Subtle disruption of the middle cerebellar peduncles in patients with Schizophrenia

Neuropsychobiology

Volumn 50, Issue 2, 2004, Pages 119-123

  Okugawa, Gaku ^a   Nobuhara, Kenji ^a   Minami, Tomohisa ^a   Tamagaki, Chiharu ^a   Takase, Katsunori ^a   Sugimoto, Tatsuya ^a   Sawada, Satoshi ^a   Kinoshita, Toshihiko ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Averaged diffusion coefficient; Cerebellar peduncle; Cerebellum; Diffusion tensor imaging; Fractional anisotropy; Schizophrenia

Indexed keywords

NEUROLEPTIC AGENT;

ADULT; ANISOTROPY; ARTICLE; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIFFUSION TENSOR IMAGING; FEMALE; HUMAN; IMAGE ANALYSIS; MALE; MEASUREMENT; MENTAL PATIENT; MIDDLE CEREBELLUM PEDUNCLE; PRIORITY JOURNAL; SCHIZOPHRENIA;

ADULT; ALGORITHMS; ANISOTROPY; ANTIPSYCHOTIC AGENTS; CEREBELLUM; FEMALE; FUNCTIONAL LATERALITY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA;

EID: 4043145961     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000079101     Document Type: Article

References (23)

1. Andreasen NC, O'Leary DS, Cizadlo T, Arndt S, Rezai K, Ponto LLB, Watkins GL, Hichwa RD: Schizophrenia and cognitive dysmetria: A positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry. Proc Natl Acad Sci USA 1996;93:9985-9990.
2. Schultz SK, Andreasen NC: Schizophrenia. Lancet 1999;353:1425-1430.
3. Okugawa G, Sedvall G, Nordstrom M, Andreasen N, Pierson R, Magnotta V, Agartz I: Selective reduction of the posterior superior vermis in men with chronic schizophrenia. Schizophr Res 2002;55:61-67.
4. Okugawa G, Sedvall GC, Agartz I: Smaller cerebellar vermis but not hemisphere volumes in patients with chronic schizophrenia. Am J Psychiatry 2003;160:1614-1617.
5. Okugawa G, Sedvall G, Agartz I: Reduced grey and white matter volumes in the temporal lobe of male patients with chronic schizophrenia. Eur Arch Psychiatry Clin Neurosci 2002;252:120-123.
6. Ito M: The Cerebellum and Neural Control. New York, Raven Press, 1984.
7. Markis N, Worth AJ, Sorensen AG, Papadimitriou GM, Wu O, Reese TG, Wedeen VJ, Davis TL, Stakes JW, Caviness VS, Kaplan E, Rosen BR, Pandya DN, Kennedy DN: Morphometry of in vivo human white matter association pathways with diffusion-weighted magnetic resonance imaging. Ann Neurol 1997;42:951-962.
8. Bihan DL, Mangin J, Poupon C, Clark CA, Pappata S, Molko N, Chabriat H: Diffusion tensor imaging: Concepts and applications. J Magn Reson Imaging 2001;13:534-546.
9. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, ed 4, rev. Washington, American Psychiatric Association, 2000.
10. American Psychiatric Association: Practice guideline for the treatment of patients with schizophrenia. Am J Psychiatry 1997;154:1-63.
11. Kay SR, Fiszbein A, Opler LA: The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 1987;13:261-276.
12. Spitzer RL, Willams JBW, Gibbson M, First M: The structured clinical interview for DSM-III-R Non-Patient Edition (SCID-NP). Washington, American Psychiatric Association, 1990.
13. Spitzer RL, William JBW, Gibbson M, First M: The structured clinical interview for DSM-III-R (SCID). Washington, American Psychiatric Association, 1990.
14. Basser PJ, Pierpaoli C: Microstructural features and physiological features of tissue elucidated by quantitative diffusion tensor MRI. J Magn Reson 1996;111:209-219.
15. Wang F, Sun Z, Du X, Wang X, Cong Z, Zhang H, Zang D, Hong N: A diffusion tensor imaging study of middle and superior cerebellar peduncle in male patients with schizophrenia. Neurosci Lett 2003;348:135-138.
16. Shrout P, Fleiss J: Intraclass correlations uses in assessing rater reliability. Psychol Bull 1979;86:420-429.
17. Lim KO, Hedehus M, Moseley M, de Crespigny A, Sullivan EV, Pfefferbaum A: Compromised white matter tract integrity in schizophrenia inferred from diffusion tensor imaging. Arch Gen Psychiatry 1999;56:367-374.
18. Foong J, Maier M, Clark CA, Barker GJ, Miller DH, Ron MA: Neuropathological abnormalities of the corpus callosum in schizophrenia: A diffusion tensor imaging study. J Neurol Neurosurg Psychiatry 2000;68:242-244.
19. Agartz I, Andersson JLR, Skare S: Abnormal brain white matter in schizophrenia: A diffusion tensor imaging study. Neuroreport 2001;12:2251-2254.
20. Kubicki M, Westin CF, Maier SE, Frumin M, Nestor PG, Salisbury DF, Kikinis R, Jolesz FA, McCarley RW, Shenton ME: Uncinate fasciculus findings in schizophrenia: A magnetic resonance diffusion tensor imaging study. Am J Psychiatry 2002;159:813-820.
21. Buchsbaum MS, Tang CY, Peled S, Gudbjartsson H, Lu D, Hazlett EA, Downhill J, Jaznedar M, Fallon JH, Atlas SW: MRI white matter diffusion anisotropy and PET metabolic rate in schizophrenia. Neuroreport 1998;9:425-430.
22. Hoptman MJ, Volavka J, Johnson G, Weiss E, Bilder RM, Lim KO: Frontal white matter microstructure, aggression, and impulsivity in men with schizophrenia: A preliminary study. Biol Psychiatry 2000;52:9-14.
23. Minami T, Nobuhara K, Okugawa G, Takase K, Yoshida T, Sawada S., Ha-Kawa S, Ikeda K, Kinoshita T: Diffusion tensor MR imaging of disruption of regional white matter in schizophrenia. Neuropsychobiology 2003;47:141-145.