A study on mRNA expressions of interleukin 10 during fracture healing for wound age determination

Legal Medicine

Volumn 10, Issue 3, 2008, Pages 131-137

  Takamiya, Masataka ^a   Fujita, Sachiko ^a   Saigusa, Kiyoshi ^a   Aoki, Yasuhiro ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Fracture; In situ hybridization; Interleukin 10; Quantitative PCR; Wound aging

Indexed keywords

INTERLEUKIN 10; MESSENGER RNA;

AGE DETERMINATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CALLUS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FRACTURE HEALING; INFLAMMATORY CELL; LYMPHOCYTIC INFILTRATION; MACROPHAGE MIGRATION; MESSENGER RNA SYNTHESIS; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OSTEOBLAST; OSTEOCYTE; PROTEIN EXPRESSION; T LYMPHOCYTE; WOUND ASSESSMENT;

ANIMALS; B-LYMPHOCYTES; CELL PROLIFERATION; FORENSIC PATHOLOGY; FRACTURE HEALING; FRACTURES, BONE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERLEUKIN-10; MACROPHAGES; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; NEUTROPHILS; OSTEOBLASTS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES; TIME FACTORS;

EID: 40249088142     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.legalmed.2007.11.003     Document Type: Article

References (22)

1. Hernandez-Cueto C., Girela E., and Sweet D.J. Advances in the diagnosis of wound vitality: a review. Am J Forensic Med Pathol 21 (2000) 21-31
2. Ohshima T. Forensic wound examination. Forensic Sci Int 113 (2000) 153-164
3. Takamiya M., Saigusa K., Nakayashiki N., and Aoki Y. Studies on mRNA expression of basic fibroblast growth factor in wound healing for wound age determination. Int J Legal Med 117 (2003) 46-50
4. Takamiya M., Saigusa K., Kumagai R., Nakayashiki N., and Aoki Y. Studies on mRNA expression of tissue-type plasminogen activator in bruises for wound age estimation. Int J Legal Med 119 (2005) 16-21
5. Takamiya M., Kumagai R., Nakayashiki N., and Aoki Y. A study on mRNA expressions of fibronectin in dermal and cerebral wound healing for wound age estimation. Leg Med 8 (2006) 214-219
6. Raekallio J., and Makinen P.L. Alkaline and acid phosphatase activity in the initial phase of fracture healing. Acta Pathol Microbiol Scand 75 (1969) 415-422
7. Raekallio J., and Kovacs M. Adenosine triphosphatase activity in the initial phase of fracture healing. A histochemical study on rats. Acta Morphol Acad Sci Hung 17 (1969) 41-46
8. Sherry R.M., Cue J.I., Goddard J.K., Parramore J.B., and DiPiro J.T. Interleukin-10 is associated with the development of sepsis in trauma patients. J Trauma 40 (1996) 613-616
9. Smith R.M., Giannoudis P.V., Bellamy M.C., Perry S.L., Dickson R.A., and Guillou P.J. Interleukin-10 release and monocyte human leukocyte antigen-DR expression during femoral nailing. Clin Orthop 373 (2000) 233-240
10. Lyons A., Kelly J.L., Rodrick M.L., Mannick J.A., and Lederer J.A. Major injury induces increased production of interleukin-10 by cells of the immune system with a negative impact on resistance to infection. Ann Surg 226 (1997) 450-458
11. Napolitano L.M., Koruda M.J., Meyer A.A., and Baker C.C. The impact of femur fracture with associated soft tissue injury on immune function and intestinal permeability. Shock 5 (1996) 202-207
12. Bonnarens F., and Einhorn T.A. Production of a standard closed fracture in laboratory animal bone. J Orthop Res 2 (1984) 97-101
13. Chomczynski P., and Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
14. Hauser C.J., Joshi P., Zhou X., Kregor P., Hardy K.J., Devidas M., et al. Production of interleukin-10 in human fracture soft-tissue hematomas. Shock 6 (1996) 3-6
15. Ohshima T., and Sato Y. Time-dependent expression of interleukin 10 (IL 10) mRNA during the early phase of skin wound healing as a possible indicator of wound vitality. Int J Legal Med 111 (1998) 251-255
16. Moore K.W., de Waal Malefyt R., Coffman R.L., and O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 19 (2001) 683-765
17. Mazighi M., Pelle A., Gonzalez W., Mtairag el M., Philippe M., Henin D., et al. IL-10 inhibits vascular smooth muscle cell activation in vitro and in vivo. Am J physiol heart circ physiol 287 (2004) H866-H871
18. de Waal Malefyt R., Abrams J., Bennett B., Figdor C.G., and Vries J.E.D. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174 (1991) 1209-1220
19. Verhoef C.M., van Roon J.A., Vianen M.E., Bijlsma J.W., and Lafeber F.P. Interleukin 10 (IL-10), not IL-4 or interferon-gamma production, correlates with progression of joint destruction in rheumatoid arthritis. J Rheumatol 28 (2001) 1960-1966
20. de Waal Malefyt R., Haanen J., Spits H., Roncarolo M.G., te Velde A., Figdor C., et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 174 (1991) 915-924
21. Seibel R., LaDuca J., Hassett J.M., Babikian G., Mills B., Border D.O., et al. Blunt multiple trauma (ISS 36), femur traction, and the pulmonary failure-septic state. Ann Surg 202 (1985) 283-295
22. Dresner-Pollak R., Gelb N., Rachmilewitz D., Karmeli F., and Weinreb M. Interleukin 10-deficient mice develop osteopenia, decreased bone formation, and mechanical fragility of long bones. Gastroenterology 127 (2004) 792-801