Analysis of polymorphisms in the 3′ untranslated region of the LDL receptor gene and their effect on plasma cholesterol levels and drug response

International Journal of Molecular Medicine

Volumn 21, Issue 3, 2008, Pages 345-353

  Chen, Wei ^a   Wang, Shukui ^b   Ma, Yuling ^b   Zhou, Yue ^a   Liu, Haiyan ^a   Strnad, Pavel ^a   Kraemer, Fredric B ^a   Krauss, Ronald M ^c   Liu, Jingwen ^a  

^a VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^b NANJING MEDICAL UNIVERSITY   (China)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

3 untranslated region; Berberine; Genetic variants; LDL receptor; MRNA stability; Single nucleotide polymorphism

Indexed keywords

BERBERINE; CHOLESTEROL; GENOMIC DNA; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; LUCIFERASE; MESSENGER RNA;

3' UNTRANSLATED REGION; ADULT; AGED; ARTICLE; CELL STRAIN HEPG2; CHINESE; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION FUNCTION; DNA ISOLATION; DRUG RESPONSE; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPORTER GENE; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 40249120101     PISSN: 11073756     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijmm.21.3.345     Document Type: Article

References (21)