cai J, Huang ZZ, Lu SC (1997) Differential regulation of γ-glutamycysteine synthetase heavy and light subunit gene expression. Biochem J 326:167-172
10. Chobert MN, Grondin G, Brouillet A, Laperche Y, Beaudoin AR (1996) Control of γ-glutamyl transpeptidase expression by glucocorticoids in the rat pancreas. J Biol Chem 271:12431-12437
11. Crapo JD, Barry BE, Gehr P, Bachofen M, Weibel ER (1982) Cell number and cell characteristics of normal human lung. Am Rev Respir Dis 125:740-745
12. Domenighetti G, Quattropani, C Schaller MD (1999) N-acetylcysteine and acute lung injury. Rev Mal Respir 16:29-37
13. Goldberg DM, Spooner RJ (1987) Glutathione reductase. NAD(P)H: oxidized glutathione oxidoreductase (EC 1.6.4.2). In: Bergmeyer HU, Bergmeyer J, Grassl M (eds) Methods of enzymatic analysis, vol III, VCH, Weinheim, pp258-265
14. Helm KU, Renovanz H-D, Schmahl K, v Clarmann M (1971) Die Zinknebelvergiftung und ihre Behandlung. I. Chemische und toxikologische Grundlagen. Wehrmed Monatsschrift 15:1-6
15. Hjortsø E, Qvist J, Bud MI, Thomsen JL, Andersen JB, Wiberg-Jørgensen F, Jensen NK, Jones R, Reid MM, Zapol WM (1988) ARDS after accidental inhalation of zinc chloride smoke. Intensive Care Med 14:17-24
16. Huang CS, Anderson ME, Meister A (1993) Amino acid sequence and function of the light subunit of rat kidney γ-glutamylcysteine synthetase. J Biol Chem 268:20578-20583
17. Jepsen S, Herlevsen P, Knudsen P, Bud MI, Klausen NO (1992) Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: a prospective, randomized, placebo-controlled study. Crit Care Med 20:918-923
18. Laurent T, Markert M, Feihl F, Schaller MD, Perret C (1996) Oxidant-antioxidant balance in granulocytes during ARDS. Effect of N-acetylcysteine. Chest 109:163-166
19. Lee JW, Iwatsuru M, Nishigori H (1998) Alteration of activities of hepatic antioxidant defence enzymes in developing chick embryos after glucocorticoid administration - a factor to produce some adverse effects? J Pharm Pharmacol 50:655-660
20. Lu SC, Ge JL, Kuhlenkamp, J Kaplowitz N (1992) Insulin and glucocorticoid dependence of hepatic γ-glutamylcysteine synthetase and glutathione synthesis in the rat. Studies in cultured hepatocytes and in vivo. J Clin Invest 90:524-532
21. Luhr OR, Antonsen K, Karlsson M, Aardal S, Thorsteinsson A, Forstell CG, Bonde J, and the ARF Study Group (1999) Incidence and mortality after acute respiratory failure and acute respiratory distress syndrome in Sweden, Denmark and Iceland. Am J Respir Crit Care Med 159:1849-1861
22. Meduri GU, Kanangat S (1998) Glucocorticoid treatment of sepsis and acute respiratory distress syndrome: time for a critical reappraisal. Crit Care Med 26:630-633
23. Millar BC, Jinks S (1985) Studies on the relationship between the radiation resistance and glutathione content of human and rodent cells after treatment with dexamethasone in-vitro. Int J Rad Biol 47:539-552
24. Mize CE, Langdon RG (1962) Hepatic glutathione reductase. J Biol Chem 237:1589-1595
25. Moss M, Guidot DM, Wong LM, Hoor TT, Perez RL, Brown LAS (2000) The effects of chronic alcohol abuse on pulmonary glutathione homeostasis. Am J Respir Crit Care Med 161:414-419
26. Ortolani O, Conti A, DeGaudio AR, Masoni M, Novelli G (2000) Protective effects of N-acetylcysteine and rutin on the lipid peroxidation of the lung epithelium during the adult respiratory distress syndrome. Shock 13:14-18
27. Rahman I, Antonicelli F, MacNee W (1999) Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-α and dexamethasone in human alveolar epithelial cells. J Biol Chem 274:5088-5096
28. Read SM, Northcote DH (1981) Minimization of variation in the response to different proteins of the Coomassie Blue G dyebinding assay for protein. Anal Biochem 116:53-64
29. Reed DJ (1990) Glutathione: toxicological implications. Annu Rev Pharmacol Toxicol 30:603-631
30. Setogawa T, Kosano H, Ogihara-Umeda I, Kayanuma T, Nishigori H (1994) Preventive effect of SA3443, a novel cyclic disulfide, on glucocorticoid-induced cataract formation of developing chick embryo. Exp Eye Res 58:689-695
31. Steinebach OM, Wolterbeek HT (1993) Effects of zinc on rat hepatoma HTC cells and primary cultured rat hepatocytes. Toxicol Appl Pharmacol 118:245-254
32. Suter PM, Domenighetti G, Schaller MD, Laverriere MC, Ritz R, Perret C (1994) N-Acetylcysteine enhances recovery from acute lung injury in man: a randomized, double-blind, placebo-controlled clinical study. Chest 105:190-194
33. Tietze F (1969) Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 27:502-522
34. Walmrath D, Guenther A, Grimminger F, Seeger W (2000) The alveolar surfactant system, it's pathogenetic significance in acute lung failure (ARDS) and therapeutic perspectives. Intensivmed Notfallmed 37:307-317
35. Walther UI, Mückter H, Fichtl B, Forth W (1999a) Effect of hydrocortisone pretreatment on decreased protein synthesis in various lung cells after zinc chloride incubation. In Vitro Mol Toxicol 12: 109-117
36. Walther UI, Mückter H, Fichtl B, Forth W (1999b) Influence of glutathione on zinc-mediated cellular toxicity. Biol Trace Elem Res 67:97-107
37. Walther UI, Wilhelm B, Walther SC, Mückter H, Fichtl B (2000) Zinc toxicity in various lung cell lines is mediated by glutathione and GSSG reductase activity. Biol Trace Elem Res 78:163-177
38. Wolff JEA, Denecke J, Jürgens H (1996) Dexamethasone induces partial resistance to cisplatinum in C6 glioma cells. Anticancer Res 16:805-810
39. Zimmerman GA, Albertine KH, Carveth HJ, Gill EA, Grissom CK, Hoidal JR, Imaizumi T, Maloney CG, Maclntyre TM, Michael JR, Orme JF, Prescott SM, Topham MS (1999) Endothelial activation in ARDS. Chest 116:18S-24S