I-123 MIBG cardiac scintigraphy and autonomic test evaluation in multiple sclerosis patients

Journal of Neurology

Volumn 255, Issue 2, 2008, Pages 211-216

  Lorberboym, M ^a   Lampl, Y ^a   Nikolov, G ^a   Sadeh, M ^a   Gilad, R ^a  

^a WOLFSON MEDICAL CENTER   (Israel)

Author keywords

Autonomic function; Cardiac; I 123 MIBG; Multiple sclerosis; Relapsing remitting (R R); Secondary progressive (SP); SPECT

Indexed keywords

(3 IODOBENZYL)GUANIDINE;

ADULT; ARTICLE; AUTONOMIC DENERVATION; AUTONOMIC DYSFUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ELECTROPHYSIOLOGY; FEMALE; FOLLOW UP; HEART FUNCTION; HEART SCINTISCANNING; HUMAN; MALE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INJURY; PRIORITY JOURNAL; RATING SCALE; RELAPSE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

3-IODOBENZYLGUANIDINE; ADULT; AUTONOMIC NERVOUS SYSTEM; FEMALE; HEART; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; PARASYMPATHETIC NERVOUS SYSTEM; RADIOPHARMACEUTICALS; SYMPATHETIC NERVOUS SYSTEM; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 40149107120     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-008-0652-x     Document Type: Article

References (25)

1. Beer M, Sandstede J, Weilbach F, Spindler M, Buchner S, Krug A, Kostler H, Pabst T, Kenn W, Landschutz W, Von Kielin M (2001) Cardiac metabolism and function in patients with multiple sclerosis: a combined 31P-MR-spectroscopy and MRI study. Rofo 173:399-404
2. Braune S, Reinhardt M, Bathmann J, Krause T, Lethmann M, Lucking CH (1998) Impaired cardiac uptake of meta-[123I] iodobenzylguanidine in Parkinson's disease with autonomic failure. Acta Neurol Scand 97:307-314
3. Choi JY, Lee KH, Hong KP, Kim BT, Sev JD, Lee WR, Lee SH (2001) Iodine-123 MIBG imaging before treatment of heart failure with carvedilol to predict improvement of left ventricular function and exercise capacity. J Nucl Cardiol 8:4-9
4. de-Seze J, Stojkovic T, Gauvrit JY, Devos D, Ayachi M, Cassim F, Faint Michel T, Pruvo JP, Gviev JD, Vermersch P (2001) Autonomic dysfunction in multiple sclerosis: cervical spinal cord atrophy correlates. J Neurol 248:297-303
5. Fowler C, Henry M (1996) Gastrointestinal dysfunction in multiple sclerosis. Semin Neurol 16:277-279
6. Gunal DI, Afsar N, Tahniday T, Aktan S (2002) Autonomic dysfunction in multiple sclerosis: correlation with disease-related parameters. Eur Neurol 48(1):1-5
7. Haensch CA, Jong J (2006) Autonomic dysfunction in multiple sclerosis. J Neurol 253(Suppl I):I3-I9
8. Hattori N, Tamaki N, Hayashi T, Masuda I, Kudoh T, Tateno M, Tadamuna E, Yonekura Y, Nakao K, Konishi J (1996) Regional abnormality of iodine-123-MIBG in diabetic hearts. J Nucl Med 37:1985-1990
9. Henderson EB, Kahn JK, Corbett JR, Jansen DE, Pippin JJ, Kuldarni P, Vgolini V, Akers MS, Hansen C, Buja LM, et al. (1988) Abnormal I-123 metaiodobenzylguanidine myocardial washout and distribution may reflect myocardial adrenergic derangement in patients with congestive cardiomyopathy. Circulation 78:1192-1199
10. Kashihara K, Yamamoto M (2006) Myocardial (123)-MIBG scintigraphy in patients with PSP, CBD and MSA. J Neurol 253(Suppl 3):11B5-11B40
11. Kline RC, Swanson DP, Wieland DM, Thrall JH, Gross MD, Pitt B, Beierwalter WH (1981) Myocardial imaging in man with I-123 meta- iodobenzylguanidine. J Nucl Med 22:129-132
12. Kodounis A, Stamboulis E, Constantinidis TS, Liolios A (2005) Measurement of autonomic dysregulation in multiple sclerosis. Acta Neurol Scand 112:403-408
13. Kurtzke JE (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33:1444-1452
14. Flachenecker P, Reiners K, Krauser M, Wolf A, Toyka KV (2001) Autonomic dysfunction in multiple sclerosis is related to disease activity and progression of disability. Mult Scler 7(5):327-334
15. McDougall AJ, McLoad JG (2003) Autonomic nervous system function in multiple sclerosis. J Neurol Sci 215:79-85
16. Merlet P, Valette H, Dubois-Rande JL, Moyse D, Duboc D, Dove P, Bourgvignon MH, Benevenuti C, Duval AM, Agostini D, et al. (1992) Prognostic value of cardiac metaiodobenzylguanidine imaging in patients with heart failure. J Nucl Med 33:471-477
17. Morimoto S, Terada K, Keira N, Satoda M, Inoue K, Tatsukawa H, Katoh S, Ida K, Sugihara H, Takeda K, Nakajawa M (1996) Investigation of the relationship between regression of hypertensive cardiac hypertrophy and improvement of cardiac sympathetic nervous system dysfunction using iodine-123 metaiodobenzylguanidine myocardial imaging. Eur J Nucl Med 23:756-761
18. Nagamachi S, Jinnouchi S, Kurose T, Ohnishi T, Flores LG 2nd, Nakahara H, Futami S, Tamun S, Matsukuna S (1998) I-123 MIBG myocardial scintigraphy in diabetic patients: relationship with 201TI uptake and cardiac autonomic function. Ann Nucl Med 12:323-331
19. Poser CM, Paty DW, Scheinberg C (1983) New diagnostic criteria for multiple sclerosis. Guidelines for research protocols. Ann Neurol 13:227-231
20. Raum W, Laks M, Garner D, Swerdloff R (1983) Beta-adrenergic receptor and cyclic AMP alterations in the canine ventricular septum during long-term norepinephrine infusion: implications for hypertrophic cardiomyopathy. Circulation 68:693-699
21. Saari A, Tolonen U, Paakko E, Svominen K, Pyhtinen J, Sotaniemi K, Myllyla V (2004) Cardiovascular autonomic dysfunction correlates with brain MRI lesion load in MS. Clin Neurophysiol 115:1473-1478
22. Scofer J, Spielmann R, Schuchert A, Weber K, Schluter M (1988) Iodine-123 meta-iodobenzylguanidine scintigraphy: a noninvasive method to demonstrate myocardial adrenergic nervous system disintegrity in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 12:1252-1258
23. Simpson P (1985) Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of heating through an alpha 1- and beta 1- adrenergic receptor interaction: evidence for independent regulation of growth and beating. Circ Res 56:884-894
24. Stalberg EV, Nogues MA (1989) Autonomic analysis of heart rate variation: I Method and reference values in healthy controls. Muscle and Nerve 12:993-1000
25. Valette H, Srota A (1998) Nuclear techniques in the assessment of myocardial innervation. In:Murry IPC (ed) Nuclear medicine in clinical diagnosis and treatment. Churchill Livingstone, pp 1525-1529