Activation of the epidermal growth factor receptor by hydrogels in artificial tears

Experimental Eye Research

Volumn 86, Issue 3, 2008, Pages 500-505

  Lozano, Jennifer S ^a   Chay, Edward Y ^a   Healey, Jeffrey ^a   Sullenberger, Rebecca ^a   Klarlund, Jes K ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

carboxymethyl cellulose; corneal wound healing; hydrogel; hydroxypropylmethyl cellulose; methyl cellulose; polyvinyl alcohol; povidone

Indexed keywords

ARTIFICIAL TEAR; CARBOXYMETHYLCELLULOSE; EMOLLIENT AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; POLYMER; POLYVINYL ALCOHOL; POVIDONE;

ANIMAL TISSUE; ARTICLE; CELL MOTILITY; CORNEA EPITHELIUM; CORNEA INJURY; DRY EYE; HUMAN; HUMAN CELL; HYDROGEL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; VISCOSITY; WOUND HEALING;

ANIMALS; CELL LINE; CORNEA; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROGELS; LIMBUS CORNEAE; METHYLCELLULOSE; OPHTHALMIC SOLUTIONS; ORGAN CULTURE TECHNIQUES; RABBITS; RECEPTOR, EPIDERMAL GROWTH FACTOR; WOUND HEALING;

EID: 39849084347     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2007.12.003     Document Type: Article

References (45)

