메뉴 건너뛰기




Volumn 34, Issue 1, 2004, Pages 442-453

Endothelin and pulmonary arterial hypertension

Author keywords

bosentan; endothelin; endothelin receptor antagonist; Pulmonary hypertension

Indexed keywords

BERAPROST; BOSENTAN; ENDOTHELIN; ILOPROST; PROSTACYCLIN; SILDENAFIL; UNIPROST; VASODILATOR AGENT;

EID: 4043113533     PISSN: 00490172     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2003.11.003     Document Type: Article
Times cited : (28)

References (90)
  • 1
    • 0013543367 scopus 로고
    • The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes
    • Inoue A., Yanagisawa M., Kimura S., Kasuya Y., Miyauchi T., Goto K., et al. The human endothelin family Three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci U S A. 86:1989;2864-2867
    • (1989) Proc Natl Acad Sci U S a , vol.86 , pp. 2864-2867
    • Inoue, A.1    Yanagisawa, M.2    Kimura, S.3    Kasuya, Y.4    Miyauchi, T.5    Goto, K.6
  • 2
    • 0023859136 scopus 로고
    • A novel potent vasoconstrictor peptide produced by vascular endothelial cells
    • Yanagisawa M., Kurihara H., Kimura S., Goto K., Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 332:1988;411-415
    • (1988) Nature , vol.332 , pp. 411-415
    • Yanagisawa, M.1    Kurihara, H.2    Kimura, S.3    Goto, K.4    Masaki, T.5
  • 3
    • 0036140090 scopus 로고    scopus 로고
    • Endothelin-1 and endothelin receptor antagonists as potential cardiovascular therapeutic agents
    • Ergul A. Endothelin-1 and endothelin receptor antagonists as potential cardiovascular therapeutic agents. Pharmacotherapy. 22:2002;54-65
    • (2002) Pharmacotherapy , vol.22 , pp. 54-65
    • Ergul, A.1
  • 4
    • 0031829004 scopus 로고    scopus 로고
    • Endothelin as a regulator of cardiovascular function in health and disease
    • Haynes W.G., Webb D.J. Endothelin as a regulator of cardiovascular function in health and disease. J Hypertens. 16:1998;1081-1098
    • (1998) J Hypertens , vol.16 , pp. 1081-1098
    • Haynes, W.G.1    Webb, D.J.2
  • 6
    • 0028358673 scopus 로고
    • Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch
    • McArthur H., Warner T.D., Wood E.G., Corder R., Vane J.R. Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch. Biochem Biophys Res Commun. 200:1994;395-400
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 395-400
    • McArthur, H.1    Warner, T.D.2    Wood, E.G.3    Corder, R.4    Vane, J.R.5
  • 7
    • 0026699032 scopus 로고
    • Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium
    • Malek A., Izumo S. Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium. Am J Physiol. C263:1992;389-396
    • (1992) Am J Physiol , vol.263 , pp. 389-396
    • Malek, A.1    Izumo, S.2
  • 8
    • 0032005875 scopus 로고    scopus 로고
    • Reduced extracellular pH increases endothelin-1 secretion by human renal micro-vascular endothelial cells
    • Wesson D., Simoni J., Green D.F. Reduced extracellular pH increases endothelin-1 secretion by human renal micro-vascular endothelial cells. J Clin Invest. 101:1998;578-583
    • (1998) J Clin Invest , vol.101 , pp. 578-583
    • Wesson, D.1    Simoni, J.2    Green, D.F.3
  • 9
    • 0032433193 scopus 로고    scopus 로고
    • Prolonged exercise causes an increase in endothelin-1 production in the heart in rats
    • Maeda S., Miyauchi T., Sakai S., Kobayashi T., Iemitsu M., Goto K., et al. Prolonged exercise causes an increase in endothelin-1 production in the heart in rats. Am J Physiol. H275:1998;2105-2112
    • (1998) Am J Physiol , vol.275 , pp. 2105-2112
    • Maeda, S.1    Miyauchi, T.2    Sakai, S.3    Kobayashi, T.4    Iemitsu, M.5    Goto, K.6
  • 11
    • 0026534718 scopus 로고
    • Oxidized low-density lipoproteins induce mRNA expression and release of endothelin from human and porcine endothelium
    • Boulanger C.M., Tanner F.C., Bea M.L., Hahn A.W., Werner A., Luscher T.F. Oxidized low-density lipoproteins induce mRNA expression and release of endothelin from human and porcine endothelium. Circ Res. 70:1992;1191-1197
    • (1992) Circ Res , vol.70 , pp. 1191-1197
    • Boulanger, C.M.1    Tanner, F.C.2    Bea, M.L.3    Hahn, A.W.4    Werner, A.5    Luscher, T.F.6
  • 12
    • 0026088465 scopus 로고
    • Effects of glucose and insulin on immunoreactive endothelin-1 release from cultured bovine endothelial cells
