U-serrated immunodeposition pattern differentiates type VII collagen targeting bullous diseases from other subepidermal bullous autoimmune diseases

British Journal of Dermatology

Volumn 151, Issue 1, 2004, Pages 112-118

  Vodegel, R M ^a   Jonkman, M F ^a   Pas, H H ^a   De Jong, M C J M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Direct immunofluorescence microscopy; Epidermolysis bullosa acquisita; Pemphigoid; Serrated

Indexed keywords

COLLAGEN TYPE 7; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

ARTICLE; AUTOIMMUNE DISEASE; BULLOUS SKIN DISEASE; CONTROLLED STUDY; DIAGNOSTIC ERROR; FEMALE; HEMIDESMOSOME; HUMAN; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOGLOBULIN A DEFICIENCY; MALE; MOLECULAR RECOGNITION; MUCOUS MEMBRANE PEMPHIGOID; PEMPHIGOID; PRIORITY JOURNAL; SKIN BIOPSY;

BASEMENT MEMBRANE; COLLAGEN TYPE VII; DIAGNOSIS, DIFFERENTIAL; EPIDERMOLYSIS BULLOSA ACQUISITA; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMMUNOBLOTTING; MICROSCOPY, IMMUNOELECTRON; PRECIPITIN TESTS; SKIN; SKIN DISEASES, VESICULOBULLOUS;

EID: 4043171965     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2004.06006.x     Document Type: Article

References (21)

1. de Jong MCJM, Bruins S, Heeres K et al. Bullous pemphigoid and epidermolysis bullosa acquisita: differentiation by fluorescence overlay antigen mapping. Arch Dermatol 1996; 132: 151-7.
2. Powell AM, Black M. A stepwise approach to the diagnosis of blisters in the clinic (1). Clin Dermatol 2001; 19: 598-606.
3. Morrison LH. Direct immunofluorescence microscopy in the diagnosis of autoimmune bullous dermatoses. Clin Dermatol 2001; 19: 607-13.
4. Kanitakis J. Indirect immunofluorescence microscopy for the serological diagnosis of autoimmune blistering skin diseases: a review. Clin Dermatol 2001; 19: 614-21.
5. Pas HH. Immunoblot assay in differential diagnosis of autoimmune blistering skin diseases. Clin Dermatol 2001; 19: 622-30.
6. Zillikens D, Kawahara Y, Ishiko A et al. A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone [corrected and republished in J Invest Dermatol 1996; 106: 1333-8]. J Invest Dermatol 1996; 106: 465-70.
7. Egan CA, Yee C, Zillikens D et al. Anti-p200 pemphigoid: diagnosis and treatment of a case presenting as an inflammatory subepidermal blistering disease. J Am Acad Dermatol 2002; 46: 786-9.
8. Vodegel RM, de Jong MCJM, Pas HH et al. Anti-epiligrin cicatricial pemphigoid and epidermolysis bullosa acquisita: differentiation by use of indirect immunofluorescence microscopy. J Am Acad Dermatol 2003; 48: 542-7.
9. Gammon WR, Briggaman RA, Inman AO et al. Differentiating anti-lamina lucida and anti-sublamina densa anti-BMZ antibodies by indirect immunofluorescence on 1.0 M sodium chloride separated skin. J Invest Dermatol 1984; 82: 139-44.
10. Gammon WR, Briggaman RA, Wheeler C Jr. Epidermolysis bullosa acquisita presenting as an inflammatory bullous disease. J Am Acad Dermatol 1982; 7: 382-7.
11. Domloge-Hultsch N, Gammon WR, Briggaman RA et al. Epiligrin, the major human keratinocyte integrin ligand, is a target in both an acquired autoimmune and an inherited subepidermal blistering skin disease. J Clin Invest 1992; 90: 1628-33.
12. Vodegel RM, Kiss M, de Jong MCJM et al. The use of skin substrates deficient in basement membrane molecules for the diagnosis of autoimmune bullous disease. Eur J Dermatol 1998; 8: 83-5.
13. Vodegel RM, de Jong MCJM, Pas HH, Jonkman MF. IgA-mediated epidermolysis bullosa acquisita: two cases and review of the literature. J Am Acad Dermatol 2002; 47: 919-25.
14. Lazarova Z, Yancey KB. Reactivity of autoantibodies from patients with defined subepidermal bullous diseases against 1 mol/L salt-split skin. Specificity, sensitivity, and practical considerations. J Am Acad Dermatol 1996; 35: 398-403.
15. Jonkman MF, Schuur J, Dijk F et al. Inflammatory variant of epidermolysis bullosa acquisita with IgG autoantibodies against type VII collagen and laminin alpha3. Arch Dermatol 2000; 136: 227-31.
16. Gammon WR. Epidermolysis bullosa acquisita: a disease of autoimmunity to type VII collagen. J Autoimmun 1991; 4: 59-71.
17. Kirtschig G, Marinkovich MP, Burgeson RE, Yancey KB. Anti-basement membrane autoantibodies in patients with anti-epiligrin cicatricial pemphigoid bind the alpha subunit of laminin 5. J Invest Dermatol 1995; 105: 543-8.
18. Masunaga T, Shimizu H, Ishiko A, Nishikawa T. Evaluation of immunoelectron microscopic techniques in the study of basement membrane antigens. Histochem Cell Biol 1998; 110: 107-11.
19. Vaillant L, Bernard P, Joly P et al. Evaluation of clinical criteria for diagnosis of bullous pemphigoid. French Bullous Study Group. Arch Dermatol 1998; 134: 1075-80.
20. Briggaman RA, Gammon WR, Woodley DT. Epidermolysis bullosa acquisita of the immunopathological type (dermolytic pemphigoid). J Invest Dermatol 1985; 85: 79-84s.
21. Gammon WR, Briggaman RA, Woodley DT et al. Epidermolysis bullosa acquisita - a pemphigoid-like disease. J Am Acad Dermatol 1984; 11: 820-32.