New developments in psychosocial interventions for adults with unipolar depression

Current Opinion in Psychiatry

Volumn 21, Issue 1, 2008, Pages 30-36

  Lau, Mark A ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BC Mental Health & Addiction Services   (Canada)

Author keywords

Acute care; Dissemination; Psychotherapy; Relapse prevention; Unipolar depression

Indexed keywords

ANTIDEPRESSANT AGENT; NEFAZODONE; VENLAFAXINE;

CLINICAL TRIAL; COGNITION; COGNITIVE THERAPY; COMMUNITY; DISEASE SEVERITY; EMOTION; EVALUATION; HUMAN; INTERVENTION STUDY; MAINTENANCE THERAPY; MAJOR DEPRESSION; MENTAL HEALTH; MENTAL HEALTH CARE; NEUROBIOLOGY; PSYCHOSOCIAL CARE; PSYCHOTHERAPY; RECURRENCE RISK; RECURRENT DISEASE; RELAPSE; REVIEW; THERAPY EFFECT;

ADULT; AMBULATORY CARE; ANTIDEPRESSIVE AGENTS; CHRONIC DISEASE; COGNITIVE THERAPY; DEPRESSIVE DISORDER; DEPRESSIVE DISORDER, MAJOR; DRUG RESISTANCE; HUMANS; PSYCHOTHERAPY; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RECURRENCE; SEASONAL AFFECTIVE DISORDER; TREATMENT OUTCOME;

EID: 40349110861     PISSN: 09517367     EISSN: None     Source Type: Journal    
DOI: 10.1097/YCO.0b013e3282f1ae53     Document Type: Review

References (45)

