Nitric oxide synthase inhibition promotes endothelium-dependent vasodilatation and the antihypertensive effect of L-serine

Hypertension

Volumn 51, Issue 3, 2008, Pages 791-796

  Mishra, Ramesh C ^a   Tripathy, Saswati ^a   Desai, Kaushik M ^a   Quest, Dale ^b   Lu, Yanjie ^a   Akhtar, Jawed ^a   Gopalakrishnan, Venkat ^a,c  

^a ROYAL UNIVERSITY HOSPITAL   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Amino acids; Blood pressure; Endothelium; Hypertension; Vasodilation

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; APAMIN; BARIUM ION; CALCIUM CHANNEL BLOCKING AGENT; CHARYBDOTOXIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; OUABAIN; PHENYLEPHRINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHLORIDE; SERINE; TRAM 34; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTERIOLE; ARTICLE; CARDIOVASCULAR EFFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; ENZYME INHIBITION; HEART RATE; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ARTERIOLES; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HEART RATE; MALE; MESENTERY; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RATS, SPRAGUE-DAWLEY; SERINE; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 39749175013     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.099598     Document Type: Article

References (25)