Neuropathology of Viral Infections of the Central Nervous System

Neuroimaging Clinics of North America

Volumn 18, Issue 1, 2008, Pages 19-39

  Shankar, Susarla K ^a   Mahadevan, Anita ^a   Kovoor, Jerry M E ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ARBOVIRUS; CENTRAL NERVOUS SYSTEM INFECTION; CYTOMEGALOVIRUS; EPSTEIN BARR VIRUS; FOLLOW UP; HENDRA VIRUS; HERPES SIMPLEX ENCEPHALITIS; HERPES ZOSTER; HUMAN; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS INFECTION; MEASLES; NEUROIMAGING; NEUROPATHOLOGY; NIPAH VIRUS; PANENCEPHALITIS; POLIOMYELITIS; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; RABIES; RETROVIRUS INFECTION; REVIEW; RUBELLA; SUBACUTE SCLEROSING PANENCEPHALITIS; VIRUS INFECTION;

ENCEPHALITIS, VIRAL; HUMANS; MAGNETIC RESONANCE IMAGING; NEURORADIOGRAPHY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 39749170478     PISSN: 10525149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nic.2007.12.009     Document Type: Review

References (116)

1. Hall C.B. Human herpes viruses at sixes, sevens and more. Ann Intern Med 127 (1997) 481-483
2. Goodpasture E.W., and Teague O. Transmission of virus of herpes fibrilis along nerve in experimentally infected rabbits. J Med Res 44 (1923) 139-184
3. Baringer J.R., and Pisani P. Herpes simplex virus genomes in human nervous system tissue analysed by polymerase chain reaction. Ann Neurol 36 (1994) 823-829
4. Twomey J.A., Barker C.M., Robinson G., et al. Olfactory mucosa in herpes simplex encephalitis. J Neurol Neurosurg Psychiatry 42 (1979) 983-987
5. Whitley R., Lakeman A.D., Nahmias A.J., et al. DNA restriction enzyme analysis of herpes simplex virus isolated from the patients with encephalitis. N Engl J Med 307 (1982) 1060-1062
6. Lakeman F.D., and Whitley R.J. Diagnosis of herpes simplex encephalitis: application of polymerase chain reaction cerebrospinal fluid from brain-biopsied patients and correlation with disease. J Infect Dis 171 (1995) 857-863
7. Anrelius E., Johansson B., Skddenberg B., et al. Rapid diagnosis of herpes simplex encephalitis by nested polymerase chain reaction assay of cerebrospinal fluid. Lancet 337 (1991) 189-192
8. Esiri M.M. Herpes simplex encephalitis. An immunohistological study of the distribution of viral antigen within the brain. J Neurol Sci 54 (1982) 209-226
9. Kennedy P.G., Adams J.H., Graham D.I., et al. Clinicopathological study of herpes simplex encephalitis. Neuropathol Appl Neurobiol 14 (1988) 395-415
10. Nicoll J.A., Maitland N.J., and Love S. Use of polymerase chain rection to detect herpes simplex virus DNA in paraffin sections of human brain at necropsy. J Neurol Neurosurg Psychiatry 54 (1991) 167-168
11. Nakajima H., Furutama D., Kimura F., et al. Herpes simplex virus myelities: clinical manifestation and diagnosis by the polymerase chain reaction method. Eur Neurol 39 (1998) 163-167
12. Iwamasa T., Yoshitake H., Sakuda H., et al. Acute ascending necrotising myelitis in Okinava caused by herpes simplex virus type-2. Virchows Arch A Pathol Anat Histopathol 418 (1991) 71-75
13. Whitley R.J. Neonatal Herpes simplex virus infection: pathogenesis and therapy. Pathol Biol (Paris) 40 (1992) 729-734
14. Chang Y., Soffer D., Horoupian D.S., et al. Evolution of post-natal herpes simplex virus encephalitis to multicystic encephalopathy. Acta Neuropathol 80 (1990) 666-670
15. Caserta H.T., Hall C.B., Schnabel K., et al. Primary human herpes virus 7 infection: a comparison of human herpes virus 7 and human herpes virus 6 infections in children. J pediatr 133 (1998) 386-389
16. Yamanishi K. Pathogenesis of human herpes virus 6 (HHV-6). Infect Agents Dis 1 (1992) 149-155
