Upregulation of S100A4 after spinal cord transection in adult rats

Acta Pharmacologica Sinica

Volumn 25, Issue 8, 2004, Pages 1007-1012

  Zhang, Kai Hua ^a   Han, Shu ^a   Lu, Pei Hua ^a   Xu, Xiao Ming ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b University of Louisville School of Medicine   (United States)

Author keywords

Gene expression; S100A4; Spinal cord injury

Indexed keywords

CALVASCULIN; PROTEIN S 100; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; NONHUMAN; NORTHERN BLOTTING; PROTEIN LOCALIZATION; RAT; SPINAL CORD TRANSSECTION; UPREGULATION;

ANIMALS; ASTROCYTES; FEMALE; GENE EXPRESSION REGULATION; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; S100 PROTEINS; SPINAL CORD; SPINAL CORD INJURIES; UP-REGULATION;

EID: 4043175492     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Donato R. S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol 2001; 33: 637-68.
2. Barraclough R. Calcium-binding protein S100A4 in health and disease. Biochim Biophys Acta 1998; 1448: 190-9.
3. Sherbet GV, Lakshmi MS. S100A4 (MTS1) calcium binding protein in cancer growth, invasion and metastasis. Anticancer Res 1998; 18: 2415-21.
4. Grigorian MS, Tulchinsky EM, Zain S, Ebralidze AK, Kramerov DA, Kriajevska MV, et al. The mts1 gene and control of tumor metastasis. Gene 1993; 135: 229-38.
5. Gupta S, Hussain T, MacLennan GT, Fu P, Patel J, Mukhtar H. Differential expression of S100A2 and S100A4 during progression of human prostate adenocarcinoma. J Clin Oncol 2003; 21: 106-12.
6. Wroblewski R, Roomans GM, Kozlova EN. Effects of dorsal root transection on morphology and chemical composition of degenerating nerve fibers and reactive astrocytes in the dorsal funiculus. Exp Neurol 2000; 164: 236-45.
7. Kozlova EN, Lukanidin E. Metastasis-associated mts1 (S100A4) protein is selectively expressed in white matter astrocytes and is up-regulated after peripheral nerve or dorsal root injury. Glia 1999; 27: 249-58.
8. Novitskaya V, Grigorian M, Kriajevska M, Tarabykina S, Bronstein I, Berezin V, et al. Oligomeric forms of the metastasis-related Mts1 (S100A4) protein stimulate neuronal differentiation in cultures of rat hippocampal neurons. J Biol Chem 2000; 275: 41278-86.
9. Xu XM, Guenard V, Kleitman N, Aebischer P, Bunge MB. A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Exp Neurol 1995; 134: 261-72.
10. Xu XM, Guenard V, Kleitman N, Bunge MB. Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J Comp Neurol 1995; 351: 145-60.
11. Xiao HS, Huang QH, Zhang FX, Bao L, Lu YJ, Guo C, et al. Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain. Proc Natl Acad Sci USA 2002; 99: 8360-5.
12. Duarte WR, Iimura T, Takenaga K, Ohya K, Ishikawa I, Kasugai S. Extracellular role of S100A4 calcium-binding protein in the periodontal ligament. Biochem Biophys Res Commun 1999; 255: 416-20.
13. Watanabe Y, Usuda N, Tsugane S, Kobayashi R, Hidaka H. Calvasculin, an encoded protein from mRNA termed pEL-98, 18A2, 42A, or p9Ka, is secreted by smooth muscle cells in culture and exhibits Ca(2+)-dependent binding to 36-kDa microfibril-associated glycoprotein. J Biol Chem 1992; 267: 17136-40.