메뉴 건너뛰기




Volumn 21, Issue 2, 2008, Pages 324-330

Regulation of peroxisome proliferator-activated receptor-α expression during lung inflammation

Author keywords

Acute lung injury; Asthma; Dexamethasone; Fenofibrate; Inflammation; Lipopolysaccharide; Lung; Mouse; PPAR ; Tumor necrosis factor

Indexed keywords

DEXAMETHASONE; FENOFIBRATE; GLUCOCORTICOID; LIPOPOLYSACCHARIDE; MESSENGER RNA; OVALBUMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 40049100693     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2007.08.001     Document Type: Article
Times cited : (37)

References (26)
  • 1
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: nuclear control of metabolism
    • Desvergne B., and Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20 (1999) 649-688
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 4
    • 0035866756 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats
    • Tanaka T., Kohno H., Yoshitani S., Takashima S., Okumura A., Murakami A., et al. Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats. Cancer Res 61 (2001) 2424-2428
    • (2001) Cancer Res , vol.61 , pp. 2424-2428
    • Tanaka, T.1    Kohno, H.2    Yoshitani, S.3    Takashima, S.4    Okumura, A.5    Murakami, A.6
  • 5
    • 2242436246 scopus 로고    scopus 로고
    • Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice
    • Duez H., Chao Y.S., Hernandez M., Torpier G., Poulain P., Mundt S., et al. Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice. J Biol Chem 277 (2002) 48051-48057
    • (2002) J Biol Chem , vol.277 , pp. 48051-48057
    • Duez, H.1    Chao, Y.S.2    Hernandez, M.3    Torpier, G.4    Poulain, P.5    Mundt, S.6
  • 6
    • 0036153739 scopus 로고    scopus 로고
    • Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models
    • Sheu M.Y., Fowler A.J., Kao J., Schmuth M., Schoonjans K., Auwerx J., et al. Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. J Invest Dermatol 118 (2002) 94-101
    • (2002) J Invest Dermatol , vol.118 , pp. 94-101
    • Sheu, M.Y.1    Fowler, A.J.2    Kao, J.3    Schmuth, M.4    Schoonjans, K.5    Auwerx, J.6
  • 7
    • 20444440328 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB signaling by fenofibrate, a peroxisome proliferator-activated receptor-alpha ligand, presents a therapeutic strategy for rheumatoid arthritis
    • Okamoto H., Iwamoto T., Kotake S., Momohara S., Yamanaka H., and Kamatani N. Inhibition of NF-kappaB signaling by fenofibrate, a peroxisome proliferator-activated receptor-alpha ligand, presents a therapeutic strategy for rheumatoid arthritis. Clin Exp Rheumatol 23 (2005) 323-330
    • (2005) Clin Exp Rheumatol , vol.23 , pp. 323-330
    • Okamoto, H.1    Iwamoto, T.2    Kotake, S.3    Momohara, S.4    Yamanaka, H.5    Kamatani, N.6
  • 8
    • 0031813989 scopus 로고    scopus 로고
    • Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIb
    • Madej A., Okopien B., Kowalski J., Zielinski M., Wysocki J., Szygula B., et al. Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIb. Int J Clin Pharmacol Ther 36 (1998) 345-349
    • (1998) Int J Clin Pharmacol Ther , vol.36 , pp. 345-349
    • Madej, A.1    Okopien, B.2    Kowalski, J.3    Zielinski, M.4    Wysocki, J.5    Szygula, B.6
  • 9
    • 0032565868 scopus 로고    scopus 로고
    • Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators
    • Staels B., Koenig W., Habib A., Merval R., Lebret M., Torra I.P., et al. Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators. Nature 393 (1998) 790-793
    • (1998) Nature , vol.393 , pp. 790-793
    • Staels, B.1    Koenig, W.2    Habib, A.3    Merval, R.4    Lebret, M.5    Torra, I.P.6
  • 10