17. Lusso P., Secchiero P., Crowly R.W., et al. CD4 is a critical component of receptor for human herpes virus 7 interference with human immunodeficiency virus. Proc Natl Acad Sci U S A 91 (1994) 3872-3876
18. Luppi M., Barozzi P., Morris C., et al. Human herpes virus 6 latently infects early bone marrow progenitors in vivo. J virol 73 (1999) 754-759
19. Liedtke W., Trubner K., and Schwechheimer K. On the role of human herpes virus 6 in viral latency in nervous tissue and in cerebral lymphoma. J Neurol Sci 134 (1995) 184-188
20. Kondo K., Kondo T., Okuno T., et al. Latent human herpes virus 6 infection of human monocytes/macrophages. J Gen Virol 72 (1991) 1401-1408
21. Kondo K., Nagafuji H., Hata A., et al. Association of human herpes virus 6 infection of the central nervous system with recurrence of febrile convulsions. J Infect Dis 167 (1993) 1197-1200
22. Suga S., Yoshikawa T., Nagai T., et al. Clinical features and virological findings in children with primary human herpes virus 7 infection. Pediatrics (1997) 99-104
23. Ambroziak J.A., Blackbourn D.J., Herndier B.G., et al. Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients. Science 268 (1995) 582-583
24. Dupin N., Gorin I., Deleuze J., et al. Herpes-like DNA sequences, AIDS-related tumors, and Castleman's disease. [letter]. N Engl J Med 333 (1995) 798-799
25. Davison A.J., and McGeoch D.J. Evolutionary comparisons of the S segments in the genomes of herpes simplex virus type 1 and varicella-zoster virus. J Gen Virol 67 (1986) 597-611
26. Gilden D.H., La Guardia J.J., Mahalimgam R., et al. Neurological complications of Varicella - zoster virus. In: Davis L.E., and Kennedy P.G.E. (Eds). Infectious diseases of nervous system (2000), Butterworth-Heinemann, Oxford (UK) 291-320
27. Gershon A.A., Mervish N., LaRussa P., et al. Varicella-zoster virus infection in children with underlying human immunodeficiency virus infection. J Infect Dis 176 (1997) 1496-1500
28. Cinque P., Bossolasco S., Vago L., et al. Varicella-zoster virus (VZV) DNA in cerebrospinal fluid of patients infected with human immunodeficiency virus: VZV disease of the central nervous system or subclinical reactivation of VZV infection?. Clin Infect Dis 25 (1997) 634-639
29. Kennedy P.G.E., Grinfeld E., and Gow J.W. Latent Varicella-zoster virus in human dorsal root ganglia. Virology 258 (1999) 451-454
30. Hyman R.W., Ecker J.R., and Tenser R.B. Varicella-zoster virus RNA in human trigeminal ganglia. Lancet 2 (1983) 814-816
31. Abendroth A., and Arvin A. Varicella-zoster virus immune evasion. Varicella-zoster virus immune evasion. Immunol Rev 168 (1999) 143-156
32. Tselis A., and Lavi E. Cytomegalo virus infection of the nervous system. In: Davis L.E., and Kennedy P.G.E. (Eds). Infectious diseases of the nervous system (2000), Butterworth-Heineman, Oxford (UK) 109-138
33. Pillay D., Lipman M.C., Lee C.A., et al. A clinico-pathological audit of opportunistic viral infections in HIV-infected patients. AIDS 7 (1993) 969-974
34. Shepp D.H., Moses J.E., and Kaplan M.H. Sero epidemiology of cytomegalovirus in patients with advanced HIV disease: influence on expression and survival. J Acquir Immune Defic Syndr Hum Retrovirol 11 (1996) 460-468
35. Holland N.R., Power C., Mathews V.P., et al. Cytomegalovirus encephalitis in acquired immunodeficiency syndrome. Neurology 44 (1994) 507-514
36. Cornford M.E., Ho H.W., and Vinters H.V. Correlation of neuromuscular pathology in acquired immune deficiency syndrome patients with cytomegalovirus infection and zidovudine treatment. Acta Neuropathol 84 (1992) 516-529