1. Aslan M., and Ozben T. Oxidants in receptor tyrosine kinase signal transduction pathways. Antioxid. Redox Signal. 5 (2003) 781-788
2. Baldwin H.C., and Marshall J. Growth factors in corneal wound healing following refractive surgery: a review. Acta Ophthalmol. Scand. 80 (2002) 238-247
3. Batzer A.G., Rotin D., Urena J.M., Skolnik E.Y., and Schlessinger J. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor. Mol. Cell. Biol. 14 (1994) 5192-5201
4. Bazley L.A., and Gullick W.J. The epidermal growth factor receptor family. Endocr. Relat. Cancer 12 Suppl. 1 (2005) S17-S27
5. Blagoev B., Ong S.E., Kratchmarova I., and Mann M. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat. Biotechnol. 22 (2004) 1139-1145
6. Block E.R., Matela A.R., SundarRaj N., Iszkula E.R., and Klarlund J.K. Wounding induces motility in sheets of corneal epithelial cells through loss of spatial constraints: role of heparin-binding epidermal growth factor-like growth factor signaling. J. Biol. Chem. 279 (2004) 24307-24312
7. Brown G.L., Curtsinger L.J., White M., Mitchell R.O., Pietsch J., Nordquist R., von Fraunhofer A., and Schultz G.S. Acceleration of tensile strength of incisions treated with EGF and TGF-beta. Ann. Surg. 208 (1988) 788-794
8. Fischer O.M., Hart S., Gschwind A., and Ullrich A. EGFR signal transactivation in cancer cells. Biochem. Soc. Trans. 31 (2003) 1203-1208
9. Fu X., Li X., Cheng B., Chen W., and Sheng Z. Engineered growth factors and cutaneous wound healing: success and possible questions in the past 10 years. Wound Repair Regen. 13 (2005) 122-130
10. Garrett Q., Simmons P.A., Xu S., Vehige J., Zhao Z., Ehrmann K., and Willcox M. Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing. Investig. Ophthalmol. Vis. Sci. 48 (2007) 1559-1567
11. Gaton D.D., Stiebel-Kalish H., Loya N., Weinberger D., Kashtan Y., and Solomon A. The effect of tear substitute and silicone oil on re-epithelisation of the cornea. Eye 12 Pt. 1 (1998) 141-144
12. Gilbard J.P. The scientific context and basis of the pharmacologic management of dry eyes. Ophthalmol. Clin. North Am. 18 (2005) 475-484 v
13. Gipson I.K., Spurr-Michaud S., Argueso P., Tisdale A., Ng T.F., and Russo C.L. Mucin gene expression in immortalized human corneal-limbal and conjunctival epithelial cell lines. Investig. Ophthalmol. Vis. Sci. 44 (2003) 2496-2506
14. Holly F.J., and Esquivel E.D. Colloid osmotic pressure of artificial tears. J. Ocul. Pharmacol. 1 (1985) 327-336
15. Hori K., Sotozono C., Hamuro J., Yamasaki K., Kimura Y., Ozeki M., Tabata Y., and Kinoshita S. Controlled-release of epidermal growth factor from cationized gelatin hydrogel enhances corneal epithelial wound healing. J. Control. Release 118 (2007) 169-176
16. Imanishi J., Kamiyama K., Iguchi I., Kita M., Sotozono C., and Kinoshita S. Growth factors: importance in wound healing and maintenance of transparency of the cornea. Prog. Retin. Eye Res. 19 (2000) 113-129
17. Johnson M.E., and Murphy P.J. Changes in the tear film and ocular surface from dry eye syndrome. Prog. Retin. Eye Res. 23 (2004) 449-474
18. Kholodenko B.N., Demin O.V., Moehren G., and Hoek J.B. Quantification of short term signaling by the epidermal growth factor receptor. J. Biol. Chem. 274 (1999) 30169-30181
19. Klenkler B., and Sheardown H. Growth factors in the anterior segment: role in tissue maintenance, wound healing and ocular pathology. Exp. Eye Res. 79 (2004) 677-688
20. Lee J.W., Park J.H., and Robinson J.R. Bioadhesive-based dosage forms: the next generation. J. Pharm. Sci. 89 (2000) 850-866
21. Lezama R., Diaz-Tellez A., Ramos-Mandujano G., Oropeza L., and Pasantes-Morales H. Epidermal growth factor receptor is a common element in the signaling pathways activated by cell volume changes in isosmotic, hyposmotic or hyperosmotic conditions. Neurochem. Res. 30 (2005) 1589-1597
22. Lin C.P., and Boehnke M. Influences of methylcellulose on corneal epithelial wound healing. J. Ocul. Pharmacol. Ther. 15 (1999) 59-63
23. Lu L., Reinach P.S., and Kao W.W. Corneal epithelial wound healing. Exp. Biol. Med. (Maywood) 226 (2001) 653-664
24. Nakamura Y., Sotozono C., and Kinoshita S. The epidermal growth factor receptor (EGFR): role in corneal wound healing and homeostasis. Exp. Eye Res. 72 (2001) 511-517
25. Noecker R. Effects of common ophthalmic preservatives on ocular health. Adv. Ther. 18 (2001) 205-215
26. Oda K., Matsuoka Y., Funahashi A., and Kitano H. A comprehensive pathway map of epidermal growth factor receptor signaling. Mol. Syst. Biol. 1 (2005) 1-17
27. Odintsova E., Sugiura T., and Berditchevski F. Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1. Curr. Biol. 10 (2000) 1009-1012
28. Odintsova E., Voortman J., Gilbert E., and Berditchevski F. Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR. J. Cell Sci. 116 (2003) 4557-4566
29. Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., and Mann M. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127 (2006) 635-648
30. Patarca R., Rosenzwei J.A., Zuniga A.A., and Fletcher M.A. Benzalkonium salts: effects on G protein-mediated processes and surface membranes. Crit. Rev. Oncog. 11 (2000) 255-305
31. Peppas N.A., and Sahlin J.J. Hydrogels as mucoadhesive and bioadhesive materials: a review. Biomaterials 17 (1996) 1553-1561
32. Riley M.V., and Wilson G. Topical hydrogen peroxide and the safety of ocular tissues. Clao J. 19 (1993) 186-190
33. Salamat-Miller N., Chittchang M., and Johnston T.P. The use of mucoadhesive polymers in buccal drug delivery. Adv. Drug Deliv. Rev. 57 (2005) 1666-1691
34. Schoeberl B., Eichler-Jonsson C., Gilles E.D., and Muller G. Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors. Nat. Biotechnol. 20 (2002) 370-375
35. Schultz G., Khaw P.T., Oxford K., MaCauley S., Van Setten G., and Chegini N. Growth factors and ocular wound healing. Eye 8 Pt. 2 (1994) 184-187
36. Sheardown H., Wedge C., Chou L., Apel R., Rootman D.S., and Cheng Y.L. Continuous epidermal growth factor delivery in corneal epithelial wound healing. Investig. Ophthalmol. Vis. Sci. 34 (1993) 3593-3600
37. Spix J.K., Chay E.Y., Block E.R., and Klarlund J.K. Hepatocyte growth factor induces epithelial cell motility through transactivation of the epidermal growth factor receptor. Exp. Cell. Res. 313 (2007) 3319-3325
38. Sudhakar Y., Kuotsu K., and Bandyopadhyay A.K. Buccal bioadhesive drug delivery - a promising option for orally less efficient drugs. J. Control. Release 114 (2006) 15-40
39. Sweeney T.E., and Beuchat C.A. Limitations of methods of osmometry: measuring the osmolality of biological fluids. Am. J. Physiol. 264 (1993) R469-R480
40. Teramura Y., Ichinose J., Takagi H., Nishida K., Yanagida T., and Sako Y. Single-molecule analysis of epidermal growth factor binding on the surface of living cells. EMBO J. 25 (2006) 4215-4222
41. Warren C.M., and Landgraf R. Signaling through ERBB receptors: multiple layers of diversity and control. Cell. Signal. 18 (2006) 923-933
42. Wells A. Tumor invasion: role of growth factor-induced cell motility. Adv. Cancer Res. 78 (2000) 31-101
43. Wilson S.E., Netto M., and Ambrosio Jr. R. Corneal cells: chatty in development, homeostasis, wound healing, and disease. Am. J. Ophthalmol. 136 (2003) 530-536
44. Xu K.P., Ding Y., Ling J., Dong Z., and Yu F.S. Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells. Investig. Ophthalmol. Vis. Sci. 45 (2004) 813-820
45. Zieske J.D., Takahashi H., Hutcheon A.E., and Dalbone A.C. Activation of epidermal growth factor receptor during corneal epithelial migration. Investig. Ophthalmol. Vis. Sci. 41 (2000) 1346-1355