The vitamin E analog tocopherol succinate strongly inhibits gap junctional intercellular communication in rat liver epithelial cells (IAR203)

Journal of Nutritional Biochemistry

Volumn 19, Issue 4, 2008, Pages 263-268

  Chaumontet, Catherine ^a   Bex, Valérie ^a   Véran, Frédéric ^a   Martel, Paule ^a  

^a CEMAGREF   (France)

Author keywords

Connexin 43; Gap junction; Liver cells; Tocopherol succinate; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOPHEROL PHOSPHATE; ALPHA TOCOPHEROL SUCCINATE; CONNEXIN 43; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL COMMUNICATION; CONTROLLED STUDY; DRUG EFFECT; EPITHELIUM CELL; GAP JUNCTION; NONHUMAN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT;

RATTUS;

EID: 40049103962     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.03.005     Document Type: Article

References (50)

1. C.K. Chow Biological functions and metabolic fate of vitamin E revisited J Biomed Sci 11 2004 295 302
2. C. Schneider Chemistry and biology of vitamin E Mol Nutr Food Res 49 2005 7 30
3. R. Ricciarelli J.M. Zingg A. Azzi Vitamin E: protective role of a Janus molecule FASEB J 15 2001 2314 2325
4. X.Y. Wang P.J. Quinn The location and function of vitamin E in membranes Mol Membr Biol 17 2000 143 156
5. J. Neuzil M. Tomasetti A.S. Mellick R. Alleva B.A. Salvatore M. Birringer Vitamin E analogues: a new class of inducers of apoptosis with selective anticancer effects Curr Cancer Drug Targets 4 2004 355 372
6. A. Dutta S.K. Dutta Vitamin E and its role in the prevention of atherosclerosis and carcinogenesis: a review J Am Coll Nutr 22 2003 258 268
7. J.M. Tucker D.M. Townsend Alpha-tocopherol: roles in prevention and therapy of human disease Biomed Pharmacother 59 2005 380 387
8. D.Q. Pham R. Plakogiannis Vitamin E supplementation in cardiovascular disease and cancer prevention: Part 1 Ann Pharmacother 39 2005 1870 1878
9. J. Neuzil Vitamin E succinate and cancer treatment: a vitamin E prototype for selective antitumour activity Br J Cancer 89 2003 1822 1826
10. K.N. Prasad B. Kumar X.D. Yan A.J. Hanson W.C. Cole Alpha-tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment: a review J Am Coll Nutr 22 2003 108 117
11. W.R. Loewenstein Junctional intercellular communication: the cell-to-cell membrane channel Physiol Rev 61 1981 829 913
12. G.E. Sosinsky B.J. Nicholson Structural organization of gap junction channels Biochim Biophys Acta 1711 2005 99 125
13. D.B. Alexander G.S. Goldberg Transfer of biologically important molecules between cells through gap junction channels Curr Med Chem 10 2003 2045 2058
14. D. Segretain M.A. Falk Regulation of connexin biosynthesis, assembly, gap junction formation, and removal Biochim Biophys Acta 1662 2004 3 21
15. M. Nishi N.M. Kumar N.B. Gilula Developmental regulation of gap junction gene expression during mouse embryonic development Dev Biol 146 1991 117 130
16. F.D. Houghton Role of gap junctions during early embryo development Reproduction 129 2005 129 135
17. W.R. Loewenstein Junctional intercellular communication and the control of growth Biochim Biophys Acta 560 1979 1 65
18. M. Vinken T. Vanhaecke P. Papeleu S. Snykers T. Henkens V. Rogiers Connexins and their channels in cell growth and cell death Cell Signal 18 2006 592 600
19. J.E. Trosko B.V. Madhukar C.C. Chang Endogenous and exogenous modulation of gap junctional intercellular communication: toxicological and pharmacological implications Life Sci 53 1993 1 19
20. M. Mesnil Connexins and cancer Biol Cell 94 2002 493 500
21. T. Enomoto Y. Sasaki Y. Shiba Y. Kanno H. Yamasaki Tumor promoters cause a rapid and reversible inhibition of the formation and maintenance of electrical cell coupling in culture Proc Natl Acad Sci U S A 1981 785628 785632
22. V. Valiunas J.F. Bechberger C.C.G. Naus P.R. Brink G.S. Goldberg Nontransformed cells can normalize gap junctional communication with transformed cells Biochem Biophys Res Commun 333 2005 174 179
23. J.E. Trosko R.J. Ruch Gap junctions as targets for cancer chemoprevention and chemotherapy Curr Drug Targets 3 2002 465 482
24. X. Guan J. Hardenbrook M.J. Fernstrom R. Chaudhuri A.M. Malkinson R.J. Ruch Down-regulation by butylated hydroxytoluene of the number and function of gap junctions in epithelial cell lines derived from mouse lung and rat liver Carcinogenesis 16 1995 2575 2582
25. H. Yamasaki J. Ashby M. Bignami W. Jongen K. Linnainmaa R.F. Newbold Nongenotoxic carcinogens: development of detection methods based on mechanisms: a European project Mutat Res 353 1996 47 63