37. Schopfer K., Lauber E., and Krech U. Congenital cytomegalovirus virus infection in new born infants of mothers infected before pregnancy. Arch Dis Child 53 (1978) 536-539
38. Pass R.F., Stagno S., Myers G.J., et al. Outcome of symptomatic congenital cytomegalovirus infection: results of long-term longitudinal follow-up. Pediatrics 66 (1980) 758-762
39. Ballard R.A., Drew W.L., Hufnagle K.G., et al. Acquired cytomegalovirus infection in preterm infants. Am J Dis Child 133 (1979) 482-485
40. Friede R. Developmental neuropathology (1989), Springer, New York p. 158-160
41. Vago L., Nebuloni M., Sala E., et al. Coinfection of the central nervous system by cytomegalovirus and herpes simplex virus type 1 or 2 in AIDS patients: autopsy study on 82 cases by immunohistochemistry and polymerase chain reaction. Acta Neuropathol 92 (1996) 404-408
42. Roullet E. Opportunistic infections of the central nervous system during HIV-1 infection (emphasis on cytomegalovirus disease). J Neurol 246 (1999) 237-243
43. Epstein M.A., Achong B.G., and Barr Y.M. Virus particles in cultured lymphoblasts from Burkitts Lymphoma. Lancet 1 (1964) 702-703
44. Griffin B.E., and Xue S.A. Epstein-Barr virus infections and their association with human malignancies: some key questions. Ann Med 30 (1998) 249-259
45. Bray P.F., Luka J., Bray P.F., et al. Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein. Neurology 42 (1992) 1798-1804
46. Hilton D.A., Love S., Fletcher A., et al. Absence of Epstein-Barr virus RNA in multiple sclerosis as assessed by insitu hybridisation. J Neurol Neurosurg Psychiatry 57 (1994) 975-976
47. Wong K.T. Emerging and re-emerging epidemic encephalitis: a tale of two viruses. Neuropathol Appl Neurobiol 26 (2000) 313-318
48. Chua K.B., Goh K.J., and Wong K.T. Fatal encephalitis due to Nipah virus among pig-farmers in Malaysia. Lancet 354 (1999) 1257-1259
49. O'Sullivan J.D., Allworth A.M., Paterson D.L., et al. Fatal encephalitis due to novel paramyxovirus transmitted from horses. Lancet 349 (1997) 93-95
50. Paton N.I., Leo Y.S., Zaki S.R., et al. Outbreak of Nipah-virus infection among abattoir workers in Singapore. Lancet 354 (1999) 1253-1256
51. Green R.H., Balsamo M.R., Giles J.P., et al. Studies of the natural history and prevention of Rubella. Am J Dis Child 110 (1965) 348-365
52. Neggie A.D., and Robbins F.C. Natural rubella acquired after birth: clinical features and complications. Am J Dis Child 118 (1969) 12-17
53. Desmond M.M., Wilson G.S., and Melnick J.L. Congenital rubella encephalitis. Course and early sequelae. J Pediatr 71 (1967) 311-331
54. Rorke L.B., and Spiro A.J. Cerebral lesions in congenital rubella syndrome. J Pediatr 70 (1967) 243-255
55. Roos R.P., Graves M.C., Wollmann R.L., et al. Immunologic and virologic studies of measles inclusion body encephalitis in an immunosuppressed host: the relationship to subacute sclerosing panencephalitis. Neurology 31 (1981) 1263-1270
56. Baczko K., Liebert U.G., Cattaneo R., et al. Restriction of measles virus gene expression in measles inclusion body encephalitis. J Infect Dis 158 (1988) 144-150
57. Suryanarayana K., Baczko K., ter Meulen V., et al. Transcription inhibition and other properties of matrix proteins expressed by M genes cloned from measles viruses and diseased human brain tissue. J Virol 68 (1994) 1532-1543
58. Zilber N., Rannon L., Alter M., et al. Measles, measles vaccination, and risk of subacute sclerosing panencephalitis (SSPE). Neurology 33 (1983) 1558-1564
59. Modlin J.F., Halsey N.A., Eddins D.L., et al. Epidemiology of subacute sclerosing panencephalitis. J Pediatr 94 (1979) 231-236
