Membrane proteins of the endoplasmic reticulum induce high-curvature tubules

Science

Volumn 319, Issue 5867, 2008, Pages 1247-1250

  Hu, Junjie ^a   Shibata, Yoko ^a   Voss, Christiane ^b   Shemesh, Tom ^c   Li, Zongli ^d   Coughlin, Margaret ^d   Kozlov, Michael M ^c   Rapoport, Tom A ^a   Prinz, William A ^b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTOR YAP1;

HYDROPHOBICITY; MEMBRANE; MUTATION; PLASMA; PROTEIN;

ARTICLE; ENDOPLASMIC RETICULUM; IN VITRO STUDY; IN VIVO STUDY; MUTATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PURIFICATION; PROTEOLIPOSOME;

AMINO ACID SEQUENCE; ANIMALS; BIOPOLYMERS; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; HYDROPHOBICITY; INTRACELLULAR MEMBRANES; LIPID BILAYERS; MEMBRANE LIPIDS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICROSCOPY, ELECTRON; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEOLIPIDS; SACCHAROMYCES CEREVISIAE PROTEINS;

MAMMALIA;

EID: 40049085592     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1153634     Document Type: Article

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27. We thank D. Moazed, B. Glick, and R. Yan for materials; T. Walz and T. Mitchison for discussions; D. Kelly and G. Skiniotis for comments; and J. F. Ménétret and M. Ericsson for help with EM experiments. C.V. and W.A.P. were supported by the NIDDK intramural program. T.A.R. is a Howard Hughes Medical Institute Investigator.