Dual repressive effect of angiotensin II-type 1 receptor blocker telmisartan on angiotensin II-induced and estradiol-induced uterine leiomyoma cell proliferation

Human Reproduction

Volumn 23, Issue 2, 2008, Pages 440-446

  Isobe, Aki ^a,b   Takeda, Takashi ^a,c   Sakata, Masahiro ^a   Miyake, Asako ^a   Yamamoto, Toshiya ^b   Minekawa, Ryoko ^a   Nishimoto, Fumihito ^a   Oskamoto, Yoko ^a   Walker, Cheryl Lyn ^d   Kimura, Tadashi ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SAKAI MUNICIPAL HOSPITAL   (Japan)

^c OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

Angiotensin II; Angiotensin II type 1 receptor blocker; Signal transduction; Telmisartan; Uterine leiomyoma

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTRADIOL; JANUS KINASE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE C; TELMISARTAN; ANGIOTENSIN 1 RECEPTOR; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA TRANSFECTION; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL STUDY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE; TUMOR CELL; UTERUS MYOMA; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED DISORDER; LEIOMYOMA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; UTERUS CANCER;

RATTUS;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZIMIDAZOLES; BENZOATES; CELL LINE, TUMOR; CELL PROLIFERATION; ESTRADIOL; FEMALE; LEIOMYOMA; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; SIGNAL TRANSDUCTION; UTERINE NEOPLASMS;

EID: 40349106045     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dem247     Document Type: Article

References (30)