Analysis of cell-cycle-dependent production of tissue plasminogen activator analogue (pamiteplase) by CHO cells

Biochemical Engineering Journal

Volumn 39, Issue 2, 2008, Pages 297-304

  Yokota, Masami ^a,b   Tanji, Yasunori ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Cell cycle; Cell cycle time; CHO; Mitosis; Modelling; Recombinant protein production; Specific production rate; t PA

Indexed keywords

CELL CULTURE; CELL GROWTH; CLONING; GROWTH RATE; PROTEINS;

CELL CYCLE TIME; MITOSIS; RECOMBINANT PROTEIN PRODUCTION; SPECIFIC PRODUCTION RATE;

ENZYME ACTIVITY;

PAMITEPLASE; TISSUE PLASMINOGEN ACTIVATOR DERIVATIVE;

ARTICLE; CELL CULTURE; CELL CYCLE; CELL CYCLE S PHASE; CELL GROWTH; CELL SYNCHRONIZATION; CHO CELL; LINEAR REGRESSION ANALYSIS; MITOSIS; MITOSIS RATE; PRIORITY JOURNAL;

EID: 40049102950     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2007.09.016     Document Type: Article

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