    • Hattori Y., Kasai K., Nakamura T., Emodo T., Shimoda S.I. Effects of glucose and insulin on immunoreactive endothelin-1 release from cultured bovine endothelial cells. Metabolism. 40:1991;165-169
    • (1991) Metabolism , vol.40 , pp. 165-169
    • Hattori, Y.1    Kasai, K.2    Nakamura, T.3    Emodo, T.4    Shimoda, S.I.5
  • 13
    • 0025869172 scopus 로고
    • Hirudin and nitrates inhibit the thrombin-induced release of endothelin from the intact porcine aorta
    • Boulanger C.M., Luscher T.F. Hirudin and nitrates inhibit the thrombin-induced release of endothelin from the intact porcine aorta. Circ Res. 68:1991;1768-1772
    • (1991) Circ Res , vol.68 , pp. 1768-1772
    • Boulanger, C.M.1    Luscher, T.F.2
  • 14
    • 0026566370 scopus 로고
    • Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells
    • Imai T., Hirata Y., Emori T., Yanagisawa M., Masaki T., Marumo F. Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells. Hypertension. 19:1992;753-757
    • (1992) Hypertension , vol.19 , pp. 753-757
    • Imai, T.1    Hirata, Y.2    Emori, T.3    Yanagisawa, M.4    Masaki, T.5    Marumo, F.6
  • 15
    • 0031878495 scopus 로고    scopus 로고
    • Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression
    • Matsuura A., Yamochi W., Hirata K., Kawashima S., Yokoyama M. Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression. Hypertension. 32:1998;89-95
    • (1998) Hypertension , vol.32 , pp. 89-95
    • Matsuura, A.1    Yamochi, W.2    Hirata, K.3    Kawashima, S.4    Yokoyama, M.5
  • 16
    • 0032959132 scopus 로고    scopus 로고
    • Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: Evidence for intracellular converting enzyme
    • Woods M., Mitchell J.A., Wood E.G., Barker S., Walcot N.R., Rees G.M., et al. Endothelin-1 is induced by cytokines in human vascular smooth muscle cells evidence for intracellular converting enzyme. Mol Pharmacol. 55:1999;902-909
    • (1999) Mol Pharmacol , vol.55 , pp. 902-909
    • Woods, M.1    Mitchell, J.A.2    Wood, E.G.3    Barker, S.4    Walcot, N.R.5    Rees, G.M.6
  • 17
    • 0033735151 scopus 로고    scopus 로고
    • Signal transduction pathways in cytokine stimulation endothelin-1 release from human vascular smooth muscle cells
    • Woods M., Wood E.G., Mitchell J.A., Warner T.D. Signal transduction pathways in cytokine stimulation endothelin-1 release from human vascular smooth muscle cells. J Cardiovasc Pharmacol. 36:2000;S407-S409
    • (2000) J Cardiovasc Pharmacol , vol.36
    • Woods, M.1    Wood, E.G.2    Mitchell, J.A.3    Warner, T.D.4
  • 18
    • 0028121671 scopus 로고
    • Role of cyclic nucleotides in the regulation of endothelin-1 production by human endothelial cells
    • Stewart D.J., Cernacek P., Mohamed F., Blais D., Cianflone K., Monge J.C. Role of cyclic nucleotides in the regulation of endothelin-1 production by human endothelial cells. Am J Physiol. 266:1994;H944-H951
    • (1994) Am J Physiol , vol.266
    • Stewart, D.J.1    Cernacek, P.2    Mohamed, F.3    Blais, D.4    Cianflone, K.5    Monge, J.C.6
  • 19
    • 0029120520 scopus 로고
    • Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression
    • Fujisaki H., Ito H., Hirata Y., Tanaka M., Hata M., Lin M., et al. Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression. J Clin Invest. 96:1995;1059-1065
    • (1995) J Clin Invest , vol.96 , pp. 1059-1065
    • Fujisaki, H.1    Ito, H.2    Hirata, Y.3    Tanaka, M.4    Hata, M.5    Lin, M.6
  • 20
    • 0027984808 scopus 로고
    • Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
    • Rubanyi G.M., Polokoff M.A. Endothelins Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev. 46:1994;325-415
    • (1994) Pharmacol Rev , vol.46 , pp. 325-415
    • Rubanyi, G.M.1    Polokoff, M.A.2
  • 21
    • 0031026210 scopus 로고    scopus 로고
    • Inhibitors of endothelin
    • Webb M.L., Meek T.D. Inhibitors of endothelin. Med Res Rev. 17:1997;17-67
    • (1997) Med Res Rev , vol.17 , pp. 17-67
    • Webb, M.L.1    Meek, T.D.2
  • 22
    • 0025327956 scopus 로고
    • Threshold concentrations of endothelin-1 potentiates contractions to norepinephrine and serotonin in human arteries
