The relationship between the analgesic and hypnotic effects of volatile anesthetic and GABAA receptor

Chinese Pharmacological Bulletin

Volumn 20, Issue 5, 2004, Pages 521-523

  Yan, Mei ^a   Dai, Ti Jun ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Analgesics; Bicuculline; GABA A receptor; Hypnotics; Securinine; Volatile anesthetic

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ANALGESIC AGENT; BICUCULLINE; ENFLURANE; HYPNOTIC AGENT; INHALATION ANESTHETIC AGENT; ISOFLURANE; SECURININE; SEVOFLURANE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG TARGETING; FEMALE; HOT PLATE TEST; HYPNOSIS; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PAIN THRESHOLD; SLEEP TIME; WRITHING TEST;

EID: 4043056508     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Frank NP,Lieb WR. Molecular and cellular mechanisms of general anesthesia. Nature, 1994;367(17):607-14
2. Hall AC, Lieb WR, Franks NP. Stereoselective and non-stereoselective actions of isoflurane on the GABAA receptor. Br J Pharmacol, 1994;112(3):906-10
3. A-mediated inhibition of Purkinje cells in rat cerebellar slices. J Neurophysiol, 1997;77(5):2525-38