1. Elkin I, Shea MT, Watkins JT, et al. NIMH Treatment of Depression Collaborative Research Program: general effectiveness of treatments. Arch Gen Psychiatry 1989; 46:971-982.
2. Thase ME, Friedman ES, Biggs MM, et al. Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: A STAR*D report. Am J Psychiatry 2007; 164:739-752. This is a report of cognitive therapy as a second-step treatment in the largest ever depression treatment study in the USA.
3. Cuijpers P, van Straten A, Warmerdam L. Behavioral activation treatments of depression: a meta-analysis. Clin Psychol Rev 2006; 27:318-326. This review provides data that support behavioral activation as a viable depression treatment.
4. Cuijpers P, van Straten A, Warmerdam L. Problem solving therapies for depression: a meta-analysis. Eur Psychiatry 2007; 22:9-15. This report reveals significant heterogeneity between studies suggesting that further work is necessary to better understand the conditions under which problem-solving therapy is efficacious.
5. de Maat S, Dekker J, Schoevers R, et al. Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: a mega-analysis based on three randomized clinical trials. Depress Anxiety 2007 (epub ahead of print) This analysis pools the data from three separate studies to establish that short psychodynamic supportive psychotherapy is as efficacious as pharmacotherapy or the combination of the two in treating depression.
6. Goldman RN, Greenberg LS, Angus L. The effects of adding emotion-focused interventions to the client-centered relationship conditions in the treatment of depression. Psychother Res 2006; 16:537-549. The design of this trial controls for nonspecific processes and thus evaluates whether emotion-focused treatment is specific in its mechanism of action.
7. Greenberg LS, Watson JC. Experiential therapy of depression: differential effects of client-centered relationship conditions and process experiential interventions. Psychother Res 1998; 8:210-224.
8. Watson JC, Gordon LB, Stermac L, et al. Comparing the effectiveness of process experiential with cognitive-behavioral therapy in the treatment of depression. J Consult Clin Psychol 2003; 71:773-781.
9. Chambless DL, Hollon SD. Defining empirically supported therapies. J Consult Clin Psychol 1998; 66:7-18.
10. Seligman EP, Rashid T, Parks AC. Positive psychotherapy. Am Psychol 2006; 61:774-788. This article introduces a radically different psychological approach to the treatment of depression by increasing positive experience rather than directly targeting depressive symptoms.
11. Strauman TJ, Vieth AZ, Merrill KA, et al. Self-system therapy as an intervention for self-regulatory dysfunction in depression: a randomized comparison with cognitive therapy. J Consult Clin Psychol 2006; 74:367-376. This paper describes and evaluates a translational approach to the development of a new treatment based on regulatory focus theory which derives from research in personality and social psychology.
12. Siegle GJ, Chinassi F, Thase ME. Neurobehavioral therapies in the 21st century: summary of an emerging field and an extended example of cognitive control training for depression. Cogn Ther Res 2007; 31:235-262. This is an example of the integration of neuroscience research findings with psychological treatment research that results in a novel neurobiological approach to designing a psychosocial intervention.
13. DeRubeis RJ, Hollon SD, Amsterdam JD, et al. Cognitive Therapy vs medications in the treatment of moderate to severe depression. Arch Gen Psychiatry 2005; 62:409-416.
14. Luty SE, Carter JD, McKenzie JM, et al. Randomized controlled trial of interpersonal psychotherapy and cognitive-behavioural therapy for depression. Br J Psychiatry 2007; 190:496-502. This study was designed to address the controversy regarding the use of CBT and IPT in treating severe depression. In addition to showing that CBT, but not IPT, was efficacious in treating severe depression, there was evidence that both CBT and IPT were efficacious for melancholic depression.
15. Dimidjian S, Hollon SD, Dobson KS, et al. Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression. J Consult Clin Psychol 2006; 74:658-670. This trial was important as it demonstrates that behavioral activation is at least as effective as pharmacotherapy in treating severe depression. Thus, it supports behavioral activation as a viable alternative to pharmacotherapy. Furthermore, behavioral activation may be easier to implement and train than other more complex interventions.
16. Kenny MA, Williams JMG. Treatment-resistant depressed patients show a good response to mindfulness-based cognitive therapy. Behav Res Ther 2007; 45:617-625. This study is important for two reasons. First, it establishes that MBCT may be a useful treatment in this population, which is contrary to earlier predictions that MBCT might not be effective in depressed patients. Second, it also provides pilot data that MBCT can reduce depressive symptoms for patients in the unremitted depressive phase of bipolar disorder.
17. Segal ZV, Williams JMG, Teasdale JD. Mindfulness-based Cognitive Therapy for depression: a new approach for preventing relapse. New York: Guilford; 2002.
18. Kabat-Zinn J. Full catastrophe living: using the wisdom of your mind to face stress, pain and illness. New York: Dell Publishing; 1990.
19. Jacobson NS, Martell CR, Dimidjian S. Behavioural activation treatment for depression: returning to contextual roots. Clin Psychol Sci Practice 2001; 8:255-270.
20. Nolen-Hoeksema S. The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. J Ab Psychol 1991; 109:504-511.