    • Yang Z., Richard V., von Segesser L., Bauer E., Stulz P., Turina M., et al. Threshold concentrations of endothelin-1 potentiates contractions to norepinephrine and serotonin in human arteries. Circulation. 82:1990;182-195
    • (1990) Circulation , vol.82 , pp. 182-195
    • Yang, Z.1    Richard, V.2    Von Segesser, L.3    Bauer, E.4    Stulz, P.5    Turina, M.6
  • 23
    • 0001680939 scopus 로고    scopus 로고
    • Evidence of the endothelin-1 autocrine loop in cardiac myocytes: Relation to contractile function with congestive heart failure
    • Thomas P.B., Liu E.C.K., Webb M.L., Mukherjee R., Spinale F.G. Evidence of the endothelin-1 autocrine loop in cardiac myocytes Relation to contractile function with congestive heart failure. Am J Physiol. 40:1996;H2629-H2673
    • (1996) Am J Physiol , vol.40
    • Thomas, P.B.1    Liu, E.C.K.2    Webb, M.L.3    Mukherjee, R.4    Spinale, F.G.5
  • 24
    • 0029087262 scopus 로고
    • Evidence of endothelin-1-mediated vasoconstriction in severe chronic heart failure
    • Kiowski W., Sutsch G., Hunziker P., Muller P., Kim J., Oechslin E., et al. Evidence of endothelin-1-mediated vasoconstriction in severe chronic heart failure. Lancet. 346:1995;732-736
    • (1995) Lancet , vol.346 , pp. 732-736
    • Kiowski, W.1    Sutsch, G.2    Hunziker, P.3    Muller, P.4    Kim, J.5    Oechslin, E.6
  • 25
    • 0032546259 scopus 로고    scopus 로고
    • The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension
    • Krum H., Viskoper R.J., Lacourciere Y., Budde M., Charlon V. The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. N Engl J Med. 338:1998;784-790
    • (1998) N Engl J Med , vol.338 , pp. 784-790
    • Krum, H.1    Viskoper, R.J.2    Lacourciere, Y.3    Budde, M.4    Charlon, V.5
  • 26
    • 0026034713 scopus 로고
    • Increased plasma endothelin-1 in pulmonary hypertension: Marker or mediator of disease?
    • Stewart D.J., Levy R.D., Cernacek P., Langleben D. Increased plasma endothelin-1 in pulmonary hypertension marker or mediator of disease? Ann Intern Med. 114:1991;464-469
    • (1991) Ann Intern Med , vol.114 , pp. 464-469
    • Stewart, D.J.1    Levy, R.D.2    Cernacek, P.3    Langleben, D.4
  • 27
    • 0027943840 scopus 로고
    • Stimulation of interleukin-6 production by endothelin in rat bone marrow-derived stromal cells
    • Agui T., Xin X., Cai Y. Stimulation of interleukin-6 production by endothelin in rat bone marrow-derived stromal cells. Blood. 84:1994;2531-2538
    • (1994) Blood , vol.84 , pp. 2531-2538
    • Agui, T.1    Xin, X.2    Cai, Y.3
  • 28
    • 0032212244 scopus 로고    scopus 로고
    • Endothelin-1 induces production of the neutrophil chemotactic factor interleukin-8 by human brain-derived endothelial cells
    • Hofman F.M., Chen P., Jeyaseelan R. Endothelin-1 induces production of the neutrophil chemotactic factor interleukin-8 by human brain-derived endothelial cells. Blood. 92:1998;3064-3072
    • (1998) Blood , vol.92 , pp. 3064-3072
    • Hofman, F.M.1    Chen, P.2    Jeyaseelan, R.3
  • 29
    • 0032488543 scopus 로고    scopus 로고
    • Angiotensin II and endothelin-1 increase fibroblast growth factor-2 mRNA expression in vascular smooth muscle cells
    • Peifley K.A., Winkles J.A. Angiotensin II and endothelin-1 increase fibroblast growth factor-2 mRNA expression in vascular smooth muscle cells. Biochem Biophys Res Commun. 242:1998;202-208
    • (1998) Biochem Biophys Res Commun , vol.242 , pp. 202-208
    • Peifley, K.A.1    Winkles, J.A.2
  • 30
    • 0000445909 scopus 로고    scopus 로고
    • Endothelin-1 regulation of intercellular adhesion molecule-1 expression in normal and sclerodermal fibroblasts
    • Xu S.-W., Denton C.P., Dashwood M.R., Abraham D.J., Black C.M. Endothelin-1 regulation of intercellular adhesion molecule-1 expression in normal and sclerodermal fibroblasts. J Cardiovasc Pharmacol. 31:(suppl 1):1998;S545-S547
    • (1998) J Cardiovasc Pharmacol , vol.31 , Issue.SUPPL. 1
    • Xu, S.-W.1    Denton, C.P.2    Dashwood, M.R.3    Abraham, D.J.4    Black, C.M.5
  • 31
    • 0025836185 scopus 로고
    • Endothelin, an endothelian dependent vasoconstrictor in sclerderma: Enhanced production and profibrotic action
    • Kahaleh M.B. Endothelin, an endothelian dependent vasoconstrictor in sclerderma Enhanced production and profibrotic action. Arthritis Rheum. 34:1991;978-983
