Imaging Techniques for Adrenal Lesion Characterization

Radiologic Clinics of North America

Volumn 46, Issue 1, 2008, Pages 65-78

  Blake, Michael A ^a,b   Holalkere, Nagaraj Setty ^a,b   Boland, Giles W ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOMA; ADRENAL BIOPSY; ADRENAL CYST; ADRENAL IMAGING TECHNIQUE; ADRENAL INCIDENTALOMA; ADRENAL LESION; ASPIRATION BIOPSY; ATTENUATION; BIOCHEMISTRY; BLEEDING; CHARACTER; CLINICAL ASSESSMENT; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CORTICAL ADENOMA; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; GANGLIONEUROMA; GRANULOMATOSIS; HEMANGIOMA; INJURY; LIPID SENSITIVE IMAGING TECHNIQUE; MORPHOLOGY; MYELOLIPOMA; NEUROBLASTOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PERCUTANEOUS NEEDLE ASPIRATION BIOPSY; PHEOCHROMOCYTOMA; POSITRON EMISSION TOMOGRAPHY; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; REVIEW; SENSITIVITY AND SPECIFICITY; TECHNIQUE;

ADRENAL GLAND DISEASES; BIOPSY; CONTRAST MEDIA; DIAGNOSTIC IMAGING; HUMANS; MAGNETIC RESONANCE IMAGING; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, X-RAY COMPUTED;

EID: 40049103887     PISSN: 00338389     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rcl.2008.01.003     Document Type: Review

References (76)

