Evidence for the presence of glucose transporter 4 in the endometrium and its regulation in polycystic ovary syndrome patients

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 8, 2004, Pages 4089-4096

  Mioni, Roberto ^a   Chiarelli, Silvia ^a   Xamin, Nadia ^a   Zuliani, Laura ^a   Granzotto, Marnie ^a   Mozzanega, Bruno ^a   Maffei, Pietro ^a   Martini, Chiara ^a   Blandamura, Stella ^a   Sicolo, Nicola ^a   Vettor, Roberto ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 4; MESSENGER RNA;

ADULT; ARTICLE; BODY WEIGHT; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOMETRIUM; FEMALE; GLUCOSE METABOLISM; HORMONE METABOLISM; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; IMMUNOHISTOCHEMISTRY; INSULIN SENSITIVITY; INSULINEMIA; LEAN BODY WEIGHT; MENSTRUAL CYCLE; OBESITY; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

ADULT; ENDOMETRIUM; FEMALE; GLUCOSE TRANSPORTER TYPE 4; HUMANS; HYPERINSULINISM; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; MENSTRUAL CYCLE; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; OBESITY; POLYCYSTIC OVARY SYNDROME; RNA, MESSENGER; STAINING AND LABELING; THINNESS;

FALLOPIA;

EID: 4043100650     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-032028     Document Type: Article

References (43)

