Regioselective C-alkylation of alkyl 4-hydroxy-2-methylthiophene-3- carboxylates with α-halo ketones

Russian Chemical Bulletin

Volumn 53, Issue 3, 2004, Pages 631-634

  Krayushkin, M M ^a   Shirinian, V Z ^a   Nikalin, D M ^a   Shimkin, A A ^a  

^a N D ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

Author keywords

halo ketones; alkylation; hydroxythiophene

Indexed keywords

CARBON; CARBOXYLIC ACID DERIVATIVE; KETONE DERIVATIVE; OXYGEN; SOLVENT; THIOPHENE DERIVATIVE;

ALKYLATION; ARTICLE; SYNTHESIS;

EID: 4043154921     PISSN: 10665285     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:RUCB.0000035648.41262.77     Document Type: Article

References (18)

1. S. Gronowitz and A.-B. Hörnfeldt, in The Chemistry of Heterocyclic Compounds: Thiophene and Its Derivatives, Ed. S. Gronowitz, Wiley, New York, 1986, Vol. 44, Part 2, Ch. 1.
2. B. Capon and F. C. Kwok, J. Am. Chem. Soc., 1989, 111, 5346.
3. J. Scramstad, A. Lunde, H. Hope, V. Bjørnstad, and P. Frøyen, J. Chem. Soc., Perkin Trans. 2, 2000, 1453.
4. G. A. Hurter and H. McNab, J. Chem. Soc., Chem. Commun., 1990, 375.
5. Y. Zhang, A.-B. Hörnfeldt, and S. Gronowitz, J. Heterocycl. Chem., 1993, 30, 129.
6. G. A. Hunter, Diss. Abstr. Int. B, 1992, 52, 5827; Chem. Abstr., 1993, 118, 124340k.
7. G. A. Hunter, Diss. Abstr. Int. B, 1992, 52, 5827; Chem. Abstr., 1993, 118, 124340k.
8. R. Lantz and A.-B. Hörnfeldt, Chem. Scripta, 1976, 10, 126.
9. A. Merz and C. Rem, J. Prakt. Chem. (Chem-Ztg.), 1996, 338, 672.
10. (a) E. B. Pedersen and S.-O. Lawesson, Tetrahedron, 1971, 27, 3861;
11. (b) E. B. Pedersen and S.-O. Lawesson, Tetrahedron, 1972, 28, 2479.
12. (a) B. Cederlund and A.-B. Hörnfeldt, Chem. Scripta, 1975, 8, 140;
13. (b) B. Cederlund and A.-B. Hörnfeldt, Acta Chem. Scand., 1971, 25, 3546;
14. (c) B. Cederlund and A.-B. Hornfeldt, Acta Chem. Scand., 1971, 25, 3657;
15. (d) B. Cederlund and A.-B. Hörnfeldt, Acta Chem. Scand., 1971, 25, 3324.
16. E. Benary and A. Baravian, Chem. Ber., 1915, 48, 593.
17. R. Justoni, Chim. Ind. (Italy), 1942, 24, 195; Chem. Abstr., 1944, 38, 3610.
18. R. Justoni, Chim. Ind. (Italy), 1942, 24, 195; Chem. Abstr., 1944, 38, 3610.