Exogenous interferon-α and interferon-γ increase lethality of murine inhalational anthrax

PLoS ONE

Volumn 2, Issue 8, 2007, Pages

  Gold, Jeffrey A ^a   Hoshino, Yoshihiko ^b   Jones, Marcus B ^c   Hoshino, Satomi ^b   Nolan, Anna ^b   Weiden, Michael D ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c J CRAIG VENTER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; RECOMBINANT ALPHA INTERFERON; RECOMBINANT GAMMA INTERFERON; STAT1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHRAX; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL SPORE; BACTERIAL VIRULENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; FEMALE; IMMUNE RESPONSE; IN VIVO STUDY; INFECTION CONTROL; INFLAMMATION; INNATE IMMUNITY; LETHALITY; LUNG INFECTION; LUNG PARENCHYMA; MORTALITY; MOUSE; NONHUMAN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SPORE GERMINATION;

ADMINISTRATION, INHALATION; ANIMALS; ANTHRAX; BACILLUS ANTHRACIS; FEMALE; HUMANS; INTERFERON-ALPHA; INTERFERON-GAMMA; INTERLEUKINS; LUNG; MAP KINASE KINASE 3; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SPLEEN; SPORES, BACTERIAL; STAT1 TRANSCRIPTION FACTOR; SURVIVAL RATE;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); MURINAE; MUS;

EID: 40349112994     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000736     Document Type: Article

References (34)