Expression of amyloid beta peptide in human platelets: Pivotal role of the phospholipase Cγ2-protein kinase C pathway in platelet activation

Pharmacological Research

Volumn 57, Issue 2, 2008, Pages 151-158

  Shen, Ming Yi ^a   Hsiao, George ^a   Fong, Tsorng Han ^b   Chou, Duen Suey ^a   Sheu, Joen Rong ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Amyloid ; Free radicals; Phospholipase C; Platelet aggregation; Protein kinase C

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[25-35]; CALCIUM; COLLAGEN; HYDROXYL RADICAL; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPASE C GAMMA2; PROTEIN KINASE C;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; DRUG DISTRIBUTION; ELECTRON SPIN RESONANCE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LATENT PERIOD; MESENTERIC VEIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STIMULATION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOGENESIS;

AMYLOID BETA-PROTEIN; ANALYSIS OF VARIANCE; ANIMALS; BLOOD PLATELETS; CALCIUM; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROXYL RADICAL; INDOLES; MICE; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROTEIN KINASE C;

EID: 40149104924     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2008.01.004     Document Type: Article

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