    • (1991) Arthritis Rheum , vol.34 , pp. 978-983
    • Kahaleh, M.B.1
  • 32
    • 0001185590 scopus 로고
    • Endothelin, a potent vasoconstrictor, is a vascular smooth muscle mitogen
    • Dubin D., Pratt R.E., Kooke J.P., Dzau V.J. Endothelin, a potent vasoconstrictor, is a vascular smooth muscle mitogen. J Vas Biol Med. 1:1989;150-154
    • (1989) J Vas Biol Med , vol.1 , pp. 150-154
    • Dubin, D.1    Pratt, R.E.2    Kooke, J.P.3    Dzau, V.J.4
  • 34
    • 0028850818 scopus 로고
    • In vitro effect of endothelin-1 on collagen, and ADP-induced aggregation in human whole blood and platelet rich plasma
    • Knofler R., Urano T., Malyszko J. In vitro effect of endothelin-1 on collagen, and ADP-induced aggregation in human whole blood and platelet rich plasma. Thromb Res. 77:1995;69-78
    • (1995) Thromb Res , vol.77 , pp. 69-78
    • Knofler, R.1    Urano, T.2    Malyszko, J.3
  • 35
    • 0031031440 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Rubin L. Primary pulmonary hypertension. N Engl J Med. 336:1997;111-117
    • (1997) N Engl J Med , vol.336 , pp. 111-117
    • Rubin, L.1
  • 36
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension: Results from a national prospective registry
    • D'Alonzo G.E., Barst R.J., Ayres S.M., Bergofsky E.H., Brundage B.H., Detre K.M., et al. Survival in patients with primary pulmonary hypertension Results from a national prospective registry. Ann Intern Med. 115:1991;343-349
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3    Bergofsky, E.H.4    Brundage, B.H.5    Detre, K.M.6
  • 42
    • 0036163435 scopus 로고    scopus 로고
    • Pulmonary hypertension in systemic lupus erythematosus: Evaluation of clinical characteristics and response to immunosuppressive treatment
    • Tanaka E., Harigai M., Tanaka M., Kawaguchi Y., Hara M., Kamatani N. Pulmonary hypertension in systemic lupus erythematosus Evaluation of clinical characteristics and response to immunosuppressive treatment. J Rheumatol. 29:2002;282-287
    • (2002) J Rheumatol , vol.29 , pp. 282-287
    • Tanaka, E.1    Harigai, M.2    Tanaka, M.3    Kawaguchi, Y.4    Hara, M.5    Kamatani, N.6
  • 43
    • 0343183255 scopus 로고    scopus 로고
    • Primary and secondary pulmonary hypertension in systemic lupus erythematosus
    • Pan T.L., Thumboo J., Boey M.L. Primary and secondary pulmonary hypertension in systemic lupus erythematosus. Lupus. 9:2000;338-342
    • (2000) Lupus , vol.9 , pp. 338-342
    • Pan, T.L.1    Thumboo, J.2    Boey, M.L.3
  • 44
    • 0035797529 scopus 로고    scopus 로고
    • Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred
    • Newman J.H., Wheeler L., Lane K.B., Loyd E., Gaddipati R., Phillips J.A., et al. Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred. N Engl J Med. 345:2001;319-324
    • (2001) N Engl J Med , vol.345 , pp. 319-324
    • Newman, J.H.1    Wheeler, L.2    Lane, K.B.3    Loyd, E.4    Gaddipati, R.5    Phillips, J.A.6
  • 45
    • 0033623296 scopus 로고    scopus 로고
    • Sporadic primary pulmonary hypertension is associated with germ-line mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family
    • Thomson J.R., Machado R.D., Pauciulo M.W., Morgan N.V., Humbert M., Elliott G.C., et al. Sporadic primary pulmonary hypertension is associated with germ-line mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family. J Med Genet. 37:2000;741-745
    • (2000) J Med Genet , vol.37 , pp. 741-745
    • Thomson, J.R.1    MacHado, R.D.2    Pauciulo, M.W.3    Morgan, N.V.4    Humbert, M.5    Elliott, G.C.6
  • 47
    • 0027324745 scopus 로고
    • Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
    • Giaid A., Yanagisawa M., Langleben D., Michel R.P., Levy R., Shennib H., et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med. 328:1993;1732-1739
    • (1993) N Engl J Med , vol.328 , pp. 1732-1739
    • Giaid, A.1    Yanagisawa, M.2    Langleben, D.3    Michel, R.P.4    Levy, R.5    Shennib, H.6
  • 49
    • 0029833777 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in pulmonary hypertension
    • Voelkel N.F., Hoeper M., Maloney J., Tuder R.M. Vascular endothelial growth factor in pulmonary hypertension. Ann N Y Acad Sci. 796:1996;186-193