26. C. Huard N. Druesne D. Guyonnet M. Thomas A. Pagniez A.M. LeBon Diallyl disulfide (DADS) enhances gap-junctional intercellular communication by both direct and indirect mechanisms in rat liver cells Carcinogenesis 25 2004 91 98
27. J.S. Bertram Dietary carotenoids, connexins and cancer: what is the connection? Biochem Soc Trans 32 2004 985 989
28. T. Enomoto N. Martel Y. Kanno H. Yamasaki Inhibition of cell communication between Balb/c 3T3 cells by tumor promoters and protection by cAMP J Cell Physiol 121 1984 323 333
29. O.H. Lowry N.J. Rosebrough A.L. Farr R.J. Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265 275
30. V. Bex T. Mercier C. Chaumontet I. Gaillard-Sanchez B. Flechon F. Mazet Retinoic acid enhances connexin43 expression at the post-transcriptional level in rat liver epithelial cells Cell Biochem Funct 13 1995 69 77
31. W. Cohn Bioavailability of vitamin E Eur J Clin Nutr 51 1997 S80 S85
32. T. Enomoto H. Yamasaki Phorbol ester-mediated inhibition of intercellular communication in BALB/c 3T3 cells: relationship to enhancement of cell transformation Cancer Res 45 1985 2681 2688
33. E. Rivedal E. Leithe Connexin43 synthesis, phosphorylation, and degradation in regulation of transient inhibition of gap junction intercellular communication by the phorbol ester TPA in rat liver epithelial cells Exp Cell Res 302 2005 143 152
34. N. Machala L. Blaha J. Vondracek J.E. Trosko J. Scott L. Upham Inhibition of gap junctional intercellular communication by noncoplanar polychlorinated biphenyls: inhibitory potencies and screening for potential mode(s) of action Toxicol Sci 76 2003 102 111
35. R. Ricciarelli A. Tasinato S. Clement N.K. Ozer D. Boscoboinik A. Azzi alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state Biochem J 334 1998 243 249
36. O.S. Bang J.H. Park S.S. Kang Activation of PKC but not of ERK is required for vitamin E-succinate-induced apoptosis of HL-60 cells Biochem Biophys Res Commun 288 2001 789 797
37. S.S. Chan H.P. Monteiro F. Schindler A. Stern V.B.C. Junqueira alpha-Tocopherol modulates tyrosine phosphorylation in human neutrophils by inhibition of protein kinase C activity and activation of tyrosine phosphatases Free Radic Res 35 2001 843 856
38. J.C. Herve D. Sarrouilhe Modulation of junctional communication by phosphorylation: protein phosphatases, the missing link in the chain Biol Cell 94 2002 423 432
39. J.L. Solan P.D. Lampe Connexin phosphorylation as a regulatory event linked to gap junction channel assembly Biochim Biophys Acta 1711 2005 154 163
40. K.N. Prasad J.E. Prasad Effects of tocopherol (vitamin E) acid succinate on morphological alterations and growth inhibition in melanoma cells in culture Cancer Res 42 1982 550 555
41. B. Kumar M.N. Jha W.C. Cole J.S. Bedford K.N. Prasad d -alpha-tocopheryl succinate (vitamin E) enhances radiation-induced chromosomal damage levels in human cancer cells, but reduces it in normal cells J Am Coll Nutr 21 2002 339 343
42. M.W. Fariss M.B. Fortuna C.K. Everett J.D. Smith D.F. Trent Z. Djuric The selective antiproliferative effects of alpha-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds Cancer Res 54 1994 3346 3351
43. W.P. Yu B.G. Sanders K. Kline RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria Cancer Res 63 2003 2483 2491
44. H.H. You W.P. Yu B.G. Sanders K. Kline RRR-alpha-tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation Cell Growth Differ 12 2001 471 480
45. A.T. Rose D.W. McFadden Alpha-tocopherol succinate inhibits growth of gastric cancer cells in vitro J Surg Res 95 2001 9 22
46. J. Ni M. Chen Y. Zhang R.S. Li J.T. Huang S.Y. Yeh Vitamin E succinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery Biochem Biophys Res Commun 300 2003 357 363
47. M.P. Malafa F.D. Fokum A. Mowlavi M. Abusief M. King Vitamin E inhibits melanoma growth in mice Surgery 131 2002 85 91
48. E. Cho D.J. Hunter D. Spiegelman D. Albanes W.L. Beeson P.A. van den Brandt Intakes of vitamins A, C and E and folate and multivitamins and lung cancer: a pooled analysis of 8 prospective studies Int J Cancer 118 2006 970 978
49. D. Albanes O.P. Heinonen P.R. Taylor J. Virtamo B.K. Edwards M. Rautalahti Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: effects of base-line characteristics and study compliance J Natl Cancer Inst 88 1996 1560 1570
50. E.R. Miller R. Pastor-Barriuso D. Dalal R.A. Riemersma L.J. Appel E. Guallar Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality Ann Intern Med 142 2005 37 46