Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells and rat proliferating endothelial cells

Molecular Therapy

Volumn 16, Issue 3, 2008, Pages 516-524

  Driessen, Wouter H P ^a   Fujii, Nobutaka ^b   Tamamura, Hirokazu ^c   Sullivan, Sean M ^a  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; CHEMOKINE RECEPTOR CXCR4; CYSTEINE; GREEN FLUORESCENT PROTEIN; LIPOPLEX; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID DERIVATIVE; PLASMID DNA; VASCULOTROPIN;

ANIMAL CELL; ARTICLE; CELL BASED GENE THERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPRESSION VECTOR; GENE TRANSFER; GENETIC TRANSFECTION; GLIOMA CELL; IN VITRO STUDY; INCUBATION TIME; LIPOSOMAL GENE DELIVERY SYSTEM; MESENTERIC ARTERY; NONHUMAN; ORGAN CULTURE; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; REPORTER GENE;

RATTUS;

EID: 39849099655     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300388     Document Type: Article

References (43)

1. NS Templeton DD Lasic PM Frederik HH Strey DD Roberts GN Pavlakis Improved DNA: liposome complexes for increased systemic delivery and gene expression Nat Biotechnol 15 1997 647 652
2. F Liu H Qi L Huang D Liu Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration Gene Ther 4 1997 517 523
3. HE Hofland D Nagy JJ Liu K Spratt YL Lee O Danos In vivo gene transfer by intravenous administration of stable cationic lipid/DNA complex Pharm Res 14 1997 742 749
4. C Nicolazzi N Mignet N de la Figuera M Cadet RT Ibad J Seguin Anionic polyethyleneglycol lipids added to cationic lipoplexes increase their plasmatic circulation time J Control Release 88 2003 429 443
5. K Anwer G Kao B Proctor A Rolland S Sullivan Optimization of cationic lipid/DNA complexes for systemic gene transfer to tumor lesions J Drug Target 8 2000 125 135
6. K Anwer C Meaney G Kao N Hussain R Shelvin RM Earls Cationic lipid-based delivery system for systemic cancer gene therapy Cancer Gene Ther 7 2000 1156 1164
7. Y Liu A Thor E Shtivelman Y Cao G Tu TD Heath Systemic gene delivery expands the repertoire of effective antiangiogenic agents J Biol Chem 274 1999 13338 13344
8. E Wagner C Culmsee S Boeckle Targeting of polyplexes: toward synthetic virus vector systems Adv Genet 53PA 2005 333 354
9. JH Yu DV Schaffer Advanced targeting strategies for murine retroviral and adeno-associated viral vectors Adv Biochem Eng Biotechnol 99 2005 147 167
10. M Hashida S Kawakami F Yamashita Lipid carrier systems for targeted drug and gene delivery Chem Pharm Bull (Tokyo) 53 2005 871 880
11. M Thomas AM Klibanov Non-viral gene therapy: polycation-mediated DNA delivery Appl Microbiol Biotechnol 62 2003 27 34
12. RI Zhdanov OV Podobed VV Vlassov Cationic lipid-DNA complexes-lipoplexes-for gene transfer and therapy Bioelectrochemistry 58 2002 53 64
13. WM Pardridge Receptor-mediated peptide transport through the blood-brain barrier Endocr Rev 7 1986 314 330
14. GY Wu JM Wilson F Shalaby M Grossman DA Shafritz CH Wu Receptor-mediated gene delivery in vivo . Partial correction of genetic analbuminemia in Nagase rats J Biol Chem 266 1991 14338 14342
15. JM Wilson M Grossman CH Wu NR Chowdhury GY Wu JR Chowdhury Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits J Biol Chem 267 1992 963 967
16. JD Hood M Bednarski R Frausto S Guccione RA Reisfeld R Xiang Tumor regression by targeted gene delivery to the neovasculature Science 296 2002 2404 2407
17. E Ruoslahti D Rajotte An address system in the vasculature of normal tissues and tumors Annu Rev Immunol 18 2000 813 827
18. K Anwer G Kao A Rolland WH Driessen SM Sullivan Peptide-mediated gene transfer of cationic lipid/plasmid DNA complexes to endothelial cells J Drug Target 12 2004 215 221
19. K Temming RM Schiffelers G Molema RJ Kok RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature Drug Resist Updat 8 2005 381 402