60. Cattaneo R., Schmid A., Billeter M.A., et al. Multiple viral mutations rather than host factors cause defective measles virus gene expression in a subacute sclerosing panencephalitis cell line. J Virol 62 (1988) 1388-1397
61. Schmid A., Spielhofer P., Cattaneo R., et al. Subacute sclerosing panencephalitis is typically characterized by alterations in the fusion protein cytoplasmic domain of the persisting measles virus. Virology 188 (1992) 910-915
62. Modlin J.F., Jabbour J.T., Witte J.J., et al. Epidemiologic studies of measles, measles vaccine, and subacute sclerosing panencephalitis. Pediatrics 59 (1977) 505-512
63. Allen I.V., McQuaid S., McMahon J., et al. The significance of measles virus antigen and genome distribution in the CNS in SSPE for mechanisms of viral spread and demyelination. J Neuropathol Exp Neurol 55 (1996) 471-480
64. Mandybur T.I. The distribution of Alzheimer's neurofibrillary tangles and gliosis in chronic subacute sclerosing panencephalitis. Acta Neuropathol 80 (1990) 307-310
65. Holman R.C., Torok T.J., Belay E.D., et al. Progressive multifocal leukoencephalopathy in the United States, 1979-1994: increased mortality associated with HIV infection. Neuroepidemiology 17 (1998) 303-309
66. Shah K.V., Fields B.N., Knipe D.M., et al. Polyoma viruses. In: Fields B.N., Knipe D.M., and Howley P.N. (Eds). Field's text book of virology (1990), Raven Press, New York 1609-1623
67. Dorries K. Molecular biology and pathogenesis of human polyomavirus infections. Dev Biol Stand 94 (1998) 71-79
68. Rockwell D., Ruben F.L., Winkelstein A., et al. Absence of imune deficiencies in a case of progressive multifocal leukoencephalopathy. Am J Med 61 (1976) 433-436
69. Ernst T., Chang L., Witt M., et al. Progressive multifocal leukoencephalopathy and human immunodeficiency virus-associated white matter lesions in AIDS: magnetization transfer MR imaging. Radiology 210 (1999) 539-543
70. Garcia de Viedma D., Alonso R., Miralles P., et al. Dual qualitative-quantitative nested PCR for detection of JC virus in cerebrospinal fluid: high potential for evaluation and monitoring of progressive multifocal leukoencephalopathy in AIDS patients receiving highly active antiretroviral therapy. J Clin Microbiol 37 (1999) 724-728
71. Antinori A., Ammassari A., De Luca A., et al. Diagnosis of AIDS-related focal brain lesions: a decision-making analysis based on clinical and neuroradiologic characteristics combined with polymerase chain reaction assays in CSF. Neurology 48 (1997) 687-694
72. Clifford D.B., Yiannoutsos C., Glicksman M., et al. HAART improves prognosis in HIV-associated progressive multifocalleukoencephalopathy. Neurology 52 (1999) 623-625
73. Kuchelmeister K., Bergmann M., and Gullotta F. Cellular changes in the cerebellar granular layer in AIDS-associated PML. Neuropathol Appl Neurobiol 19 (1993) 398-401
74. Rosen L., Tesh R.B., Lien J.C., et al. Transovarian transmission of Japanese encephalitis virus by mosquitoes. Science 199 (1978) 909-911
75. Ogata A., Nagashima K., Hall W.W., et al. Japanese encephalitis virus neurotropism is dependent on the degree of neuronal maturity. J Virol 65 (1991) 880-886
76. Desai A., Shankar S.K., Ravi V., et al. Japanese encephalitis virus antigen in the human brain and its topographic distribution. Acta Neuropathol 89 (1995) 368-373
77. Kimoto T., Yamada T., Uebe N., et al. Laboratory diagnosis of Japanese encephalitis: comparison of the fluorescent antibody technique with virus isolation and serological tests. Biken J 11 (1968) 157-168
78. Ravi V., Desai A.S., Shenoy P.K., et al. Persistence of Japanese encephalitis virus in the human nervous system. J Med Virol 40 (1993) 326-329
