Assessment of robustness for an LC-MS-MS multi-method by response-surface methodology, and its sensitivity

Analytical and Bioanalytical Chemistry

Volumn 390, Issue 5, 2008, Pages 1317-1326

  Müller, Alexander ^a   Flottmann, Dirk ^b   Schulz, Wolfgang ^a   Seitz, Wolfram ^a   Weber, Walter H ^a  

^a Betriebs und Forschungslaboratorium   (Germany)

^b AALEN UNIVERSITY   (Germany)

Author keywords

Central composite design; LC MS MS; Multi method; Response surface methodology; Robustness; Validation

Indexed keywords

ORGANIC COMPOUNDS; SIGNAL TO NOISE RATIO; WATER RESOURCES;

CENTRAL COMPOSITE DESIGN; RESPONSE SURFACE METHODOLOGY (RSM);

SURFACE MEASUREMENT;

EID: 39849106877     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-007-1793-y     Document Type: Article

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