Successful rechallenge with slowly titrated lamotrigine after rash

Bipolar Disorders

Volumn 6, Issue 4, 2004, Pages 338-339

  Manfredi, Giovanni ^a   Pacchiarotti, Isabella ^b   Kotzalidis, Giorgio D ^b   Ruberto, Amedeo ^b   Girardi, Paolo ^b   Tatarelli, Roberto ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; ANTIHISTAMINIC AGENT; FLURAZEPAM; FLUVOXAMINE; LAMOTRIGINE; LITHIUM; TRAZODONE;

ADULT; BIPOLAR DEPRESSION; BIPOLAR II DISORDER; CASE REPORT; DISEASE EXACERBATION; DRUG ERUPTION; DRUG RECHALLENGE; DRUG TOLERABILITY; DRUG WITHDRAWAL; EOSINOPHILIA; ERYTHEMA; FEMALE; GENERAL CONDITION IMPROVEMENT; HUMAN; HYPOMANIA; LETTER; MONOTHERAPY; PRIORITY JOURNAL; PRURITUS; RETREATMENT; TITRIMETRY;

ANTIMANIC AGENTS; BIPOLAR DISORDER; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXANTHEMA; FEMALE; HUMANS; MIDDLE AGED; TRIAZINES;

EID: 4043049433     PISSN: 13985647     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-5618.2004.00106.x     Document Type: Letter

References (13)

1. Calabrese JR, Bowden CL, Sachs GS, Ascher JA, Monaghan E, Rudd GD. A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. J Clin Psychiatry 1999; 60: 79-88.
2. Calabrese JR, Suppes T, Bowden CL et al. A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. Lamictal 614 Study Group. J Clin Psychiatry 2000; 61: 841-850.
3. Bowden CL, Calabrese JR, Sachs G et al. Lamictal 606 Study Group. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch Gen Psychiatry 2003; 60: 392-400.
4. Barbee JG, Jamhour NJ. Lamotrigine as an augmentation agent in treatment-resistant depression. J Clin Psychiatry 2002; 63: 737-741.
5. Barbosa L, Berk M, Vorster M. A double-blind, randomized, placebo-controlled trial of augmentation with lamotrigine or placebo in patients concomitantly treated with fluoxetine for resistant major depressive episodes. J Clin Psychiatry 2003; 64: 403-407.
6. Normann C, Hummel B, Scharer LO, Horn M, Grunze H, Walden J. Lamotrigine as adjunct to paroxetine in acute depression: a placebo-controlled, double-blind study. J Clin Psychiatry 2002; 63: 337-344.
7. Huang CW, Tsai JJ, Lai ML. Lamotrigine-related skin rashes in adults. Kaohsiung J Med Sci 2002; 18: 566-572.
8. Bhushan M, Brooke R, Hewitt-Symonds M, Craven NM, August PJ. Prolonged toxic epidermal necrolysis due to Lamotrigine. Clin Exp Dermatol 2000; 25: 349-351.
9. Calabrese JR, Sullivan JR, Bowden CL et al. Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. J Clin Psychiatry 2002; 63: 1012-1019.
10. Feliciani C, Verrotti A, Coscione G et al. Skin reactions due to anti-epileptic drugs: several case-reports with long-term follow-up. Int J Immunopathol Pharmacol 2003; 16: 89-93.
11. Besag FM, Ng GY, Pool F. Successful re-introduction of lamotrigine after initial rash. Seizure 2000; 9: 282-286.
12. Tavernor SJ, Wong IC, Newton R, Brown SW. Rechallenge with lamotrigine after initial rash. Seizure 1995; 4: 67-71.
13. Buzan RD, Dubovsky SL. Recurrence of lamotrigine-associated rash with rechallenge. J Clin Psychiatry 1998; 59: 87.