Insight into the bioreductive mode of action of antitrypanosomal 5-nitrofuryl containing thiosemicarbazones

Medicinal Chemistry

Volumn 4, Issue 1, 2008, Pages 11-17

  Otero, L ^a   Maya, J D ^b   Morello, A ^b   Rigol, C ^c   Barriga, G ^c,d   Rodriguez J ^c,d   Folch, C ^c,d   Norambuena, E ^d   Gonzalez M ^e   Olea Azar, C ^c   Cerecetto, H ^e   Gambino, D ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF CHILE   (Chile)

^d UNIVERSIDAD METROPOLITANA DE CIENCIAS DE LA EDUCACIÓN   (Chile)

^e UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

5 nitrofuryl containing thiosemicarbazones; Chagas disease; ESR; ORAC

Indexed keywords

ACROLEIN DERIVATIVE; ANTITRYPANOSOMAL AGENT; FREE RADICAL; FURFURAL; FURYLACROLEINE DERIVATIVE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; ELECTRON SPIN RESONANCE; IN VITRO STUDY; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SCAVENGING SYSTEM; SIGNAL PROCESSING; SPIN TRAPPING; TRYPANOSOMA CRUZI;

EID: 40049096165     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340608783331470     Document Type: Article

References (36)