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Volumn 8, Issue 1, 2008, Pages 36-45
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Bacterial β-ketoacyl-acyl carrier protein synthase III (FabH): An attractive target for the design of new broad-spectrum antimicrobial agents
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Author keywords
Drug design; FabH; FabH inhibitors; FAS
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Indexed keywords
1,2 DITHIOLE 3 ONE DERIVATIVE;
3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE;
ANTIBIOTIC AGENT;
ANTIINFECTIVE AGENT;
BACTERIAL PROTEIN;
BENZOYLAMINOBENZOIC ACID;
DACTINOMYCIN;
DICHLOROBENZYLOXY INDOLE CARBOXYLIC ACID INHIBITOR;
INDOLE INHIBITOR;
LINEZOLID;
OXAZOLIDINONE DERIVATIVE;
THIOLACTOMYCIN;
THIOLACTOMYCIN DERIVATIVE;
UNCLASSIFIED DRUG;
ANTIBIOTIC RESISTANCE;
ANTIBIOTIC SENSITIVITY;
BACTERIAL STRAIN;
CRYSTAL STRUCTURE;
CRYSTALLOGRAPHY;
DRUG DESIGN;
DRUG POTENCY;
DRUG SCREENING;
DRUG SOLUBILITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
DRUG TARGETING;
ENZYME BINDING;
ENZYME INHIBITION;
ENZYME SPECIFICITY;
ENZYME STRUCTURE;
ENZYME SUBSTRATE;
FATTY ACID SYNTHESIS;
HIGH THROUGHPUT SCREENING;
HUMAN;
IC 50;
INFECTION;
MINIMUM INHIBITORY CONCENTRATION;
NONHUMAN;
REVIEW;
STRUCTURE ACTIVITY RELATION;
VIRTUAL REALITY;
3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE;
ANTI-INFECTIVE AGENTS;
BACTERIA;
DRUG DESIGN;
ENZYME INHIBITORS;
HUMANS;
MODELS, BIOLOGICAL;
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EID: 40049109991
PISSN: 13895575
EISSN: None
Source Type: Journal
DOI: 10.2174/138955708783331559 Document Type: Review |
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Times cited : (21)
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References (79)
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