1. Hull MGR 1987 Epidemiology of infertility and polycystic ovarian disease: endocrinological and demographic studies. Gynecol Endocrinol 1:235-245
2. Solomon CG 1999 The epidemiology of polycystic ovary syndrome. Prevalence and associated disease risks. Endocrinol Metab Clin North Am 28:247-263
3. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R 1998 Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 83:3078-3082
4. Burghen GA, Givens JR, Kitabchi AE 1980 Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease. J Clin Endocrinol Metab 50:113-116
5. Franks S 1995 Polycystic ovary syndrome. N Engl J Med 333:853-861
6. Dunaif A, Graf M, Mandali J, Laumans V, Dobrjansky A 1987 Characterisation of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance and/or hyperinsulinemia. J Clin Endocrinol Metab 65:499-508
7. Franks S 1989 Polycystic ovary syndrome: changing perspective. Clin Endocrinol (Oxf) 31:87-120
8. Ciaraldi T, El Roeiy A, Madar D, Reichart D, Olefs KY, Yen S 1992 Cellular mechanisms of insulin resistance in polycystic ovarian syndrome. J Clin Endocrinol Metab 75:577-583
9. Poretsky L 1994 Insulin resistance and hyperandrogenism. Endocr Rev 2:125-129
10. Toprak S, Yonem A, Cakir B, Guler S, Azal O, Ozata M, Corakci A 2001 Insulin resistance in nonobese patiente with polycystic ovary syndrome. Horm Res 55:65-70
11. Nestler JE, Jakubowicz DJ, Evans WS, Fasquali R 1998 Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome. N Engl J Med 338:1876-1880
12. Hasegawa I, Murukawa H, Suzuki M, Yamamoto Y, Kurabayashi T, Tamaka K 1999 Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome. Fertil Steril 69:691-696
13. Kocak M, Caliskan E, Simsir C, Haberal A 2002 Metformin therapy improves ovulatory rates, cervical scores and pregnancy rates in clomiphene citrate-resistant with polycystic ovary syndrome. Fertil Steril 77:101-106
14. Moran LJ, Noakes M, Clifton PM, Tomlinson L, Norman RJ 2003 Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome. J Clin Endocrinol Metab 88:812-819
15. Hackl H 1973 Metabolism of glucose in the human endometrium with special reference to fertility and contraception. Acta Obstet Gynecol Scand 52:135-140
16. Truchan B, Taylor P, Goren HJ, Lederis K, Hollenberg MD, Okabe T 1987 Basal, oxytocin- and insulin-stimulated glucose oxidation in human endometrium. Can J Physiol Pharmacol 65:323-327
17. Straus DS 1984 Growth-stimulatory actions of insulin in vitro and in vivo. Endocr Rev 5:356-369
18. Strowitzki T, Corleta Von Eye H, Kellerer M, Häring HU 1993 Tyrosine kinase activity of insulin like growth factors I and insulin receptors in human endometrium during the menstrual cycle: cyclic variation of insulin receptor expression. Fertil Steril 59:315-322
19. Korgun ET, Denir R, Hammer A, Dohr G, Desoye G, Skofitch G, Hahn T 2001 Glucose transporter expression in rat embryo and uterus during decidualization, implantation, and early postimplantation. Biol Reprod 65:1364-1370
20. Strowitzki T, Capp E, von Wolff M, Mùller-Höcker J 2001 Expression of glucose transporter 1 in human endometrial and decidual tissue. Gynecol Endocrinol 15:219-224
21. Rosenbaum D, Haber RS, Dunaif A 1993 Insulin resistance in polycystic ovary syndrome: decreased expression of GLUT-4 glucose transporters in adipocytes. Am J Physiol 264:E197-E202
22. Matsuda M, DeFronzo RA 1999 Insulin sensitivity indices obtained from oral glucose tolerance testing. Comparison with the euglycemic insulin clamp. Diabetes Care 22:1462-1470
23. 1997 Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 20:1183-1197
24. Onnis A, Nardelli GB, Mozzanega B, Lamina V, Onnis GL, Maggino T, Litta P, Marchetti M 1984 Progestinic treatment of mastodynia. Eur J Gynaecol Oncol 1:11-15
25. Sheet EE, Tsibris JC, Cook NI, Virgin SD, De May RM, Spellacy WN 1985 in vitro binding of insulin and epidermal growth factor to human endometrium and endocervix. Am J Obstet Gynecol 153:60-65
26. Jansson T, Wennergren M, Illsley NP 1993 Glucose transporter expression and distribution in the human placenta throughout gestation and in intrauterine growth retardation. J Clin Endocrinol Metab 77:1554-1562
27. Barros LF, Yudilevich DL, Jarvis SM, Beaumont N, Baldwin SA 1995 Quantitation and immunolocalisation of glucose transporters in the human placenta. Placenta 16:623-633
28. Zorzano A, Wilkinson W, Kotliar N, Thoidis G, Wadzinkski BE, Ruoho AE, Pilch PF, Wilkinson W, Kotliar N 1989 Insulin regulated glucose-uptake in rat adipocytes is mediated by 2 transporter isoforms present in at least two vesicle populations. J Biol Chem 264:12358-12363
29. Marette A, Richardson JM, Ramlal T, Balon TW, Vranic M, Pessin JE, Klip A 1992 Abundance, localisation and insulin-induced translocation of glucose transporters in red and white muscle. Am J Physiol 263:C443-C452
30. Pilch PF, Wilkinson W, Garvey WT, Ciaraldi TP, Hueckstaedt TP, Olefsky JM 1993 Insulin responsive human adipocytes express two glucose transporter isoforms and target them to different vesicles. J Clin Endocrinol Metab 77: 286-289
31. Zorzano A, Munoz P, Camps M, Mora C, Testar X, Palacin M 1996 Insulin-induced redistribution of GLUT4 glucose carriers in the muscle fiber. In search of GLUT4 trafficking pathways. Diabetes 45:S70-S81
32. Pessin JE, Thurmond DC, Elmendorf JS, Coker KJ, Okada S 1999 Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. J Biol Chem 274:2593-2596
33. Gurpide E, Tabanelli S, Tang B 1992 Human endometrial stromal cells. In: Genazzani A, Petraglia F, eds. Hormones in gynecological endocrinology. Canforth, Lancs, UK: Parthenon Publishing; 717-724
34. Roy SK, Greenwald GS 1991 In vitro effects of epidermal growth factor, insulin-like growth factor-I, fibroblast growth factor, and follicle-stimulating hormone on hamster follicular deoxyribonucleic acid synthesis and steroidogenesis. Biol Reprod 44:889-896
35. Roberts AJ, Skinner MK 1991 Transforming growth factor-α and -β differentially regulate growth and steroidogenesis of bovine thecal cells during antral follicle development. Endocrinology 129:2041-2048
36. Ferrara N, Houck K, Jakeman L, Leung DW 1992 Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr Rev 13:18-32
37. Dunaif A 1997 Insulin resistance and the polycystic ovary syndrome: mechanism and implication for pathogenesis. Endocr Rev 18:774-800
38. Garvey WT, Maianu L, Hancock JA, Golkhowski AM, Baron A 1992 Gene expression of GLUT4 in skeletal muscle from insulin-resistant patients with obesity, IGT, GDM, and NIDDM. Diabetes 41:465-475
39. Shepherd PR, Kahn BB 1999 Glucose transporters and insulin action-implication for insulin resistance and diabetes mellitus. N Engl J Med 341: 248-257
40. Mueckler M 2001 Insulin resistance and the disruption of GLUT4 trafficking in skeletal muscle. J Clin Invest 107:1211-1213
41. Rosenbaum D, Haber RS, Dunaif A 1993 Insulin resistance in polycystic ovary syndrome: decreased expression of GLUT-4 glucose transporters in adipocytes. Am J Physiol 264:E197-E202
42. Rosenfield RL 2001 Polycystic ovary syndrome and insulin-resistant hyperinsulinemia. J Am Acad Dermatol 45:S95-S102
43. Dunaif A, Segal KR, Futterweit W, Dobrjansky A 1989 Profound peripheral insulin resistance, independent of obesity, in the polycystic ovary syndrome. Diabetes 38:1165-1174