1. Young Jr. W.F. The incidentally discovered adrenal mass. N Engl J Med 356 (2007) 601-610
2. Bovio S., Cataldi A., Reimondo G., et al. Prevalence of adrenal incidentaloma in a contemporary computerized tomography series. J Endocrinol Invest 29 (2006) 298-302
3. Mansmann G., Lau J., Blak E., et al. The clinically inapparent adrenal mass. Update in diagnosis and treatment. Endocr Rev 25 2 (2004) 309-340
4. Dunnick N.R., and Korobkin M. Imaging of adrenal incidentalmomas. AJR Am J Roentgenol 179 (2002) 559-568
5. Korobkin M. CT characterization of adrenal masses: the time has come. Radiology 217 (2000) 629-632
6. Kloos R.T., Gross M.D., Francis I.R., et al. Incidentally discovered adrenal masses. Endocr Rev 16 (1995) 460-484
7. Young Jr. W.F. Management approaches to adrenal incidentalomas: a view from Rochester, Minnesota. Endocrinol Metab Clin North Am 29 (2000) 159-185
8. Barzon L., Sonino N., Fallo F., et al. Prevalence and natural history of adrenal incidentalomas. Eur J Endocrinol 149 (2003) 273-285
9. Song J.H., Chaudhry F.S., and Mayo-Smith W.W. The incidental indeterminate adrenal mass on CT (>10HU) in patients without cancer. Is further imaging necessary? Follow-up of 321 consecutive indeterminate adrenal masses. AJR Am J Roentgenol 189 (2007) 1119-1123
10. Slattery J.M., Blake M.A., Kalra M.K., et al. Adrenocortical carcinoma: contrast washout characteristics on CT. AJR Am J Roentgenol 187 (2006) W21-W24
11. Angeli A., Osella G., Ali A., et al. Adrenal incidentaloma: an overview of clinical and epidemiological data from the National Italian Study Group. Horm Res 47 (1997) 279-283
12. Abrams H.L., Spiro R., and Goldstein N. Metastases in carcinoma: analysis of 1000 autopsied cases. Cancer 3 (1950) 74-85
13. Boland G.W., Lee M.J., Gazelle G.S., et al. Characterization of adrenal masses using unenhanced CT: an analysis of the CT literature. AJR Am J Roentgenol 171 (1998) 201-204
14. Russell C., Goodacre B.W., vanSonnenberg E., et al. Spontaneous rupture of adrenal myelolipoma: spiral CT appearance. Abdom Imaging 25 (2000) 431-434
15. Blake M.A., Kalra M.K., Maher M.M., et al. Pheochromocytoma: an imaging chameleon. Radiographics 24 (2004) S87-S89
16. Szolar D.H., Melvyn Korobkin M., Reittner P., et al. Adrenocortical carcinomas and adrenal pheochromocytomas: mass and enhancement loss evaluation at delayed contrast-enhanced CT. Radiology 234 (2005) 479-485
17. Rozenblit A., Morehouse H.T., and Amis Jr. S.E. Cystic adrenal lesions: CT features. Radiology 201 (1996) 541-548
18. Benitah N., Yeh B.M., and Qayyum A. Minor morphologic abnormalities of adrenal glands at CT: prognostic importance in patients with lung cancer. Radiology 235 (2005) 517-522
19. Korobkin M., Giordano T.J., Brodeur F.J., et al. Adrenal adenomas: relationship between histologic lipid and CT and MR findings. Radiology 200 (1996) 743-747
20. Anderson J.B., and Gray G.F. Adrenal pathology. In: Vaughan E.D., and Carey R.M. (Eds). Adrenal disorders (1989), Thieme Medical, New York 18-19
21. Carney J.A. Adrenal gland. In: Sternberg S.S. (Ed). Histology for pathologists (1992), Raven, New York 150-154
22. Lee M.J., Hahn P.F., Papanicolau N., et al. Benign and malignant adrenal masses: CT distinction with attenuation coefficients, size, and observer analysis. Radiology 179 (1991) 415-418
23. Caoili E.M., Korobkin M., Francis I.R., et al. Adrenal masses: characterization with combined unenhanced and delayed enhanced CT. Radiology 222 (2002) 629-633
24. Boland G.W., Hahn P.F., Pena C., et al. Adrenal masses: characterization with delayed contrast-enhanced CT. Radiology 202 (1997) 693-696
25. Korobkin M., Brodeur F.J., Yutzy G.G., et al. Differentiation of adrenal adenomas from nonadenomas using CT attenuation values. AJR Am J Roentgenol 166 (1996) 531-536
26. Korobkin M., Brodeur F.J., Francis I.R., et al. CT time-attenuation washout curves of adrenal adenomas and nonadenomas. AJR Am J Roentgenol 170 (1998) 747-752
27. Szolar D.H., and Kammerhuber F.H. Adrenal adenomas and nonadenomas: assessment of washout at delayed contrast-enhanced CT. Radiology 207 (1998) 369-375