20. T Nagasawa S Hirota K Tachibana N Takakura S Nishikawa Y Kitamura Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1 Nature 382 1996 635 638
21. R Salcedo JJ Oppenheim Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses Microcirculation 10 2003 359 370
22. F André JC Soria H Assi S Delaloge M Spielmann Expression of chemokine receptors by cancer cells Bull Cancer 91 Suppl 4 2004 S254 S256
23. H Tamamura K Hiramatsu M Mizumoto S Ueda S Kusano S Terakubo Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonists Org Biomol Chem 1 2003 3663 3669
24. H Tamamura K Hiramatsu S Kusano S Terakubo N Yamamoto JO Trent Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives Org Biomol Chem 1 2003 3656 3662
25. H Tamamura A Hori N Kanzaki K Hiramatsu M Mizumoto H Nakashima T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer FEBS Lett 550 2003 79 83
26. M Kucia R Reca K Miekus J Wanzeck W Wojakowski A Janowska-Wieczorek Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis Stem Cells 23 2005 879 894
27. EA Jaffe LW Hoyer RL Nachman Synthesis of von Willebrand factor by cultured human endothelial cells Proc Natl Acad Sci USA 71 1974 1906 1909
28. SA Rosenberg P Aebersold K Cornetta A Kasid RA Morgan R Moen Gene transfer into humans—immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction N Engl J Med 323 1990 570 578
29. V Krasnykh I Dmitriev G Mikheeva CR Miller N Belousova DT Curiel Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob J Virol 72 1998 1844 1852
30. TJ Wickham E Tzeng LL 2nd Shears PW Roelvink Y Li GM Lee Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins J Virol 71 1997 8221 8229
31. H Büning MU Ried L Perabo FM Gerner NA Huttner J Enssle Receptor targeting of adeno-associated virus vectors Gene Ther 10 2003 1142 1151
32. MU Ried A Girod K Leike H Büning M Hallek Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors J Virol 76 2002 4559 4566
33. JW Park K Hong DB Kirpotin G Colbern R Shalaby J Baselga Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery Clin Cancer Res 8 2002 1172 1181
34. M Toi S Kondo H Suzuki Y Yamamoto K Inada T Imazawa Quantitative analysis of vascular endothelial growth factor in primary breast cancer Cancer 77 1996 1101 1106
35. A Sehgal C Keener AL Boynton J Warrick GP Murphy CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells J Surg Oncol 69 1998 99 104
36. A Müller B Homey H Soto N Ge D Catron ME Buchanan Involvement of chemokine receptors in breast cancer metastasis Nature 410 2001 50 56
37. A Salmaggi M Eoli S Frigerio A Silvani M Gelati E Corsini Intracavitary VEGF, bFGF, IL-8, IL–12 levels in primary and recurrent malignant glioma J Neurooncol 62 2003 297 303
38. M Bermejo J Martín-Serrano E Oberlin MA Pedraza A Serrano B Santiago Activation of blood T lymphocytes down-regulates CXCR4 expression and interferes with propagation of X4 HIV strains Eur J Immunol 28 1998 3192 3204
39. RO Dillman Monoclonal antibodies in the treatment of malignancy: basic concepts and recent developments Cancer Invest 19 2001 833 841
40. Y Cheng WH Prusoff Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction Biochem Pharmacol 22 1973 3099 3108
41. J Di Salvo GE Koch KE Johnson AD Blake BL Daugherty JA DeMartino The CXCR4 agonist ligand stromal derived factor-1 maintains high affinity for receptors in both G α (i)-coupled and uncoupled states Eur J Pharmacol 409 2000 143 154
42. J Folch I Ascoli M Lees JA Meath N LeBaron Preparation of lipide extracts from brain tissue J Biol Chem 191 1951 833 841
43. S Li FC MacLaughlin JG Fewell Y Li V Mehta MF French Increased level and duration of expression in muscle by co-expression of a transactivator using plasmid systems Gene Ther 6 1999 2005 2011