    • 0141928029 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: molecular and cellular mechanisms
    • Barnes P.J., Shapiro S.D., and Pauwels R.A. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 22 (2003) 672-688
    • (2003) Eur Respir J , vol.22 , pp. 672-688
    • Barnes, P.J.1    Shapiro, S.D.2    Pauwels, R.A.3
  • 11
    • 4344562943 scopus 로고    scopus 로고
    • New anti-inflammatory therapies and targets for asthma and chronic obstructive pulmonary disease
    • Belvisi M.G., Hele D.J., and Birrell M.A. New anti-inflammatory therapies and targets for asthma and chronic obstructive pulmonary disease. Expert Opin Ther Targets 8 (2004) 265-285
    • (2004) Expert Opin Ther Targets , vol.8 , pp. 265-285
    • Belvisi, M.G.1    Hele, D.J.2    Birrell, M.A.3
  • 12
    • 26244460587 scopus 로고    scopus 로고
    • PPARalpha downregulates airway inflammation induced by lipopolysaccharide in the mouse
    • Delayre-Orthez C., Becker J., Guenon I., Lagente V., Auwerx J., Frossard N., et al. PPARalpha downregulates airway inflammation induced by lipopolysaccharide in the mouse. Respir Res 6 (2005) 91-101
    • (2005) Respir Res , vol.6 , pp. 91-101
    • Delayre-Orthez, C.1    Becker, J.2    Guenon, I.3    Lagente, V.4    Auwerx, J.5    Frossard, N.6
  • 13
    • 0037716526 scopus 로고    scopus 로고
    • PPAR-alpha and -gamma but not -delta agonists inhibit airway inflammation in a murine model of asthma: in vitro evidence for an NF- kappaB-independent effect
    • Trifilieff A., Bench A., Hanley M., Bayley D., Campbell E., and Whittaker P. PPAR-alpha and -gamma but not -delta agonists inhibit airway inflammation in a murine model of asthma: in vitro evidence for an NF- kappaB-independent effect. Br J Pharmacol 139 (2003) 163-171
    • (2003) Br J Pharmacol , vol.139 , pp. 163-171
    • Trifilieff, A.1    Bench, A.2    Hanley, M.3    Bayley, D.4    Campbell, E.5    Whittaker, P.6
  • 15
    • 33748701308 scopus 로고    scopus 로고
    • Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases?
    • Becker J., Delayre-Orthez C., Frossard N., and Pons F. Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases?. Fundam Clin Pharmacol 20 (2006) 429-447
    • (2006) Fundam Clin Pharmacol , vol.20 , pp. 429-447
    • Becker, J.1    Delayre-Orthez, C.2    Frossard, N.3    Pons, F.4
  • 16
    • 0028003839 scopus 로고
    • Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids
    • Lemberger T., Staels B., Saladin R., Desvergne B., Auwerx J., and Wahli W. Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids. J Biol Chem 269 (1994) 24527-24530
    • (1994) J Biol Chem , vol.269 , pp. 24527-24530
    • Lemberger, T.1    Staels, B.2    Saladin, R.3    Desvergne, B.4    Auwerx, J.5    Wahli, W.6
  • 17
    • 0030060358 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm
    • Lemberger T., Saladin R., Vazquez M., Assimacopoulos F., Staels B., Desvergne B., et al. Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm. J Biol Chem 271 (1996) 1764-1769
    • (1996) J Biol Chem , vol.271 , pp. 1764-1769
    • Lemberger, T.1    Saladin, R.2    Vazquez, M.3    Assimacopoulos, F.4    Staels, B.5    Desvergne, B.6
  • 18
    • 0343471402 scopus 로고    scopus 로고
    • TNF-alpha downregulates the peroxisome proliferator activated receptor-alpha and the mRNAs encoding peroxisomal proteins in rat liver
    • Beier K., Volkl A., and Fahimi H.D. TNF-alpha downregulates the peroxisome proliferator activated receptor-alpha and the mRNAs encoding peroxisomal proteins in rat liver. FEBS Lett 412 (1997) 385-387
    • (1997) FEBS Lett , vol.412 , pp. 385-387
    • Beier, K.1    Volkl, A.2    Fahimi, H.D.3
  • 19
    • 0030827807 scopus 로고    scopus 로고
