Development and validation of an LC/MS/MS procedure for the quantification of endogenous myo-inositol concentrations in rat brain tissue homogenates

Analytical Chemistry

Volumn 76, Issue 16, 2004, Pages 4901-4908

  Kindt, Erick ^a   Shum, Yin ^a   Badura, Lori ^b   Snyder, Peter J ^b   Brant, Ashley ^a   Fountain, Scott ^a   Szekely Klepser, Gabriella ^a  

^a PFIZER INC   (United States)

^b MS 8220 1002 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; CALIBRATION; DRUG PRODUCTS PLANTS; MASS SPECTROMETRY; TISSUE;

MYO-INOSITOL METABOLISM; QUANTITATIVE MEASURES;

DISEASE CONTROL;

BIOLOGICAL MARKER; INOSITOL;

ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CALIBRATION; CHIRALITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PROTEIN CONTENT; PROTEIN METABOLISM; QUANTITATIVE ANALYSIS; RAT; TISSUE HOMOGENATE; VALIDATION PROCESS;

ANIMALS; BRAIN CHEMISTRY; CALIBRATION; CHROMATOGRAPHY, LIQUID; INOSITOL; MASS SPECTROMETRY; RATS; STEREOISOMERISM;

EID: 4043098891     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac049746w     Document Type: Article

References (30)

1. Wang, W.; Safar, J.; Zopf, D. Anal. Biochem. 1990, 188, 432-435.
2. Holub, B. J. Adv. Nutr. Res. 1982, 4, 107-141.
3. Downes, C.; Macphee, C. Eur. J. Biochem. 1990, 193, 1-18.
4. Kreis, R.; Ernst, T.; Ross, B. D. Magn. Reson. Med. 1993, 30, 424-437.
5. Berridge, M. J.; Downes, C. P.; Hanley, M. R. Biochem. J. 1982, 206, 587-595.
6. Palatnik, A.; Frolov, K.; Fux, M.; Benjamin, J. J. Clin. Psychopharmacol. 2001, 21, 335-339.
7. Cohen, M. P. The Polyol Paradigm and Complications of Diabetes; Springer-Verlag: New York, 1987; Chapter 4.
8. Greene, D. A.; Jesus, P. V. D., Jr.; Winegrad, A. I. J. Clin. Invest. 1975, 55, 1326-1336.
9. Shetty, H. U.; Schapiro, M. B.; Holloway, H. W.; Rapoport, S. I. J. Clin. Invest. 1995, 95, 542-546.
10. Huang, W.; Alexander, G. E.; Daly, E. M.; Shetty, H. U.; Krasuski, J. S.; Rapoport, S. I.; Schapiro, M. B. Am. J. Psychiatry 1999, 156, 1879-1886.
11. Doraiswamy, P.; Cjares, H.; Krishnan, K. Lancet 1998, 352, 1678.
12. Klunk, W.; Xu, C.; Panchalingam, K.; McClure, J.; Pettegrew, J. W. Neurobiol. Aging 1996, 17, 349-357.
13. Heilig, C.; Stromski, M.; Blumenfeld, J.; Lee, J.; Gullans, S. Am. J. Physiol. 1998, 257, F1108-1116.
14. Clements, R.; DeJesus, P.; Winegard, A. Lancet 1973, (26 May), 1137-1141.
15. Meyerhoff, D.; MacKay, S.; Constans, J.; Norman, D., Van Dyke, C.; Fein, G.I; Weiner, M. Ann. Neurol. 1994, 36, 40-47.
16. Brook, W.; Stidley, C.; Petropoulos, H.; Jung, R.; Weers, D.; Friedman, S.; Barlow, M.; Sibbitt, W.; Yeo, R. J. Neurotrauma 2000, 17, 629-640.
17. Constans, J. M.; Meyerhoff, D. J.; Gerson, J.; MacKay, S.; Norman, D.; Fein, G.; Weiner, M. W. Radiology 1995, 197, 517-523.
18. Klunk, W. E.; Panchalingam, K.; Moossy, J.; McClure, R. J.; Pettegrew, J. W. Neurology 1992, 42, 1578-1585.
19. Catani, M.; Cherubini, A.; Howard, R.; Tarducci, R.; Pelliecioli, M.; Gobbi, G.; Senin, U.; Mecocci, P. NeuroReport 2001, 12, 2315-2317.
20. Kusmierz, J.; DeGeorge, J. J.; Sweeney, D.; May, C.; Rapoport, S. I. J. Chromatogr. 1989, 497, 39-48.
21. Shetty, H.; Huang, W. Curr. Org. Chem. 2000, 4, 1-17.
22. Hasegawa, M.; Doi, K.; Baba, S. Clin. Chim. Acta 1988, 176, 207-212.
23. Shetty, H. U.; Holloway, H. W.; Rapoport, S. I. Anal. Biochem. 1995, 224, 279-285.
24. Dittmer, J.; Douglas, M. Ann. N. Y. Acad. Sci. 1969, 165, 515-525.
25. Yamada, M.; Kakita, A.; Mizuguchi, M.; Rhee, S. G.; Kim, S. U.; Ikuta, F. Developmental. Brain Research. 1993, 71, 137-145.
26. Klampfl, C.; Buchberger, W. Eletrophoresis 2001, 22, 2737-2742.
27. Yao, F. S.; Caserta, M. T.; Wyrwicz, A. M. Int. J. Devl. Neurosci. 2000, 18, 822-841.
28. Eichberg, J.; Hauser, G. Biochim. Biophys. Acta 1973, 326, 210-223.
29. US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), and Center for Veterinary Medicine (CVM) Guidance for Industry Bioanalytical Method Validation; May 2001.
30. Li, W.; Cohen, L. Anal. Chem. 2003, 75, 5854-5859.