Population pharmacokinetics of atorvastatin, simvastatin & pravastatin after oral administration in humans

Saudi Pharmaceutical Journal

Volumn 16, Issue 1, 2008, Pages 82-84

  Idkaidek, Nasir M ^a   Najib, Naji M ^b   Arafat, Tawfiq ^c   Al Ghazawi, Ahmad ^d  

^a UNIVERSITY OF PETRA   (Jordan)

^b International Pharmaceutical Research Center   (Jordan)

^c Jordan Center for Pharmaceutical Research Amman   (Jordan)

^d Triumpharma LLC   (Jordan)

Author keywords

Kinetica; Pharmacokinetics; Population; Statins

Indexed keywords

ATORVASTATIN; PRAVASTATIN; SIMVASTATIN;

ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PHARMACOKINETICS; STATISTICAL ANALYSIS;

EID: 39749196921     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Naji Najib, Nasir Idkaidek, Adel A, Admour I, Astigarraga RE, Nucci GD, Alam SM, Dham R. Qumaruzaman. Pharmacokinetics& bioequivalence evaluation of two brands of simvastatin 40 mg tablets in healthy human volunteers. Biopharmaceutics & Drug Disposition. 2003; 24:183-89.
2. Nasir Idkaidek, Amidon GL, Smith DE, Najib NM, Hassan MM. Determination of Population Pharmacokinetic Parameters of Sustained Release and enteric Coated Oral Formulations, and the Suppository Formulation of Diclofenac Sodium by Simultaneous Data Fitting Using NONMEM. Biopharmaceutics and Drug Disposition; 1998; 19: 169-174.
3. Nasir Idkaidek and Naji Najib. Poplulation pharmacokinetics of azithromycin after peroral administration to healthy volunteers. Acta Pharmaceutica Turcica; 2001; XLIII (3,4): 151-154.
4. Kinetica Version 4.1, 2006, Inna Phase Inc., France.
5. th Edition, 2005, Mosby Inc., Missouri, USA
6. Stefano Bellosta, Rodolfo Paoletti, Alberto Corsini. Safety of Statins: Focus on Clinical Pharmacokinetics and Drug Interactions. Circulation. 2004;109[suppl III]:III-50-57.