Adrenaline attenuates the acute lung injury after intratracheal lipopolysaccharide instillation: An experimental study

Inhalation Toxicology

Volumn 20, Issue 4, 2008, Pages 445-453

  Philippakis, G E ^a   Lazaris, A C ^b   Papathomas, T G ^b,d   Zissis, C ^a   Agrogiannis, G ^b   Thomopoulou, G ^b   Nonni, A ^b   Xiromeritis, K ^b   Nikolopoulou Stamati, P ^b   Bramis, J ^b   Patsouris, E ^b   Perrea, D ^c   Bellenis, I ^a  

^a EVANGELISMOS HOSPITAL   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c UNIVERSITY OF ATHENS   (Greece)

^d NONE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; EXPERIMENTAL STUDY; HELPER CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; INFLAMMATORY INFILTRATE; MACROPHAGE; MALE; MONONUCLEAR CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; SYSTEMIC THERAPY; T LYMPHOCYTE SUBPOPULATION; TREATMENT OUTCOME; UPREGULATION;

ACUTE DISEASE; ANIMALS; BRONCHODILATOR AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELL COUNT; DISEASE MODELS, ANIMAL; DRUG ANTAGONISM; DRUG THERAPY, COMBINATION; EPINEPHRINE; INTERCELLULAR ADHESION MOLECULE-1; INTUBATION, INTRATRACHEAL; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MALE; PNEUMONIA; RATS; UP-REGULATION;

ANIMALIA; NEGIBACTERIA;

EID: 39849107743     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.1080/08958370801903891     Document Type: Article

References (34)