28. Pena C.S., Boland G.W., Hahn P.F., et al. Characterization of indeterminate (lipid-poor) adrenal masses: use of washout characteristics at contrast-enhanced CT. Radiology 217 (2000) 798-802
29. Caoili E.M., Korobkin M., Francis I.R., et al. Delayed enhanced CT of lipid-poor adrenal adenomas. AJR Am J Roentgenol 175 (2000) 1411-1415
30. Bae K.T., Fuangtharnthip P., Prasad S.R., et al. Adrenal masses: CT characterization with histogram analysis method. Radiology 228 (2003) 735-742
31. Jhaveri K.S., Wong F., Ghai S., et al. Comparison of CT histogram analysis and chemical shift MRI in the characterization of indeterminate adrenal nodules. Am J Roentgenol 187 (2006) 1303-1308
32. Remer E.M., Motta-Ramirez G.A., Shepardson L.B., et al. CT histogram analysis in pathologically proven adrenal masses. Am J Roentgenol 187 (2006) 191-196
33. Wang B., Gao Z., Zou Q., et al. Quantitative diagnosis of fatty liver with dual-energy CT. An experimental study in rabbits. Acta Radiol 44 1 (2003) 92-97
34. Raptopoulos V., Karellas A., Bernstein J., et al. Value of dual-energy CT in differentiating focal fatty infiltration of the liver from low-density masses. AJR Am J Roentgenol 157 4 (1991) 721-725
35. Li J., Kalra M.K., and Small W.C. Adrenal mass: differentiation by attenuation characteristics using dual-energy MDCT. Am J Roentgenol 188 Suppl 5 (2007) A59-A62
36. Korobkin M., Lombardi T.J., Aisen A.M., et al. Characterization of adrenal masses with chemical shift and gadolinium-enhanced MR imaging. Radiology 197 (1995) 411-418
37. Outwater E.K., Siegelman E.S., Huang A.B., et al. Adrenal masses: correlation between CT attenuation value and chemical shift ratio at MR imaging with in-phase and opposed-phase sequences. Radiology 200 (1996) 749-752
38. Fujiyoshi F., Nakajo M., Kukukura Y., et al. Characterization of adrenal tumors by chemical shift fast-low angle shot MR imaging: comparison of four methods of quantitative evaluation. Am J Roentgenol 180 (2003) 1649-1657
39. Mayo-Smith W.W., Lee M., McNicholas M.M., et al. Characterization of adrenal masses (<5 cm) by use of chemical shift MR imaging: observer performance versus quantitative measures. Am J Roentgenol 165 (1995) 91-95
40. McNicholas M.M., Lee M.J., Mayo-Smith W.W., et al. An imaging algorithm for the differential diagnosis of adrenal adenomas and metastases. Am J Roentgenol 165 (1995) 1453-1459
41. Israel G.M., Korobkin M., Wang C., et al. Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas. AJR Am J Roentgenol 183 (2004) 215-219
42. Haider M.A., Ghai S., Jhaveri K., et al. Chemical shift MR imaging of hyperattenuating (>10 HU) adrenal masses: does it still have a role?. Radiology 231 (2004) 711-716
43. Park B.K., Kim C.K., Kim B., et al. Comparison of delayed enhanced CT and chemical shift MR for evaluating hyperattenuating incidental adrenal masses. Radiology 243 (2007) 760-765
44. Blake M.A., Slattery J.M., Kalra M.K., et al. Adrenal lesions: characterization with fused PET/CT image in patients with proved or suspected malignancy-initial experience. Radiology 238 (2006) 970-977
45. Blake M.A., Kalra M.K., Sweeney A.T., et al. Distinguishing benign from malignant adrenal masses: multi-detector row CT protocol with 10-minute delay. Radiology 238 (2005) 578-585
46. Luypaert R., Boujraf S., Sourbron S., et al. Diffusion and perfusion MRI: basic physics. Eur J Radiol 38 1 (2001) 19-27
47. Uhl M., Altehoefer C., Kontny U., et al. MRI-diffusion imaging of neuroblastomas: first results and correlation to histology. Eur Radiol 12 9 (2002) 2335-2338
48. Faria J.F., Goldman S.M., Szejnfeld J., et al. Adrenal masses: characterization with in vivo proton MR spectroscopy-initial experience. Radiology 245 (2007) 788-797
49. Sahani D.V., Holalkere N.S., Mueller P.R., et al. Advanced hepatocellular carcinoma: CT perfusion of liver and tumor tissue-initial experience. Radiology 243 3 (2007) 736-743
50. Jain R.K., Munn L.L., and Fukumura D. Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer 2 (2002) 266-276
51. Krestin G.P., Steinbrich W., and Friedmann G. Adrenal masses: evaluation with fast gradient-echo MR imaging and Gd-DTPA-enhanced dynamic studies. Radiology 171 (1989) 675-680