    • (1996) Ann N Y Acad Sci , vol.796 , pp. 186-193
    • Voelkel, N.F.1    Hoeper, M.2    Maloney, J.3    Tuder, R.M.4
  • 51
    • 0021143486 scopus 로고
    • Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation
    • Yock P., Popp R. Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation. Circulation. 70:1984;657-662
    • (1984) Circulation , vol.70 , pp. 657-662
    • Yock, P.1    Popp, R.2
  • 53
    • 0030955773 scopus 로고    scopus 로고
    • Nitric oxide and prostacyclin as test agents of vasoreactivity in severe precapillary pulmonary hypertension: Predictive ability and consequences on haemodynamics and gas exchange
    • Jolliet P., Bulpa P., Thorens J.B., Ritz M., Chevrolet J.C. Nitric oxide and prostacyclin as test agents of vasoreactivity in severe precapillary pulmonary hypertension Predictive ability and consequences on haemodynamics and gas exchange. Thorax. 52:1997;369-372
    • (1997) Thorax , vol.52 , pp. 369-372
    • Jolliet, P.1    Bulpa, P.2    Thorens, J.B.3    Ritz, M.4    Chevrolet, J.C.5
  • 54
    • 0029985117 scopus 로고    scopus 로고
    • Pulmonary hypertension in systemic sclerosis: An analysis of 17 patients
    • Koh E.R., Lee P., Gladman D.D., Abu-Shakra M. Pulmonary hypertension in systemic sclerosis An analysis of 17 patients. Br J Rheumatol. 35:1996;989-993
    • (1996) Br J Rheumatol , vol.35 , pp. 989-993
    • Koh, E.R.1    Lee, P.2    Gladman, D.D.3    Abu-Shakra, M.4
  • 55
    • 0026632785 scopus 로고
    • The effect of high doses of calcium channel blockers on survival in primary pulmonary hypertension
    • Rich S., Kaufmann E., Levy P.S. The effect of high doses of calcium channel blockers on survival in primary pulmonary hypertension. N Engl J Med. 327:1992;76-81
    • (1992) N Engl J Med , vol.327 , pp. 76-81
    • Rich, S.1    Kaufmann, E.2    Levy, P.S.3
  • 56
    • 0022635636 scopus 로고
    • Pharmacologically induced pulmonary vasodilatation in children and young adults with primary pulmonary hypertension
    • Barst R.J. Pharmacologically induced pulmonary vasodilatation in children and young adults with primary pulmonary hypertension. Chest. 89:1986;497-503
    • (1986) Chest , vol.89 , pp. 497-503
    • Barst, R.J.1
  • 58
    • 0025356811 scopus 로고
    • Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial
    • Rubin L.J., Mendoza J., Hood M., McGoon M., Barst R., Williams W.B., et al. Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial. Ann Intern Med. 112:1990;485-491
    • (1990) Ann Intern Med , vol.112 , pp. 485-491
    • Rubin, L.J.1    Mendoza, J.2    Hood, M.3    McGoon, M.4    Barst, R.5    Williams, W.B.6
  • 59
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
    • Primary Pulmonary Hypertension Study Group, Barst R.J., Rubin L.J., Long W.A., McGoon M.D., Rich S., Badesch D.B., et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med. 334:1996;296-302
    • (1996) N Engl J Med , vol.334 , pp. 296-302
    • Barst, R.J.1    Rubin, L.J.2    Long, W.A.3    McGoon, M.D.4    Rich, S.5    Badesch, D.B.6
  • 60
    • 17144452827 scopus 로고    scopus 로고
    • Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease: A randomized controlled trial
    • Badesch D.B., Tapson V.F., McGoon M.D., Brundage B.H., Rubin L.J., Wigley F.M., et al. Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease a randomized controlled trial. Ann Intern Med. 132:2000;425-434
    • (2000) Ann Intern Med , vol.132 , pp. 425-434
    • Badesch, D.B.1    Tapson, V.F.2    McGoon, M.D.3    Brundage, B.H.4    Rubin, L.J.5    Wigley, F.M.6
  • 61
    • 0034804704 scopus 로고    scopus 로고
    • Medical therapy of pulmonary hypertension: The prostacyclins
    • Galie N., Manes A., Branzi A. Medical therapy of pulmonary hypertension The prostacyclins. Clin Chest Med. 22:2001;529-537
    • (2001) Clin Chest Med , vol.22 , pp. 529-537
    • Galie, N.1    Manes, A.2    Branzi, A.3
  • 62
    • 0037086133 scopus 로고    scopus 로고
    • Treprostinil Study Group. Continuous subcutaneous infusions of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: A double-blind randomized controlled trial
    • Simonneau G., Barst R.J., Galie N., Naeije R., Rich S., Bourge R.C., et al. Treprostinil Study Group. Continuous subcutaneous infusions of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension A double-blind randomized controlled trial. Am J Respir Crit Care Med. 165:2002;800-804
