Role of flavonoids in the prevention of haematotoxicity due to chemotherapeutic agents

HAEMA

Volumn 7, Issue 3, 2004, Pages 313-320

  Lahouel, Mesbah ^a,c   Fillastre, Jean Paul ^b  

^a UNIVERSITY OF JIJEL   (Algeria)

^b Dept de Médecine Interne Ctr Hosp Univ Rouen Boisguillaume   (France)

^c FACULTÉ DE MÉDECINE   (France)

Author keywords

Chemotherapeutic agents; Flavonoids; Protection; Rat; Toxicity

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DAFLON; DAUNORUBICIN; DIOSMIN; DOXORUBICIN; FLAVONOID; HESPERIDIN; POLYPHENOL; PROPOLIS; QUERCETIN;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD TOXICITY; CONTROLLED STUDY; FEMALE; LEUKOPENIA; NONHUMAN; PROTECTION; RAT;

EID: 4043084808     PISSN: 11082682     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Follezou JY, Pouillart P. Chimiothιrapie anticancéreuse. Edition Doin, Paris, 1980, p. 202.
2. Lahouel M. Etude de la toxicité hématologique et rénale de deux médicaments anticancéreux; la Doxorubicine et le CCNU chez le rat. Thèse Doctorat de toxicologie, Rouen (France), 1985.
3. Lahouel M, Viotte G, Sumereau E et al. Haematotoxicity of Doxorubicin and CCNU and of their association in rats. Drugs Exptl Clin Res 1987; 10: 593-599.
4. Raguenez-Viotte G, Lahouel M, Ducastelle T et al. CCNU-Adriamycin association induces earlier and more server nephropathy in rats. Arch Toxicol 1988; 61: 282-291.
5. Fillastre JP, Morin JP, Godin M, Josse S. Complications rénales de la chimiothérapie anticancéreuse. Path Biol 1986; 34: 1013-1028.
6. Viotte G, Lahouel M, Hemet J et al. Hépatopathie d'évolution progressive vers une cirrhose biliaire primitive après administration du CCNU chez le rat. Path Biol 1987; 35: 139-144.
7. Guengerich EP. Mammalian cytochromes P 450. CRC press, Florida, 1986.
8. Omura T, Fuju K. Cytochromes P 450. Edition Kuriya May, Tokyo, 1993, p. 202.
9. Boiron M. treatment of virus associated tumors with interferon. Path Biol 1986; 34: 1041-1045.
10. er séminaire national sur les substances bio-actives d'origine végétale, Jijel, 7 et 8 mai 2001.
11. Sadzuka Y, Sugiyama T, Shimoi K et al. Protective effect of flavonoids on doxorubicin-induced cardiotoxiciy. Toxicol Lett 1997; 92: 1-7.
12. Harborne JB, Williams CA. Advances in flavonoid research since 1992. Phytochemestry 2000; 55: 481-504.
13. Lopez-Lazaro M, Martin-Cordero C, Ayuso MJ. Two new flavonol glycosides as DNA topoisomerase I poisons. Z Naturforsch 2000; 55: 898-902.
14. Siess MH, Le Bon AM, Canivenc-Lavier MC, Saschetet M. Mechanisms involved in the chemoprevention of flavonoids. Biofactors 2000; 12: 193-199.
15. Markham KR. Techniques of flavonoid identification. Academic press. London, 1982, pp. 260-285.
16. Chang P, Riggs CE Jr, Scheerer MT et al. Combination chemotherapy with adriamycin and streptozotocin. II. Clinicopharmacology correlation of augmented adriamycin toxicity caused by streptozotocin. Clin Pharm Ther 1976; 20: 611-616.
17. Kawabata TT, Chapman MY, Kim DH et al. Mechanisms of in vitro immunosuppression by hepatocyte-generated cyclophosphamide metabolites and 4-hydroxycyclophosphamide. Biochem Pharmacol 1990; 40: 927-935.
18. Morin D, Barthelemy S, Zini R et al. Curcumin induces the mitochondrial permeability transition pore mediated by membrane protein thiol oxidation. Febs Letters 2001; 495: 131-136.
19. Torel J, Cillard J, Cillard P. Antioxidant activity of flavonoids and reactivity with peroxy radical. Phytochem 1986; 25: 383-385.
20. Remesy C, Morand C, Demigne O et al. Interet nutritional des flavonoids. Med Nutr 1996, 32: 17-27.
21. Koreichi L. Etude du rτle antioxydant des flavonoides extraits des plantes au cours des réactions immunologiques. Thèse de doct.d'état en biologie moléculaire. Universitë Mentouri, Constantine (Algérie), 2003, pp. 1-186.
22. Le Pecq JB. Mécanisme d'action des substances antitumorales. Edition Herman, Paris, 1978, pp. 90-115.
23. Kamei H, Koide T, Kojimam T et al. Flavonoid-mediated tumor growth suppression demonstrated by in vivo study. Cancer Biother Radiopharm 1996; 11: 193-196.
24. Burdock GA. Review of the biological properties and toxicity of bee propolis (propolis). Food Chem Toxicol 1998; 36: 347-363.