52. Murea S., Mainolfi C., Bazzicalupo I., et al. Imaging of adrenal tumors using FDG-PET: comparison of benign and malignant lesions. AJR Am J Roentgenol 173 (1999) 25-29
53. Boland G.W., Goldberg M.A., Lee M.J., et al. Indeterminate adrenal mass in patients with cancer: evaluation at PET with 2-[F-18]-fluoro-2-deoxy-D-glucose. Radiology 194 (1995) 131-134
54. Erasmus J.J., Patz Jr. E.F., McAdams H.P., et al. Evaluation of adrenal masses in patients with bronchogenic carcinoma using 18F-fluorodeoxyglucose positron emission tomography. AJR Am J Roentgenol 168 (1997) 1357-1360
55. Maurea S., Klain M., Mainolfi C., et al. The diagnostic role of radionuclide imaging in evaluation of patients with nonhypersecreting adrenal masses. J Nucl Med 42 (2001) 884-892
56. Gupta N.C., Graeber G.M., Tamim W.J., et al. Clinical utility of PET-FDG imaging in differentiation of benign from malignant adrenal masses in lung cancer. Clin Lung Cancer 3 (2001) 59-64
57. Rohren E.M., Turkington T.G., and Coleman R.E. Clinical applications of PET in oncology. Radiology 231 (2004) 305-332
58. Elaini A.B., Shetty S.K., Chapman V.M., et al. Improved detection and characterization of adrenal disease with PET-CT. Radiographics 27 (2007) 755-767
59. Metser U., Miller E., Lerman H., et al. 18F-FDG PET/CT in the evaluation of adrenal masses. J Nucl Med 47 (2006) 32-37
60. Rao S.K., Caride V.J., Ponn R., et al. F-18 fluorodeoxyglucose positron emission tomography-positive benign adrenal cortical adenoma: imaging features and pathologic correlation. Clin Nucl Med 29 (2004) 300-302
61. Bagheri B., Maurer A.H., Cone L., et al. Characterization of the normal adrenal gland with 18F-FDG PET/CT. J Nucl Med 45 (2004) 1340-1343
62. Francis I.R., Smid A., Gross M.D., et al. Adrenal masses in oncologic patients: functional and morphologic evaluation. Radiology 166 (1988) 353-356
63. Francis I.R., Glazer G.M., Shapiro B., et al. Complementary roles of CT and 131I-MIBG scintigraphy in diagnosing pheochromocytoma. AJR Am J Roentgenol 141 (1983) 719-725
64. Shulkin B.L., Koeppe R.A., Francis I.R., et al. Pheochromocytomas that do not accumulate metaiodobenzylguanidine: localization with PET and administration of FDG. Radiology 186 (1993) 711-715
65. Shapiro B., Copp J.E., Sisson J.C., et al. Iodine-131 metaiodobenzylguanidine for the locating of suspected pheochromocytoma: experience in 400 cases. J Nucl Med 26 (1985) 576-585
66. Maurea S., Cuocolo A., Reynolds J.C., et al. Iodine-131-metaiodobenzylguanidine scintigraphy in preoperative and postoperative evaluation of paragangliomas: comparison with CT and MRI. J Nucl Med 34 (1993) 173-179
67. Freitas J.E. Adrenal cortical and medullary imaging. Semin Nucl Med 25 (1995) 235-250
68. Chong S., Lee K.S., and Kim A.H. Intergrated PET-CT for the characterization of adrenal lesions in cancer patients: diagnostic efficacy and interpretation pitfalls. Radiographics 26 (2006) 1811-1826
69. Yun M., Kim W., Alnafisi N., et al. 18F-FDG PET in characterizing adrenal lesions detected on CT or MRI. J Nucl Med 42 (2001) 1795-1799
70. Shulkin B., Thompson N.W., Shapiro B., et al. Pheochromocytomas: imaging with 2-[fluorine -18]fluoro-2-deoxy-D-glucose PET. Radiology 212 (1999) 35-41
71. Ilias I., Yu J., Carrasquillo J.A., et al. Superiority of 6-[18F]-fluorodopamine positron emission tomography versus [131I] metaiodobenzylguanidine scintigraphy in the localization of metastatic pheochromocytoma. J Clin Endocrinol Metab 88 (2003) 4083-4087
72. Trampal C., Engler H., Juhlin C., et al. Pheochromocytomas: detection with 11C hydroxyephedrine PET. Radiology 230 (2004) 423-428
73. Paulsen S.D., Nghiem H.V., Korobkin M., et al. Changing role of imaging-guided percutaneous biopsy of adrenal masses: evaluation of 50 adrenal biopsies. AJR Am J Roentgenol 182 (2004) 1033-1103
74. Welch T.J., Sheedy II P.F., Stephens D.H., et al. Percutaneous adrenal biopsy: review of a 10-year experience. Radiology 193 (1994) 341-344
75. Silverman S.G., Mueller P.R., Pinkney L.P., et al. Predictive value of image-guided adrenal biopsy: analysis of results of 101 biopsies. Radiology 187 (1993) 715-718
76. Blake M.A., Sweeney A.T., Kalra M.K., et al. Collision adrenal tumors on PET/CT. Am J Roentgenol 183 3 (2004) 864-865