1. Basu, S., and Fenton, M. J. 2004. Toll-like receptors: Function and roles in lung disease. Am. J. Physiol. Lung Cell. Mol. Physiol. 286:887-892.
2. Coimbra, R., Melbostad, H., Loomis, W., Porcides, R. D., Wolf, P., Tobar, M., and Hoyt, D. B. 2006. LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression. J. Trauma 60:115-125.
3. D'Souza, N. B., Mandujano, F. J., Nelson, S., Summer, W. R., and Shellito, J. E. 1994. CD4+ T lymphocyte depletion attenuates lipopolysaccharide-induced tumor necrosis factor secretion by alveolar macrophages in the mouse. Lymphokine Cytokine Res. 13:359-366.
4. Farmer, P., and Pugin, J. 2000. Beta-adrenergic agonists exert their "anti-inflammatory" effects in monocytic cells through the IkappaB/NF-kappaB pathway. Am. J. Physiol. Lung Cell. Mol. Physiol. 279: 675-682.
5. Feng, W. G., Wang, Y. B., Zhang, J. S., Wang, X. Y., Li, C. L., and Chang, Z. L. 2002. cAMP elevators inhibit LPS-induced IL-12 p40 expression by interfering with phosphorylation of p38 MAPK in murine peritoneal macrophages. Cell Res. 12:331-337.
6. Gonzalez, A., Lenzi, H. L., Motta, E. M., Caputo, L., Sahaza, J. H., Cock, A. M., Ruiz, A. C., Restrepo, A., and Cano, L. E. 2005. Expression of adhesion molecules in lungs of mice infected with Paracoccidioides brasiliensis conidia. Microbes Infect. 7:666-673.
7. Hirano, S. 1997. Quantitative time-course profiles of bronchoalveolar lavage cells following intratracheal instillation of lipopolysaccharide in mice. Ind. Health 35:353-358.
8. Ivashkiv, L. B., Ayres, A., and Glimcher, L. H. 1994. Inhibition of IFN-gamma induction of class II MHC genes by cAMP and prostaglandins. Immunopharmacology 27:67-77.
9. Larsson, R., Rocksen, D., Lilliehook, B., Jonsson, A., and Bucht, A. 2000. Dose-dependent activation of lymphocytes in endotoxin-induced airway inflammation. Infect. Immun. 68:6962-6969.
10. Leurs, R., Beusenberg, F. D., Bast, A., Van Amsterdam, J. G., and Timmerman, H. 1990. Identification of beta 2-adrenoceptors on guinea pig alveolar macrophages using (-)-3-[125I]iodocyanopindolol. Inflammation 14:421-426.
11. Li, G., Harton, J. A., Zhu, X., and Ting, J. P. 2001. Downregulation of CIITA function by protein kinase a (PKA)-mediated phosphorylation: Mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic lines. Mol. Cell Biol. 21:4626-4635.
12. Li, X. C., Miyasaka, M., and Issekutz, T. B. 1998. Blood monocyte migration to acute lung inflammation involves both CD11/CD18 and very late activation antigen-4-dependent and independent pathways. J. Immunol. 161:6258-6264.
13. Liggett, S. B. 1989. Beta-adrenoceptor-effector system of the human macrophage U937 cell line. Eur. J. Pharmacol. 163:171-174.
14. Maris, N. A., de Vos, A. F., Dessing, M. C., Spek, C. A., Lutter, R., Jansen, H. M., van der Zee, J. S., Bresser, P., and van der Poll, T. 2005. Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers. Am. J. Respir. Crit. Care Med. 172: 878-884.
15. Maus, U., Huwe, J., Maus, R., Seeger, W., and Lohmeyer, J 2001. Alveolar JE/MCP-1 and endotoxin synergize to provoke lung cytokine upregulation, sequential neutrophil and monocyte influx, and vascular leakage in mice. Am. J. Respir. Crit. Care Med. 164:406-411.
16. Maus, U., Huwe, J., Ermert, L., Ermert, M., Seeger, W., and Lohmeyer, J 2002. Molecular pathways of monocyte emigration into the alveolar air space of intact mice. Am. J. Respir. Crit. Care Med. 165:95-100.
17. Miggin, S. M., and O'Neill, L. A. 2006. Newinsights into the regulation of TLR signaling. J. Leukocyte Biol. 80:220-226.
18. Monastra, G., and Secchi, E. F. 1993. Beta-adrenergic receptors mediate in vivo the adrenaline inhibition of lipopolysaccharide-induced tumor necrosis factor release. Immunol. Lett. 38:127-130.
19. Nakamura, A., Johns, E. J., Imaizumi, A., Yanagawa, Y., and Kohsaka, T. 1999. Modulation of interleukin-6 by beta2-adrenoceptor in endotoxin-stimulated renal macrophage cells. Kidney Int. 56:839-849.
20. Núñez Miguel, R., Wong, J., Westoll, J. F., Brooks, H. J., O'Neill, L. A., Gay, N. J., Bryant, C. E., and Monie, T. P. 2007. A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins. PLoSONE 2: e788
21. O'Grady, N. P., Preas, H. L., Fiuza, C., Tropea, M., Reda, D., Banks, S. M., and Suffredini, A. F. 2001. Local inflammatory responses following bronchial endotoxin instillation in humans. Am. J. Respir. Crit. Care Med. 163:1591-1598.
22. Platzer, C., Meisel, C., Vogt, K., Platzer, M., and Volk, H. D. 1995. Upregulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs. Int. Immunol. 7:517-523.
23. Rosseau, S., Hammerl, P., Maus, U., Walmrath, H. D., Schütte, H., Grimminger, F., Seeger, W., and Lohmeyer, J. 2000a. Phenotypic characterization of alveolar monocyte recruitment in acute respiratory distress syndrome. Am. J. Physiol. Lung Cell. Mol. Physiol. 279:25-35.
24. Rosseau, S., Selhorst, J., Wiechmann, K., Leissner, K., Maus, U., Mayer, K., Grimminger, F., Seeger, W., and Lohmeyer, J. 2000b. Monocyte migration through the alveolar epithelial barrier: Adhesion molecule mechanisms and impact of chemokines. J. Immunol. 164:427-435.
25. Sandström, T., Bjermer, L., and Rylander, R. 1994. Lipopolysaccharide (LPS) inhalation in healthy subjects causes bronchoalveolar neutrophilia, lymphocytosis, and fibronectin increase. Am. J. Ind. Med. 25:103-104.
26. Schottelius, A. J., Mayo, M. W., Sartor, R. B., and Baldwin, A. S., Jr 1999. Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. J. Biol. Chem. 274:31868-31874.
27. Srivastava, M., Jung, S., Wilhelm, J., Fink, L., Bühling, F., Welte, T., Bohle, R. M., Seeger, W., Lohmeyer, J., and Maus, U. A. 2005. The inflammatory versus constitutive trafficking of mononuclear phagocytes into the alveolar space of mice is associated with drastic changes in their gene expression profiles. J. Immunol. 175:1884-18893.
28. Standiford, T. J., Kunkel, S. L., Greenberger, M. J., Laichalk, L. L., and Strieter, R. M 1996. Expression and regulation of chemokines in bacterial pneumonia. J. Leukocyte Biol. 59:24-28.
29. Tan, K. S., Nackley, A. G., Satterfield, K., Maixner, W., Diatchenko, L., and Flood, P. M. 2007. Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms. Cell Signal. 19:251-260.
30. Vaddi, K., and Newton, R. C. 1994. Regulation of monocyte integrin expression by beta-family chemokines. J. Immunol. 153:4721-4732.
31. van der Poll, T., Coyle, S. M., Barbosa, K., Braxton, C. C., and Lowry, S. F. 1996. Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia. J. Clin. Invest. 97:713-719.
32. Vignola, A. M., Bonsignore, G., Siena, L., Melis, M., Chiappara, G., Gagliardo, R., Bousquet, J., Bonsignore, G., and Merendino, A. M. 2000. ICAM-1 and alpha3beta1 expression by bronchial epithelial cells and their in vitro modulation by inflammatory and anti-inflammatory mediators. Allergy 55:931-939.
33. Williams, J. G., and Carriro, C. J. 2000. Acute respiratory distress syndrome. In General thoracic surgery, 5th ed. , eds. T. W. Shields, J. LoCicero, and R. B. Ponn, pp. 841-852. Philadelphia: Lippincott Williams & Wilkins.
34. Ye, R. D. 2000. Beta-adrenergic agonists regulate NF-kappaB activation through multiple mechanisms. Am. J. Physiol. Lung Cell. Mol. Physiol. 279:615-617.