Lipophilicity of 5′-carbonates of lamivudine with antiretroviral activity. Correlation between different methods

Journal of Liquid Chromatography and Related Technologies

Volumn 31, Issue 7, 2008, Pages 1014-1032

  Ravetti, Soledad ^a   Gualdesi, María Soledad ^a   Briñón, Margarita Cristina ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

5 Carbonates of lamivudine; CLOGP; Lipophilicity; Log P oct; RP HPLC; RP TLC

Indexed keywords

ANTI-HIV ACTIVITY; ANTIRETROVIRAL ACTIVITY; LIPOPHILICITY;

CARBONATES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; THIN LAYER CHROMATOGRAPHY;

BIOTECHNOLOGY;

2',3' DIDEOXYTIACYTIDINE 2 PRO (2',3' DIDEOXY 3' THIACYTIDIN 5' YL O 2 PROPYL CARBONATE; 2',3' DIDEOXYTIACYTIDINE BUTA (2',3' DIDEOXY 3' THIACYTIDIN 5' YL O BUTYL CARBONATE; 2',3' DIDEOXYTIACYTIDINE ETHA (2',3' DIDEOXY 3' THIACYTIDIN 5' YL O ETHYL CARBONATE; 2',3' DIDEOXYTIACYTIDINE HEXA (2',3' DIDEOXY 3' THIACYTIDIN 5' YL O HEXYL CARBONATE; 2',3' DIDEOXYTIACYTIDINE METHA (2',3' DIDEOXY 3' THIACYTIDIN 5' YL O METHYL CARBONATE; 2',3' DIDEOXYTIACYTIDINE OCTA (2',3' DIDEOXY 3' THIACYTIDIN 5' YL O OCTYL CARBONATE; 2',3' DIDEOXYTIACYTIDINE PENTA (2',3' DIDEOXY 3' THIACYTIDIN 5' YL O PENTYL CARBONATE; 2',3' DIDEOXYTIACYTIDINE PRO (2',3' DIDEOXY 3' THIACYTIDIN 5' YL O PROPYL CARBONATE; CARBONIC ACID DERIVATIVE; LAMIVUDINE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CORRELATION ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOPHILICITY; PARTITION COEFFICIENT; THIN LAYER CHROMATOGRAPHY; VALIDITY;

EID: 39749166233     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070801924857     Document Type: Article

References (26)