An efficient synthesis of lactacystin β-lactone

Angewandte Chemie - International Edition

Volumn 43, Issue 17, 2004, Pages 2293-2296

  Donohoe, Timothy J ^a   Sintim, Herman O ^a   Sisangia, Leena ^a   Harling, John D ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Aldol reaction; Heterocycles; Natural products; Reduction; Total synthesis

Indexed keywords

AMMONIA; CHEMICAL REACTIONS; ORGANIC COMPOUNDS;

ALDOL REACTIONS; LACTACYSTIN; PYRROLES;

SYNTHESIS (CHEMICAL);

LACTACYSTIN BETA LACTONE; PROTEASOME INHIBITOR; ACETYLCYSTEINE; DRUG DERIVATIVE; LACTACYSTIN; LACTACYSTIN BETA-LACTONE; LACTONE; RUTHENIUM;

ALDOL REACTION; ARTICLE; DERIVATIZATION; DRUG SYNTHESIS; METHYLATION; QUANTUM YIELD; REACTION ANALYSIS; REDUCTION; STEREOCHEMISTRY; CHEMISTRY; SYNTHESIS;

ACETYLCYSTEINE; LACTONES; RUTHENIUM;

EID: 4043159247     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200453843     Document Type: Article

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