    • Regulation of CYP4A1 and peroxisome proliferator-activated receptor alpha expression by interleukin-1beta, interleukin-6, and dexamethasone in cultured fetal rat hepatocytes
    • Parmentier J.H., Schohn H., Bronner M., Ferrari L., Batt A.M., Dauca M., et al. Regulation of CYP4A1 and peroxisome proliferator-activated receptor alpha expression by interleukin-1beta, interleukin-6, and dexamethasone in cultured fetal rat hepatocytes. Biochem Pharmacol 54 (1997) 889-898
    • (1997) Biochem Pharmacol , vol.54 , pp. 889-898
    • Parmentier, J.H.1    Schohn, H.2    Bronner, M.3    Ferrari, L.4    Batt, A.M.5    Dauca, M.6
  • 20
    • 0037523216 scopus 로고    scopus 로고
    • Hepatic expression of PPARalpha, a molecular target of fibrates, is regulated during inflammation in a gender-specific manner
    • Tai E.S., bin Ali A., Zhang Q., Loh L.M., Tan C.E., Retnam L., et al. Hepatic expression of PPARalpha, a molecular target of fibrates, is regulated during inflammation in a gender-specific manner. FEBS Lett 546 (2003) 237-240
    • (2003) FEBS Lett , vol.546 , pp. 237-240
    • Tai, E.S.1    bin Ali, A.2    Zhang, Q.3    Loh, L.M.4    Tan, C.E.5    Retnam, L.6
  • 21
    • 9244245182 scopus 로고    scopus 로고
    • Dose-dependent effects of endotoxins on allergen sensitization and challenge in the mouse
    • Delayre-Orthez C., de Blay F., Frossard N., and Pons F. Dose-dependent effects of endotoxins on allergen sensitization and challenge in the mouse. Clin Exp Allergy 34 (2004) 1789-1795
    • (2004) Clin Exp Allergy , vol.34 , pp. 1789-1795
    • Delayre-Orthez, C.1    de Blay, F.2    Frossard, N.3    Pons, F.4
  • 22
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • Braissant O., Foufelle F., Scotto C., Dauca M., and Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137 (1996) 354-366
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 23
    • 0031952238 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor-alpha expression in human liver
    • Palmer C.N., Hsu M.H., Griffin K.J., Raucy J.L., and Johnson E.F. Peroxisome proliferator activated receptor-alpha expression in human liver. Mol Pharmacol 53 (1998) 14-22
    • (1998) Mol Pharmacol , vol.53 , pp. 14-22
    • Palmer, C.N.1    Hsu, M.H.2    Griffin, K.J.3    Raucy, J.L.4    Johnson, E.F.5
  • 24
    • 0034801882 scopus 로고    scopus 로고
    • Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding
    • Escher P., Braissant O., Basu-Modak S., Michalik L., Wahli W., and Desvergne B. Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding. Endocrinology 142 (2001) 4195-4202
    • (2001) Endocrinology , vol.142 , pp. 4195-4202
    • Escher, P.1    Braissant, O.2    Basu-Modak, S.3    Michalik, L.4    Wahli, W.5    Desvergne, B.6
  • 25
    • 33748502269 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes
    • Reynders V., Loitsch S., Steinhauer C., Wagner T., Steinhilber D., and Bargon J. Peroxisome proliferator-activated receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes. Respir Res 7 (2006) 104-118
    • (2006) Respir Res , vol.7 , pp. 104-118
    • Reynders, V.1    Loitsch, S.2    Steinhauer, C.3    Wagner, T.4    Steinhilber, D.5    Bargon, J.6
  • 26
    • 40049086717 scopus 로고    scopus 로고
    • Remels AH, Schrauwen P, Broekhuizen R, Willems J, Kersten S, Gosker HR, et al. Expression and content of PPARs is reduced in skeletal muscle of COPD patients. Eur Respir J 2007.
    • Remels AH, Schrauwen P, Broekhuizen R, Willems J, Kersten S, Gosker HR, et al. Expression and content of PPARs is reduced in skeletal muscle of COPD patients. Eur Respir J 2007.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.