79. WHO report of a Working group on Japanese encephalitis in centre for Disease control. MMWR Morb Mortal wkly Rep 33 (1992) 119-125
80. Weaver S.C., Salas R., Rico-Hesse R., et al. Re-emergence of epidemic Venezuelan equine encephalomyelitis in South America. VEE Study Group. Lancet 348 (1996) 436-440
81. Chaturvedi U.C., Mathur A., Chandra A., et al. Transplacental infection with Japanese encephalitis virus. J Infect Dis 141 (1980) 712-715
82. Misra U.K., Kalita J., Jain S.K., et al. Radiological and neurophysiological changes in Japanese encephalitis. J Neurol Neurosurg Psychiatry 57 (1994) 1484-1487
83. Solomon T., Kneen R., Dung N.M., et al. Poliomyelitis-like illness due to Japanese encephalitis virus. Lancet 351 (1998) 1094-1097
84. Misra U.K., and Kalita J. Anterior horn cells are also involved in Japanese encephalitis. Acta Neurol Scand 96 (1997) 114-117
85. Esiri M.M. Viruses and rickettsiae. Brain Pathol 7 (1997) 695-709
86. Johnson R.T., Burke D.S., Elwell M., et al. Japanese encephalitis: immunocytochemical studies of viral antigen and inflammatory cells in fatal cases. Ann Neurol 18 (1985) 567-573
87. Desai A., Ravi V., Chandramuki A., et al. Detection of immune complexes in the CSF of Japanese encephalitis patients: correlation of findings with outcome. InterVirology 37 (1995) 352-355
88. Shankar S.K., Rao T.V., Mruthyunjayanna B.P., et al. Autopsy study of brains during an epidemic of Japanese encephalitis in Karnataka. Indian J Med Res 78 (1983) 431-440
89. Ishii T., Matsushita M., and Hamada S. Characteristic residual neuropathological features of Japanese B encephalitis. Acta Neuropathol 38 (1977) 181-186
90. Desai A., Shankar S.K., Jayakumar P.N., et al. Co-existence of cerebral cysticercosis with Japanese encephalitis: a prognostic modulator. Epidemiol Infect 118 (1997) 165-171
91. World Health Organization. Position paper on Japanese Encephalitis. Wkly Epidemiol Rec 44 (1998) 337-344
92. Mendelsohn C.L., Wimmer E., and Racaniello V.R. Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell 56 (1989) 855-865
93. Isaacson S.H., Sivakumar K., Asher D.M., et al. Cellular localization of poliovirus RNA in the spinal cord during acute paralytic poliomyelitis. Ann N Y Acad Sci 753 (1995) 194-200
94. Kaminski H.J., Tresser N., Hogan R.E., et al. Spinal cord histopathology in long-term survivors of poliomyelitis. Muscle Nerve 18 (1995) 1208-1209
95. Leon-Monzon M.E., and Dalakas M.C. Detection of poliovirus antibodies and poliovirus genome in patients with the post-polio syndrome. Ann N Y Acad Sci 753 (1995) 208-218
96. Human rabies prevention-United States, 1999. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 48 RR-1 (1999) 1-21
97. Charlton K.M., Nadin-Davis S., Casey G.A., et al. The long incubation period in rabies: delayed progression of infection in muscle at the site of exposure. Acta Neuropathol 94 (1997) 73-77
98. Koprowski H., Zheng Y.M., Heber-Katz E., et al. In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases. Proc Natl Acad Sci U S A 90 (1993) 3024-3027
99. Koschel K., and Munzel P. Inhibition of opiate receptor-mediated signal transmission by rabies virus in persistently infected NG-108-115 mouse neuroblastoma-rat glioma hybrid cells. Proc Natl Acad Sci U S A 81 (1984) 950-954
100. Nagaraj T., Vasanth J.P., and Desai A. Antemortem diagnosis of human rabies using saliva samples: comparison of real time and conventional RT-PCR techniques. J Clin Virol 36 (2006) 17-23
101. Bingham J., and Mlambo P. Ante-mortem diagnosis of human rabies by the skin biopsy technique: three case reports from Zimbabwe. Cent Afr J Med 41 (1995) 258-260