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 800-804
    • Simonneau, G.1    Barst, R.J.2    Galie, N.3    Naeije, R.4    Rich, S.5    Bourge, R.C.6
  • 63
    • 3042686863 scopus 로고    scopus 로고
    • Effect of orally active prostacyclin analogue on survival of outpatients with primary pulmonary hypertension
    • Nagaya N., Uematsu M., Okano Y., Kyotani S., Sakamaki F., Nakanishi F., et al. Effect of orally active prostacyclin analogue on survival of outpatients with primary pulmonary hypertension. J Am Coll Cardiol. 34:1999;1188-1192
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1188-1192
    • Nagaya, N.1    Uematsu, M.2    Okano, Y.3    Kyotani, S.4    Sakamaki, F.5    Nakanishi, F.6
  • 67
    • 0036569119 scopus 로고    scopus 로고
    • Effect of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomized, double-blind, placebo controlled trial
    • Galie N., Humbert M., Vachiery J.L., Vizza C.D., Kneussl M., Manes A., et al. Effect of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension a randomized, double-blind, placebo controlled trial. J Am Coll Card. 39:2002;1496-1502
    • (2002) J Am Coll Card , vol.39 , pp. 1496-1502
    • Galie, N.1    Humbert, M.2    Vachiery, J.L.3    Vizza, C.D.4    Kneussl, M.5    Manes, A.6
  • 68
    • 0034597646 scopus 로고    scopus 로고
    • Sildenafil in primary pulmonary hypertension
    • Prasad S., Wilkinson J., Gatzoulis M.A. Sildenafil in primary pulmonary hypertension. N Engl J Med. 343:2000;1342-1345
    • (2000) N Engl J Med , vol.343 , pp. 1342-1345
    • Prasad, S.1    Wilkinson, J.2    Gatzoulis, M.A.3
  • 69
    • 0035845634 scopus 로고    scopus 로고
    • Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension
    • Wilkens H., Guth A., Koenig J., Forestier N., Cremers B., Hennen B., et al. Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension. Circulation. 104:2001;1218-1222
    • (2001) Circulation , vol.104 , pp. 1218-1222
    • Wilkens, H.1    Guth, A.2    Koenig, J.3    Forestier, N.4    Cremers, B.5    Hennen, B.6
  • 70
  • 71
    • 0035060156 scopus 로고    scopus 로고
    • Short-term oral administration of L-arginine improves hemodynamics and exercise capacity in patients with precapillary pulmonary hypertension
    • Nagaya N., Uematsu M., Oya H., Sato N., Sakamaki F., Kyotani S., et al. Short-term oral administration of L-arginine improves hemodynamics and exercise capacity in patients with precapillary pulmonary hypertension. Am J Respir Crit Care Med. 163:2001;887-891
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 887-891
    • Nagaya, N.1    Uematsu, M.2    Oya, H.3    Sato, N.4    Sakamaki, F.5    Kyotani, S.6
  • 72
    • 0034713874 scopus 로고    scopus 로고
    • Hemodynamic effects of bosentan, an endothelin receptor antagonist, in patients with pulmonary hypertension
    • Williamson D.J., Wallman L.L., Jones R., Keogh A.M., Scroope F., Penny R., et al. Hemodynamic effects of bosentan, an endothelin receptor antagonist, in patients with pulmonary hypertension. Circulation. 102:2000;411-418
    • (2000) Circulation , vol.102 , pp. 411-418
    • Williamson, D.J.1    Wallman, L.L.2    Jones, R.3    Keogh, A.M.4    Scroope, F.5    Penny, R.6
  • 73
    • 0030891727 scopus 로고    scopus 로고
    • Acute and short-term effects of the nonpeptide endothelin-1 receptor antagonist bosentan in humans
    • Sutsch G., Bertel O., Kiowski W. Acute and short-term effects of the nonpeptide endothelin-1 receptor antagonist bosentan in humans. Cardiovasc Drugs Ther. 10:1996;717-725
    • (1996) Cardiovasc Drugs Ther , vol.10 , pp. 717-725
    • Sutsch, G.1    Bertel, O.2    Kiowski, W.3
  • 74
    • 0034903761 scopus 로고    scopus 로고
    • Clinical experience with endothelin receptor antagonists in chronic heart failure
    • Seed A., Love M.P., McMurray J.J. Clinical experience with endothelin receptor antagonists in chronic heart failure. Heart Fail Rev. 6:2001;317-323
    • (2001) Heart Fail Rev , vol.6 , pp. 317-323
    • Seed, A.1    Love, M.P.2    McMurray, J.J.3
  • 75
    • 0035916270 scopus 로고    scopus 로고
