Polyarteritis nodosa associated with hepatitis B virus infection. The role of antiviral treatment and mutations in the hepatitis B virus genome

European Journal of Gastroenterology and Hepatology

Volumn 16, Issue 8, 2004, Pages 801-807

  Janssen, Harry L A ^a   Van Zonneveld, Monika ^a   Van Nunen, Andeltje B ^a   Niesters, Hubert G M ^b   Schalm, Solko W ^a   De Man, Robert A ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Hepatitis B; Interferon; Lamivudine; Polyarteritis nodosa; Viral mutants

Indexed keywords

ALPHA INTERFERON; ANTIVIRUS AGENT; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; PREDNISONE; VIRUS DNA;

ADULT; ANOREXIA; ARTICLE; CASE REPORT; CLINICAL FEATURE; COMBINATION CHEMOTHERAPY; DISEASE ASSOCIATION; DISEASE COURSE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN TISSUE; LABORATORY TEST; LIVER BIOPSY; MALE; MONOTHERAPY; MUSCLE BIOPSY; NONHUMAN; POLYARTERITIS NODOSA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REMISSION; SEROCONVERSION; SIDE EFFECT; STOP CODON; TREATMENT OUTCOME; VIRUS GENOME; VIRUS LOAD; VIRUS MUTATION; WEIGHT REDUCTION;

ADULT; AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; COMBINED MODALITY THERAPY; GENOME, VIRAL; HEPATITIS B; HEPATITIS B VIRUS; HUMANS; INTERFERON TYPE II; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; POLYARTERITIS NODOSA; PREDNISONE; SEQUENCE ALIGNMENT;

EID: 4043094986     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.meg.0000108362.41221.57     Document Type: Article

References (22)

1. McMahon BJ, Heyward WL, Templin DW, Clement D, Lanier AP. Hepatitis B-associated polyarteritis nodosa in Alaskan Eskimos: clinical and epidemiologic features and long-term follow-up. Hepatology 1989; 9:97-101.
2. Guilllevin L, Lhote F, Cohen P, Sauvaget F, Jarrousse B, Lortholary O, et al. Polyarteritis nodosa related to hepatitis B virus. A prospective study with long-term observation in 41 patients. Medicine 1995; 74:238-253.
3. Lightfoot RW Jr, Michel BA, Bloch DA, Hunder GG, Zvaifler NJ, McShane DJ, et al. The American College of Rheumatology, 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum 1990; 33: 1088-1093.
4. Leib ES, Restivo C, Paulus HE. Immunosuppressive and corticosteroid therapy of polyarteritis nodosa. Am J Med 1979; 67:941-947.
5. Trepo C, Zuckerman AJ, Bird RC, Prince AM. The role of circulating hepatitis B antigen/antibody immune complexes in the pathogenesis of vascular and hepatic manifestations in polyarteritis nodosa. J Clin Pathol 1974; 27:863-886.
6. Wardelle-Bladou C, Lafon J, Trepo C, Pichoud C, Picon M, Pellissier J, Zoulim F. Successful combination therapy of polyarteritis nodosa associated with a pre-core promoter mutant hepatitis B virus infection. J Hepatol 2001; 34:774-779.
7. Niesters HGM, Honkoop P, Haagsma EB, de Man RA, Schalm SW, Osterhaus ADME. Identification of more than one mutation in the hepatitis B virus polymerase gene arising during prolonged lamivudine treatment. J Infect Dis 1998; 177:1382-1385.
8. Stuyver L, De Gendt S, Van Geyt C, Zoulim F, Fried M, Schinazi RF, Rossau R. A new genotype of hepatitis B: complete genome and phylogenetic relatedness. J Gen Virol 2000; 81:67-74.
9. Guillevin L, Lhote F, Jarrousse B, Bironne P, Barrier J, Deny P, Trepo C. Polyarteritis nodosa related to hepatitis B virus. A retrospective study of 66 patients. Ann Med Interne 1992; 143 (suppl 1):63-74.
10. Guilllevin L, Lhote F, Leon A, Fauvelle F, Vivitski L, Trepo C. Treatment of polyarteritis nodosa related to hepatitis B virus with short term steroid therapy associated with antiviral agents and plasma exchanges. A prospective trial in 33 patients. J Rheumatol 1993; 20:289-298.
11. Guilllevin L, Lhote F, Sauvaget F, Deblois P, Rossi F, Levallois D, et al. Treatment of polyarteritis nodosa related to hepatitis B virus with interferon-alpha and plasma exchanges. Ann Rheum Dis 1994; 53: 334-337.
12. Avsar E, Savas B, Tözün N, Ulusoy NB, Kalayci C. Successful treatment of polyarteritis nodosa related to hepatitis B virus with interferon alpha as first line therapy. J Hepatol 1998; 28:525-526.
13. Krüger M, Böker KHW, Zeidler H, Manns MP. Treatment of hepatitis B-related polyarteritis nodosa with famciclovir and interferon alfa-2b. J Hepatol 1997; 26:935-939.
14. Miguelez M, Bueno J, Laynez P. Polyarteritis nodosa associated with precore mutant hepatitis B virus infection. Ann Rheum Dis 1998; 57:173.
15. Bedani PL, Sagir A, Guillevin L, Neuen-Jacob E, Häussinger D. Successful treatment of hepatitis B virus associated polyarteritis nodosa with a combination of prednisolone, α-interferon and lamivudine. J Hepatol 2000; 33:677-683.
16. Trepo C, Guillevin L. Polyarteritis nodosa and extrahepatic manifestations of HBV infection: the case against autoimmune intervention in pathogenesis. J Autoimmun 2001; 16:269-274.
17. Maclachlan D, Battegay M, Jacob AL, Tyndall A. Successful treatment of hepatitis B-associated polyarteritis nodosa with a combination of lamivudine and conventional immunosuppressive therapy: a case report. Rheumatology 2000; 39:106-108.
18. Nunen van AB, Hansen BE, Suh DJ, Lohr HF, Chemello L, Fontaine H, et al. Durability of HBeAg seroconversion following antiviral therapy for chronic hepatitis B. Gut 2003 52:420-424.
19. Schalm SW, Heathcote J, Cianciara J, Farrell G, Sherman M, Willems B, et al. Lamivudine and alpha-interferon treatment of patients with chronic hepatitis B infection: a randomized controlled trial. Gut 2000; 46: 562-568.
20. Wicki J, Olivieri J, Pizzolato G, Sarasin F, Guillevin L, Dayer J-M, Chizzolini C. Successful treatment of polyarteritis nodosa related to hepatitis B virus with a combination of lamivudine and interferon-alpha. Rheumatology 1999; 38:183-185.
21. Erhardt A, Sagir A, Guillevin L, Neuen-Jacob E, Häussinger D. Successful treatment of hepatitis B virus associated polyarteritis nodosa with a combination of prednisolone, α-interferon and lamivudine. J Hepatol 2000; 33:677-683.
22. 2b therapy: successful treatment with a combination of interferon, lamivudine, plasma exchanges and steroids. Clin Rheumatol 2001; 20:290-292.