102. Global summary of the AIDS epidemic-December 2006. Available at: www.unacids.org.
103. Quinn T.C. Global burden of the HIV pandemic. Lancet 348 (1996) 99-106
104. Lucas S.B., Hounnou A., Peacock C., et al. The mortality and pathology of HIV infection in a west African city. AIDS 7 (1993) 1569-1579
105. Maehlen J., Dunlop O., Liestol K., et al. Changing incidence of HIV-induced brain lesions in Oslo, 1983-1994: effects of zidovudine treatment. AIDS 9 (1995) 1165-1169
106. Martinez A.J., Sell M., Mitrovics T., et al. The neuropathology and epidemiology of AIDS. A Berlin experience. A review of 200 cases. Pathol Res Pract 191 (1995) 427-443
107. Oleske J.M., et al. Diagnostic criteria of pediatric AIDS. In: Kozlowski P.B., Snider D.A., Vietze D.M., et al. (Eds). Brain pediatric AIDS (1990), Karger, Basel (Switzerland) 13-17
108. Shearer L.P., and Mintz M. Neuropathology of AIDS in children. In: Scaravilli F. (Ed). The neuropathology of HIV infection (1993), Springer Verlag, London 201-214
109. Dal Pan G.J., McArthur J.H., and Aylward E. Patterns of cerebral atrophy in HIV-1-infected individuals: results of a quantitative MRI analysis. Neurology 42 (1992) 2125-2130
110. Janssen R.S., Nwanyanwu O.C., Selik R.M., et al. Epidemiology of human immunodeficiency virus encephalopathy in the United States. Neurology 42 (1992) 1472-1476
111. Rottenberg D.A., Moeller J.R., Strother S.C., et al. The metabolic pathology of the AIDS dementia complex. Ann Neurol 22 (1987) 700-706
112. Budka H. Multinucleated giant cells in brain: a hallmark of the acquired immune deficiency syndrome (AIDS). Acta Neuropathol 69 (1986) 253-258
113. Belman A. Neurologic syndromes associated with symptomatic human immunodeficiency virus infection in infants and children. In: Kozlowski P.B., Snider D.A., Vietez P.M., et al. (Eds). Brain in pediatric AIDS (1990), Krager, Basel (Switzerland) 45-63
114. Hara H., Morita M., Iwaki T., et al. Detection of human T lymphotrophic virus type I (HTLV-I) proviral DNA and analysis of T cell receptor V beta CDR3 sequences in spinal cord lesions of HTLV-I-associated myelopathy/tropical spastic paraparesis. J Exp Med 180 (1994) 831-839
115. Lenky T.J., Fox C.H., Koenig S., et al. Detection of human T lymphotrophic virus type 1 (HTLV-1) tax RNA in the Central Nervous system of HTLV-1 associated myelopathy tropical spastic paraparesis by insitu hybridisdation. Ann Neurol 37 (1995) 246-254
116. Kubota R., Fujiyoshi T., Izumo S., et al. Fluctuation of HTLV -1 proviral DNA in peripheral blood mononuclear cells of HTLV-1 associated myelopathy. J Neuroimmunol 43 (1993) 147-154