    • Hemodynamic effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients with class III and IV congestive heart failure
    • Torre-Amione G., Yong J.B., Durand J., Bozkurt B., Mann D.L., Kobrin I. Hemodynamic effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients with class III and IV congestive heart failure. Circulation. 103:2001;973-980
    • (2001) Circulation , vol.103 , pp. 973-980
    • Torre-Amione, G.1    Yong, J.B.2    Durand, J.3    Bozkurt, B.4    Mann, D.L.5    Kobrin, I.6
  • 76
    • 0034075608 scopus 로고    scopus 로고
    • Acute hemodynamic and neurohumoral effects of selective et (A) receptor blockade in patients with congestive heart failure
    • Spieker L.E., Mitrovic V., Noll G., Pacher R., Schulze M.R., Muntwyler J., et al. Acute hemodynamic and neurohumoral effects of selective ET (A) receptor blockade in patients with congestive heart failure. J Am Coll Cardiol. 35:2000;1745-1752
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1745-1752
    • Spieker, L.E.1    Mitrovic, V.2    Noll, G.3    Pacher, R.4    Schulze, M.R.5    Muntwyler, J.6
  • 77
    • 0029022496 scopus 로고
    • Acute pro-inflammatory actions of endothelin-1 in the guinea-pig lung: Involvement of ET-a and ET-b receptors
    • Filep J.G., Fournier A., Foldes-Filep E. Acute pro-inflammatory actions of endothelin-1 in the guinea-pig lung Involvement of ET-a and ET-b receptors. Br J Pharmacol. 115:1995;227-236
    • (1995) Br J Pharmacol , vol.115 , pp. 227-236
    • Filep, J.G.1    Fournier, A.2    Foldes-Filep, E.3
  • 78
    • 0030755489 scopus 로고    scopus 로고
    • Increased endothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of endothelin receptor antagonist
    • Park S.H., Saleh D., Giaid A., Michel R.P. Increased endothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of endothelin receptor antagonist. Am J Respir Crit Care Med. 156:1997;600-608
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 600-608
    • Park, S.H.1    Saleh, D.2    Giaid, A.3    Michel, R.P.4
  • 79
    • 0029564275 scopus 로고
    • Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats
    • Chen S.J., Chen Y.F., Meng Q.C., Durand J., Dicarlo V.S., Oparil S. Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats. J Appl Physiol. 79:1995;2122-2131
    • (1995) J Appl Physiol , vol.79 , pp. 2122-2131
    • Chen, S.J.1    Chen, Y.F.2    Meng, Q.C.3    Durand, J.4    Dicarlo, V.S.5    Oparil, S.6
  • 80
    • 0035818316 scopus 로고    scopus 로고
    • Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: A randomized placebo-controlled study
    • Channick R.N., Simonneau G., Sitbon O., Robbins I.M., Frost A., Tapson V.F., et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension a randomized placebo-controlled study. Lancet. 358:2001;1119-1123
    • (2001) Lancet , vol.358 , pp. 1119-1123
    • Channick, R.N.1    Simonneau, G.2    Sitbon, O.3    Robbins, I.M.4    Frost, A.5    Tapson, V.F.6
  • 81
    • 0034107636 scopus 로고    scopus 로고
    • Clinical correlates and prognostic significance of 6-minute walk test in patients with primary pulmonary hypertension: Comparison with cardiopulmonary exercise testing
    • Miyamoto S., Nagaya N., Satoh T., Kyotani S., Sakamaki F., Fujita M., et al. Clinical correlates and prognostic significance of 6-minute walk test in patients with primary pulmonary hypertension comparison with cardiopulmonary exercise testing. Am J Respir Crit Care Med. 161:2000;481-492
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 481-492
    • Miyamoto, S.1    Nagaya, N.2    Satoh, T.3    Kyotani, S.4    Sakamaki, F.5    Fujita, M.6
  • 82
    • 0037484589 scopus 로고    scopus 로고
    • Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension. A 1-year follow-up study
    • Sitbon O., Badesch D.B., Channick R.N., Frost A., Robbins I.M., Simonneau G., et al. Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension. A 1-year follow-up study. Chest. 124:2003;247-254
    • (2003) Chest , vol.124 , pp. 247-254
    • Sitbon, O.1    Badesch, D.B.2    Channick, R.N.3    Frost, A.4    Robbins, I.M.5    Simonneau, G.6
  • 84
    • 4043078357 scopus 로고    scopus 로고
    • Effects of the oral endothelial receptor antagonist bosentan in a sub-group of patients with pulmonary artery hypertension related to scleroderma (abstr.)
