Transfer of isoniazid from circulation to breast milk in lactating women on chronic therapy for tuberculosis

British Journal of Clinical Pharmacology

Volumn 65, Issue 3, 2008, Pages 418-422

  Singh, Neera ^a   Golani, Anil ^a   Patel, Zarine ^a   Maitra, Anurupa ^a  

^a NATIONAL INSTITUTE FOR RESEARCH IN REPRODUCTIVE HEALTH   (India)

Author keywords

HPLC; Isoniazid; Milk to plasma ratio; Tuberculosis

Indexed keywords

ETHAMBUTOL; ISONIAZID; RIFAMPICIN;

ADULT; AREA UNDER THE CURVE; ARTICLE; BREAST FEEDING; BREAST MILK; CIRCULATION; CLINICAL ARTICLE; COMBINATION CHEMOTHERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MILK LEVEL; FEMALE; HUMAN; LACTATION; PRIORITY JOURNAL; SINGLE DRUG DOSE; TUBERCULOSIS;

ADOLESCENT; ADULT; FEMALE; HUMANS; ISONIAZID; LACTATION; MILK, HUMAN; TUBERCULOSIS;

EID: 39849102827     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2007.03061.x     Document Type: Article

References (16)

1. Ito S, Lee A. Drug excretion into breast milk- overview. Adv Drug Deliv Rev 2003 55 : 617 27.
2. Begg EJ, Duffull SB, Hackett LP, Ilett KF. Studying drugs in human milk: time to unify the approach. J Hum Lact 2002 18 : 323 32.
3. Kacew S. Adverse effects of drugs and chemicals in breast milk on the nursing infant. J Clin Pharmacol 1993 33 : 213 21.
4. Patel SB, Toddywalla VS, Betrabet SS, Kulkarni RD, Patel ZM, Mehta AC, Saxena BN. At what 'infant age' can levo-norgetstrel contraceptives be recommended to nursing mothers? Adv Contracept 1994 10 : 249 55.
5. Khilnani GC. Tuberculosis and pregnancy. Indian J Chest Dis Allied Sci 2004 46 : 105 11.
6. Lass A, Bunger P. Studies on the diffusion of isoniazid in the fetal circulation, the amniotic fluid and human milk. Klin Wochenschr 1953 31 : 606 8.
7. Ricci G, Copaitich T. Elimination of orally administered isoniazid in human milk. Rass Clin Ter 1954 53 : 209 14.
8. Berlin CM Lee C. Isoniazid and acetylisoniazid disposition in human milk, saliva and plasma [Abstract]. Fed Proc 1979 38 : 426.
9. Snider DE Powell KE. Should women taking antituberculosis drugs breastfeed? Arch Intern Med 1984 144 : 589 90.
10. O'Brien RJ, Long MW, Cross FS, Lyle MA, Snider DE. Hepatotoxicity from isoniazid and rifampin among children treated for tuberculosis. Pediatrics 1983 72 : 491 9.
11. Yew WW, Leung CC. Antituberculosis drugs and hepatotoxicity. Respirology 2006 11 : 699 707.
12. Toddywalla VS, Patel SB, Betrabet SS, Kulkarni RD, Saxena BN. Can chronic maternal drug therapy alter the nursing infants hepatic drug metabolizing pattern?. J Clin Pharmacol 1995 35 : 1025 9.
13. Sadeg N, Pertat N, Dutertre H, Dumontet M. Rapid, specific and sensitive method for isoniazid determination in serum. J Chromatogr B Biomed Appl 1996 675 : 113 7.
14. Bennett PN. Use of the monographs on drugs. In : Drugs and Human Lactation, 2nd edn, ed Bennett PN. Amsterdam : Elsevier, 1996 67 74.
15. Begg EJ, Atkinson HC, Duffull SB. Prospective evaluation of a model for the prediction of milk : plasma drug concentrations from physicochemical characteristics. Br J Clin Pharmacol 1992 33 : 501 5.
16. Khayat AP, Rey E, Gendrel D, Kervroedan FV, Cremier O, Athis P, Badoual J, Olive G, Pons G. Isoniazid acetylation metabolic ratio during maturation in children. Clin Pharmacol Ther 1997 62 : 377 83.