Intramolecular acid-base catalysis of a phosphate diester: Modeling the ribonuclease mechanism

Journal of the American Chemical Society

Volumn 130, Issue 8, 2008, Pages 2436-2437

  Orth, Elisa S ^a   Brandão, Tiago A S ^a   Milagre, Humberto M S ^b   Eberlin, Marcos N ^b   Nome, Faruk ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANOPHOSPHATE; RIBONUCLEASE;

ACID BASE BALANCE; ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; DISSOCIATION; ENZYME ACTIVITY; ENZYME MECHANISM; HYDROLYSIS KINETICS; HYDROPHOBICITY; MASS SPECTROMETRY; PH; PHASE TRANSITION; REACTION ANALYSIS; TEMPERATURE DEPENDENCE;

ACIDS; BINDING SITES; CATALYSIS; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; IMIDAZOLES; KINETICS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOSPHATES; PHOSPHORIC ACID ESTERS; RIBONUCLEASE, PANCREATIC; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

EID: 39749152753     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja710693x     Document Type: Article

References (16)