Tektin5, a new TEKTIN family member, is a component of the middle piece of flagella in rat spermatozoa

Molecular Reproduction and Development

Volumn 75, Issue 4, 2008, Pages 650-658

  Murayama, Emi ^a   Yamamoto, Etsuko ^a   Kaneko, Takane ^a   Shibata, Yosaburo ^b   Inai, Tetsuichiro ^b   Iida, Hiroshi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Axoneme; Flagellum; Sperm; Tektin; Testis

Indexed keywords

MICROTUBULE PROTEIN; PROTEIN TEKTIN 5; UNCLASSIFIED DRUG;

ANTIBODY LABELING; ARTICLE; CONFOCAL LASER MICROSCOPY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPERMATOZOON; SPERMATOZOON MOTILITY; TESTIS DEVELOPMENT; UPREGULATION;

MAMMALIA; RATTUS;

EID: 40049093698     PISSN: 1040452X     EISSN: 10982795     Source Type: Journal    
DOI: 10.1002/mrd.20804     Document Type: Article

References (27)

1. Cao W, Gerton GL, Moss SB. 2006. Proteomic profiling of accessory structures from the mouse sperm flagellum. Mol Cell Proteomics 5: 801–810.
2. Doiguchi M, Yamashita H, Ichinose J, Mori T, Shibata Y, Iida H. 2002a. Complementary DNA cloning and characterization of rat spergen‐1, a spermatogenic cell‐specific gene‐1, containing a mitochondria‐targeting signal. Biol Reprod 66: 1462–1470.
3. Doiguchi M, Mori T, Toshimori K, Shibata Y, Iida H. 2002b. Spergen‐1 might be an adhesive molecule associated with mitochondria in the middle piece of spermatozoa. Dev Biol 252: 127–137.
4. Gibbons IR. 1981. Cilia and flagella of eukaryotes. J Cell Biol 91: 107–124.
5. Iguchi N, Tanaka H, Fujii T, Tamura K, Kaneko Y, Nojima H, Nishimune Y. 1999. Molecular cloning of haploid germ cell‐specific tektin cDNA and analysis of the protein in mouse testis. FEBS Lett 456: 315–321.
6. Iguchi N, Tanaka H, Nakamura Y, Nozaki M, Fujiwara T, Nishimune Y. 2002. Cloning and characterization of the human tektin‐t gene. Mol Hum Reprod 8: 525–530.
7. Iida H, Yoshinaga Y, Tanaka S, Toshimori K, Mori T. 1999. Identification of rab 3A GTPase as an acrosome‐associated small GTP binding protein in rat sperm. Dev Biol 211: 144–155.
8. Iida H, Ichinose J, Kaneko T, Mori T, Shibata Y. 2004. Complementary DNA cloning of rat Spetex‐1, a spermatid‐expressing gene‐1, encoding a 63 kDa cytoplasmic protein of elongate spermatids. Mol Reprod Dev 68: 385–393.
9. Iida H, Honda Y, Matsuyama T, Shibata Y, Inai T. 2006a. Spetex‐1: A new component in the middle piece of flagellum in rodent spermatozoa. Mol Reprod Dev 73: 342–349.
10. Iida H, Honda Y, Matsuyama T, Shibata Y, Inai T. 2006b. Tektin 4 is located on outer dense fibers, not associated with axonemal tubulins of flagella in rodent spermatozoa. Mol Reprod Dev 73: 929–936.
11. Katafuchi K, Mori T, Toshimori K, Iida H. 2000. Localization of a syntaxin isoform, syntaxin 2, to the acrosomal region of rodent spermatozoa. Mol Reprod Dev 57: 375–383.
12. Larsson M, Norrander J, Graslund S, Brundell E, Linck R, Stahl S, Hoog C. 2000. The spatial and temporal expression of Tekt1, a mouse tektin C homologue, during spermatogenesis suggests that it is involved in the development of the sperm tail basal body and axoneme. Eur J Cell Biol 79: 718–725.
13. Linck RW, Albertini DF, Kenney DM, Langevin GL. 1982. Tektin filaments: Chemically unique filaments of sperm flagellar microtubules. Prog Clin Biol Res 80: 127–132.
14. Matsuyama T, Honda Y, Doiguchi M, Iida H. 2005. Molecular cloning of a new member of TEKTIN family, tektin4, located to the flagella of rat spermatozoa. Mol Reprod Dev 72: 120–128.
15. Mohri H. 1993. Role of tubulin and dynein in spermatozoan motility. Mol Reprod Dev 36: 221–222.
16. Nojima D, Linck RW, Egelman EH. 1995. At least one of the protofilaments in flagellar microtubules is not composed of tubulin. Curr Biol 5: 158–167.
17. Norrander JM, Perrone CA, Amos LA, Linck RW. 1996. Structural comparison of tektins and evidence for their determination of complex spacings in flagellar microtubules. J Mol Biol 257: 385–397.
18. Norrander J, Larsson M, Stahl S, Hoog C, Linck R. 1998. Expression of ciliary tektins in brain and sensory development. J Neurosci 18: 8912–8918.
19. Olmsted JB. 1986. Microtubule‐associated protein. Annu Rev Cell Biol 2: 421–457.
20. Ota A, Kusakabe T, Sugimoto Y, Takahashi M, Nakajima Y, Kawaguchi Y, Koga K. 2002. Cloning and characterization of testis‐specific tektin in Bombyx mori. Comp Biochem Physiol B 133: 371–382.
21. Roy A, Yan W, Burns KH, Matzuk MM. 2004. Tektin3 encodes an evolutionarily conserved putative testicular microtubules‐related protein expressed preferentially in male germ cells. Mol Reprod Dev 67: 295–302.
22. Roy A, Lin YN, Agno JE, Demayo FJ, Matzuk MM. 2007. Absence of tektin 4 causes asthenozoospermia and subfertility in male mice. FASEB J 21: 1013–1025.
23. Steffen W, Linck RW. 1988. Evidence for tektins in centrioles and axonemal doublet microtubules. Proc Natl Acad Sci USA 85: 2643–2647.
24. Sullivan KF. 1998. Structure and utilization of tubulin isotype. Annu Rev Cell Biol 4: 687–716.
25. Tanaka H, Iguchi N, Toyama Y, Kitamura K, Takahashi T, Kaseda K, Maekawa M, Nishimune Y. 2004. Mice deficient in the axonemal protein Tektin‐t exhibit male infertility and immotile‐cilium syndrome due to impaired inner arm dynein function. Mol Cell Biol 24: 7958–7964.
26. Wolkowicz MJ, Naaby‐Hansen S, Gamble AR, Reddi PP, Flickinger CL, Herr JC. 2002. Tektin B1 demonstrates flagellar localization in human sperm. Biol Reprod 66: 241–250.
27. Xu M, Zhou Z, Cheng C, Zhao W, Tang R, Huang Y, Wang W, Xu J, Zeng L, Xie Y, Mao Y. 2001. Cloning and characterization of a novel human TEKTIN1 gene. Int J Biochem Cell Biol 33: 1172–1182.