A negative personal and family history for venous thrombotic events is not sufficient to exclude thrombophilia in patients with cerebral venous thrombosis

European Journal of Neurology

Volumn 11, Issue 8, 2004, Pages 555-558

  Amberger, N ^a   Masuhr, F ^a   Valdueza, J M ^a   Vetter, B ^a   Weih, M ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cerebral venous thrombosis; Thrombophilia; Thrombotic history

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN;

ADULT; ANAMNESIS; ARTICLE; BRAIN VEIN; CONTROLLED STUDY; DIAGNOSTIC VALUE; FAMILY HISTORY; FEMALE; GENETIC DISORDER; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; THROMBOPHILIA; VEIN THROMBOSIS;

ADULT; CASE-CONTROL STUDIES; FACTOR V; FAMILY HEALTH; FEMALE; GENETIC PRIVACY; HUMANS; INTRACRANIAL THROMBOSIS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; QUESTIONNAIRES; THROMBOPHILIA; VENOUS THROMBOSIS;

EID: 4043087701     PISSN: 13515101     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2004.00862.x     Document Type: Article

References (18)

1. Ameri A, Bousser MG (1992). Cerebral venous thrombosis. Neurol Clin 10:87-111.
2. Bertina RM, Koeleman BP, Koster T et al. (1994). Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369:64-67.
3. de Bruijn SF, Stam J, Koopman MM, Vandenbroucke JP (1998). Case-control study of risk of cerebral sinus thrombosis in oral contraceptive users and in [correction of who are] carriers of hereditary prothrombotic conditions. The Cerebral Venous Sinus Thrombosis Study Group. BMJ 316:589-592.
4. De Stefano V, Finazzi G, Mannucci PM (1996). Inherited thrombophilia: pathogenesis, clinical syndromes, and management. Blood 87:3531-3544.
5. Frezzato M, Tosetto A, Rodeghiero F (1996). Validated questionnaire for the identification of previous personal or familial venous thromboembolism. Am J Epidemiol 143:1257-1265.
6. Koster T, Rosendaal FR, Briet E et al. (1995). Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study). Blood 85:2756-2761.
7. Martinelli I, Sacchi E, Landi G, Zaioli E, Duca F, Mannucci PM (1998a). High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives. N Engl J Med 338:1793-1797.
8. Martinelli I, Mannucci PM, De Stefano V et al. (1998b). Different risks of thrombosis in four coagulation defects associated with inherited thrombophilia: a study of 150 families. Blood 92:1353-2358.
9. Middeldorp S, Meinardi JR, Koopman MM et al. (2001). A prospective study of asymptomatic carriers of the factor V Leiden mutation to determine the incidence of venous thromboembolism. Ann Intern Med 135:322-327.
10. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM (1996). A common genetic variation in the 3-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88:3698-3703.
11. Reuner KH, Ruf A, Grau A et al. (1998). Prothrombin gene G20210 → A transition is a risk factor for cerebral venous thrombosis. Stroke 29:1765-1769.
12. Ridker PM, Hennekens CH, Lindpaintner K, Stampfer MJ, Eisenberg PR, Miletich JP (1995). Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N Engl J Med 332:912-917.
13. Salomon O, Steinberg DM, Zivelin A et al. (1999). Single and combined prothrombotic factors in patients with idiopathic venous thromboembolism: prevalence and risk assessment. Arterioscler Thromb Vasc Biol 3:511-518.
14. Seligsohn U, Lubetsky A (2001). Genetic susceptibility to venous thrombosis. N Engl J Med 344:1222-1231.
15. Svensson PJ, Dahlback B (1994). Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 330:517-522.
16. Thomas R (2001). Hypercoagulability syndromes. Arch Intern Med 161:2433-2439.
17. Weih M, Junge-Hülsing J, Mehraein S, Ziemer S, Einhäupl KM (2000a). Hereditary thrombophilia with ischemic stroke and sinus thrombosis. Diagnosis, therapy and meta-analysis. Nervenarzt 71:936-945.
18. Weih M, Vetter B, Castell S, Ziemer S, Kulozik AE, Einhaupl KM (2000b). Hereditary thrombophilia in cerebral venous thrombosis. Cerebrovasc Dis 10:161-162.