21. Teasdale JD, Segal ZV, Williams JMG, et al. Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. J Consult Clin Psychol 2000; 68:615-623.
22. Rohan KJ, Roecklein KA, Lindsey K, et al. A randomized controlled trial of cognitive-behavioral therapy, light therapy, and their combination for seasonal affective disorder. J Consult Clin Psychol 2007; 75:489-500. This is the first RCT comparing CBT with light therapy. This study establishes CBT as a viable treatment option in the treatment of seasonal affective disorder.
23. Frank E, Kupfer DJ, Perel JM, et al. Three-year outcomes for maintenance therapies in recurrent depression. Arch Gen Psychiatry 1990; 47:1093-1099.
24. Judd LJ. The clinical course of unipolar major depressive disorders. Arch Gen Psychiatry 1997; 54:989-991.
25. Hollon SD, DeRubeis RJ, Shelton RC, et al. Prevention of relapse following cognitive therapy vs medications in moderate to severe depression. Arch Gen Psychiatry 2005; 62:417-422.
26. Blackburn LM, Eunson KM, Bishop S. A two-year naturalistic follow-up of depressed patients treated with cognitive therapy, pharmacotherapy, and a combination of both. J Affect Disorders 1986; 10:67-75.
27. Evans JD, Hollon SD, DeRubeis RJ, et al. Differential relapse following cognitive therapy and pharmacotherapy for depression. Arch Gen Psychiatry 1992; 49:802-808.
28. Shea MT, Elkin I, Imber SD, et al. Course of depressive symptoms over follow-up: findings from the NIMH Treatment of Depression Collaborative Research Program. Arch Gen Psychiatry 1992; 49:782-787.
29. Simons AD, Murphy GE, Levine JL, Wetzel RD. Cognitive therapy and pharmacotherapy for depression: sustained improvement over one year. Arch Gen Psychiatry 1986; 43:43-50.
30. Kupfer DJ, Frank E, Perel JM, et al. Five-year outcome for maintenance therapies in recurrent depression. Arch Gen Psychiatry 1992; 49:769-773.
31. Jarrett RB, Kraft D, Doyle J, et al. Preventing recurrent depression using cognitive therapy with and without a continuation phase: a randomised clinical trial. Arch Gen Psychiatry 2001; 58:381-388.
32. Frank E, Kupfer DJ, Buysse DJ, et al. Randomized trial of weekly, twice-monthly, and monthly interpersonal psychotherapy as maintenance treatment for women with recurrent depression. Am J Psychiatry 2007; 164:761-767. This parametric analysis of the required frequency of maintenance therapy sessions established that monthly sessions were sufficient to prevent depressive relapse/recurrence.
33. Klein DN, Santiago NJ, Vivian D, et al. Cognitive-behavioral analysis system of psychotherapy as a maintenance treatment for chronic depression. J Consult Clin Psychol 2004; 72:681-688.
34. Ma SH, Teasdale JD. Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects. J Consult Clin Psychol 2004; 72:31-40.
35. Bockting CLH, Schene AH, Spinhoven P, et al. Preventing relapse/recurrence in recurrent depression with cognitive therapy: a randomized controlled trial. J Consult Clin Psychol 2005; 73:647-657.
36. Paykel ES. Cognitive therapy in relapse prevention in depression. Int J Neuropsychopharmacol 2007; 10:131-136. This is a comprehensive review of the effectiveness of a variety of cognitive-based psychosocial interventions for the prevention of depressive relapse, a summary of the findings and a discussion of the possible mechanisms underlying the effectiveness of these interventions.
37. National Institute for Clinical Excellence. Depression: management of depression in primary and secondary care, Clinical Guideline 23. London: National Institute for Clinical Excellence. 2004.
38. Van Straten A, Tiemens B, Hakkaart L, et al. Stepped care vs. matched care for mood and anxiety disorders: a randomized trial in routine practice. Acta Psychiatr Scand 2006; 113:468-476. This paper describes the evaluation of the stepped care model which has important implications with respect to future dissemination efforts.
39. Kates N, Mach M. Chronic disease management for depression in primary care: a summary of the current literature and implications for practice. Can J Psychiatry 2007; 52:77-85. This is an excellent review of outcome studies that includes specific recommendations for the integration of elements of this model in primary care.
40. Gilbody S, Bower P, Fletcher J, et al. Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes. Arch Intern Med 2006; 166:2314-2321. An excellent and comprehensive review of the outcome studies with sub-analyses of the impact of study setting, intervention content and medication compliance on outcome.
41. Brody AL, Saxena S, Stoessel P, et al. Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: preliminary findings. Arch Gen Psychiatry 2001; 58:631-640.
42. Martin SD, Martin E, Rai SS, et al. Brain blood flow changes in depressed patients treated with interpersonal psychotherapy or venlafaxine hydrochloride: preliminary findings. Arch Gen Psychiatry 2001; 58:641-648.
43. Goldapple K, Segal Z, Garson C, et al. Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy. Arch Gen Psychiatry 2004; 61:34-41.
44. Kennedy SH, Konarski JZ, Segal ZV, et al. Differences in brain glucose metabolism between responders to CBT and venlafaxine in a 16-week randomized controlled trial. Am J Psychiatry 2007; 164:778-788. The first well-designed neuroimaging study to demonstrate the neurobiological impact of psychotherapy.
45. Antonuccio DO, Thomas M, Danton WG. A cost-effectiveness analysis of cognitive-behavioural therapy and fluoxetine (prozac) in the treatment of depression: cost-effectiveness, cost-benefits, and quality of life. Behav Ther 1997; 28:187-210.