    • Black C.M. Effects of the oral endothelial receptor antagonist bosentan in a sub-group of patients with pulmonary artery hypertension related to scleroderma (abstr.). Ann Rheum Dis. 61:(suppl 1):2002;109-110
    • (2002) Ann Rheum Dis , vol.61 , Issue.SUPPL. 1 , pp. 109-110
    • Black, C.M.1
  • 85
    • 0344406959 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary artery hypertension
    • Barst R.J., Ivy D., Dingemanse J., Widlitz A., Schmitt K., Doran A., et al. Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary artery hypertension. Clin Pharmacol Ther. 73:2003;372-382
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 372-382
    • Barst, R.J.1    Ivy, D.2    Dingemanse, J.3    Widlitz, A.4    Schmitt, K.5    Doran, A.6
  • 86
    • 0037465729 scopus 로고    scopus 로고
    • Influence of inhaled iloprost on transpulmonary gradient of big endothelin in patients with pulmonary hypertension
    • Wilkens H., Bauer M., Forestier N., Konig J., Eichler A., Schneider S., et al. Influence of inhaled iloprost on transpulmonary gradient of big endothelin in patients with pulmonary hypertension. Circulation. 107:2003;1509-1517
    • (2003) Circulation , vol.107 , pp. 1509-1517
    • Wilkens, H.1    Bauer, M.2    Forestier, N.3    Konig, J.4    Eichler, A.5    Schneider, S.6
  • 87
    • 0041742185 scopus 로고    scopus 로고
    • Bosentan treatment in patients with primary pulmonary hypertension receiving nonparenteral prostanoids
    • Hoeper M.M., Taha N., Bekjarova A., Gatzke R., Spiekerkoetter E. Bosentan treatment in patients with primary pulmonary hypertension receiving nonparenteral prostanoids. Eur Respir J. 22:2003;330-334
    • (2003) Eur Respir J , vol.22 , pp. 330-334
    • Hoeper, M.M.1    Taha, N.2    Bekjarova, A.3    Gatzke, R.4    Spiekerkoetter, E.5
  • 88
    • 0038441800 scopus 로고    scopus 로고
    • Bosentan for the treatment of pulmonary arterial hypertension
    • Kanyon K.W., Nappi J.M. Bosentan for the treatment of pulmonary arterial hypertension. Ann Pharmacother. 37:2003;1055-1062
    • (2003) Ann Pharmacother , vol.37 , pp. 1055-1062
    • Kanyon, K.W.1    Nappi, J.M.2
  • 89
    • 0033758617 scopus 로고    scopus 로고
    • Attenuation of pulmonary vascular hypertension and cardiac hyperthrophy with sitaxsentan sodium, an orally active et (A) receptor antagonist
    • Tilton R.G., Munsch C.L., Sherwood S.J., Chen S.J., Chen Y.F., Wu C., et al. Attenuation of pulmonary vascular hypertension and cardiac hyperthrophy with sitaxsentan sodium, an orally active ET (A) receptor antagonist. Pulmonary Pharmacol Ther. 13:2000;87-97
    • (2000) Pulmonary Pharmacol Ther , vol.13 , pp. 87-97
    • Tilton, R.G.1    Munsch, C.L.2    Sherwood, S.J.3    Chen, S.J.4    Chen, Y.F.5    Wu, C.6
  • 90
    • 0036283401 scopus 로고    scopus 로고
    • Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension
    • Barst R.J., Rich S., Widlitz A., Horn E.M., McLaughlin V., McFarlin J. Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension. Chest. 121:2002;1860-1868
    • (2002) Chest , vol.121 , pp. 1860-1868
    • Barst, R.J.1    Rich, S.2    Widlitz, A.3    Horn, E.M.4    McLaughlin, V.5    McFarlin, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.