p21-LacZ reporter mice reflect p53-dependent toxic insult

Toxicology and Applied Pharmacology

Volumn 227, Issue 3, 2008, Pages 440-450

  Vasey, Douglas B ^a   Wolf, C Roland ^b,c   MacArtney, Thomas ^c   Brown, Ken ^c   Whitelaw, C Bruce A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c CXR Biosciences Ltd   (United Kingdom)

Author keywords

Cell cycle; Drug; Etoposide; Hippocampus; Toxicity; Transgenic mice

Indexed keywords

BETA GALACTOSIDASE; PROTEIN P21; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL GROWTH; DRUG TOXICITY; ENZYME ACTIVATION; GENE ACTIVATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; BETA-GALACTOSIDASE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DRUG EVALUATION, PRECLINICAL; DRUG TOXICITY; GENE EXPRESSION; GENES, REPORTER; MICE; MICE, TRANSGENIC; RNA, MESSENGER; TISSUE DISTRIBUTION; TRANSGENES; TUMOR SUPPRESSOR PROTEIN P53;

MUS; MUS MUSCULUS;

EID: 40049104031     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.11.029     Document Type: Article

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