Simultaneous quantitation of theophylline and guaifenesin in syrup by HPLC, derivative and derivative ratio spectrophotometry for quality control purposes

Iranian Journal of Pharmacology and Therapeutics

Volumn 5, Issue 1, 2006, Pages 67-72

  Ansari, Mehdi ^a   Kazemipour, Maryam ^b   Shahriar, Mohammad ^a  

^a KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Derivative; Derivative Ratio; Guaifenesin; HPLC; Spectrophotometry; Theophylline

Indexed keywords

CAFFEINE; GUAIFENESIN; METHANOL; POTASSIUM DIHYDROGEN PHOSPHATE; SODIUM HYDROXIDE; THEOPHYLLINE;

ARTICLE; COST BENEFIT ANALYSIS; DRUG ABSORPTION; DRUG DETERMINATION; DRUG MIXTURE; DRUG SYNTHESIS; DRUG USE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; QUALITY CONTROL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SPECTROPHOTOMETRY; SYRUP;

EID: 40149111382     PISSN: 17352657     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Hardman JG, Limbird LE, Gilman AG. Goodman & Gilman's The Pharmacological Basis of Therapeutics, tenth ed. McGraw-Hill Professional, NY, 2001.
2. USP28-NF23, the United States Pharmacopoeial Convention, Inc., Twin brook Parkway, 2005.
3. BP 2004, the Stationary Office, London, 2004.
4. Indrayanto G, Sunarto A, Adriani Y. Simultaneous assay of phenylpropanolamine hydrochloride, caffeine, paracetamol, glycerylguaiacolate and chlorpheniramine in Silabat™ tablet using HPLC with diode array detection. J Pharm Biomed Anal. 1995;13:1555-9.
5. Nakashima K, Inoue K, Mayahara K, Kuroda N, Hamachi Y, Akiyama S. Use of 3-(1,8-naphthalimido) propyl-modified silyl silica gel as a stationary phase for the high-performance liquid chromatographic separation of purine derivatives. J Chromatogr A. 1996;722:107-13.
6. Vogt C, Conradi S, Rohde E, Determination of caffeine and other purine compounds in food and pharmaceuticals by micellar electrokinetic chromatography. J Chem Educ. 1997;74:1126-30.
7. Ni Y, Zhang G, Kokot S. Simultaneous spectrophotometric determination of maltol, ethyl maltol, vanillin and ethyl vanillin in foods by multivariate calibration and artificial neural networks. Food Chemistry. 2005;89: 465-73.
8. Morelli B. Derivative spectrophotometry in the analysis of mixtures of cefotaxime sodium and cefadroxil monohydrate. J Pharm Biomed Anal. 2003;32:257-67.
9. Kazemipour M, Noroozian E, Tehrani MS, Mahmoudian M, A new second-derivative spectrophotometric method for the determination of permethrin in shampoo. J Pharm Biomed Anal. 2002;30:1379-84.
10. Yilmaz B, Öztürk M, Kadiolu Y. Comparison of two derivative spectrophotometric methods for the determination of α-tocopherol in pharmaceutical preparations. Il Farmaco. 2004;59:723-7.
11. Oliveira EJ, Watson DG, Morton NS. A simple microanalytical technique for the determination of paracetamol and its main metabolites in blood spots J Pharm Biomed Anal. 2002;29:803-9.
12. Rasmussen BB, Brosen K. Determination of theophylline and its metabolites in human urine and plasma by high-performance liquid chromatography. J.Chromatogr B. 1996;676:169-74.
13. Schreiber-Deturmeny E, Bruguerolle B. Simultaneous high-performance liquid chromatographic determination of caffeine and theophylline for routine drug monitoring in human plasma. J Chromatogr B. 1996;677:305-12.
14. Gaillard Y, Pépin G. Use of high-performance liquid chromatography with photodiode-array UV detection for the creation of a 600-compound library. Application to forensic toxicology. J Chromatogr A. 1997;763:149-63.
15. Stavchansky S, Demirbas S, Reyderman L, Chai CK. Simultaneous determination of dextromethorphan and guaifenesin in human plasma by liquid chromatography with fluorescence detection. J Pharm Biomed Anal. 1995;13:919-25.
16. Dinc E, Kdil GK, Onur F. Derivative ratio spectra-zero crossing spectrophotometry and LC method applied to the quantitative determination of paracetamol, propyphenazone and caffeine in ternary mixtures. J Pharm Biomed Anal. 2001;26:769-78.
17. Karpinski J, Mularczyk B. The analysis of the zero-order and the second derivative spectra of retinol acetate, tocopherol acetate and coenzyme Q10 and estimation of their analytical usefulness for their simultaneous determination in synthetic mixtures and pharmaceuticals. Spectrochimica Acta Part A. 2004;60:2189-94.
18. Dinc E. A comparative study of the ratio spectra derivative spectrophotometry, Vierordt's method and high-performance liquid chromatography applied to the simultaneous analysis of caffeine and paracetamol in tablets. J Pharm Biomed Anal. 1999;21:723-30.
19. Mahgoub H, Gazy AA, El-Yazbi FA, El-Sayed MA, Youssef RM. Spectrophotometric determination of binary mixtures of pseudoephedrine with some histamine H1-receptor antagonists using derivative ratio spectrum method. J Pharm Biomed Anal. 2003;31:801-9.